General information for g8135.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 2-acylglycerol O-acyltransferase 1.
Parent gene
- The parent gene g8135 is located on chr_2: 28746187..28747699 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8135 | g8135.t3 | TSS | g8135.t3 | 28744788 | 28744788 |
| chr_2 | g8135 | g8135.t3 | isoform | g8135.t3 | 28744922 | 28746187 |
| chr_2 | g8135 | g8135.t3 | exon | g8135.t3.exon1 | 28744922 | 28745119 |
| chr_2 | g8135 | g8135.t3 | exon | g8135.t3.exon2 | 28745196 | 28745283 |
| chr_2 | g8135 | g8135.t3 | cds | g8135.t3.CDS1 | 28745237 | 28745283 |
| chr_2 | g8135 | g8135.t3 | exon | g8135.t3.exon3 | 28745353 | 28746187 |
| chr_2 | g8135 | g8135.t3 | cds | g8135.t3.CDS2 | 28745353 | 28746187 |
| chr_2 | g8135 | g8135.t3 | TTS | g8135.t3 | 28746322 | 28746322 |
Sequences
>g8135.t3 Gene=g8135 Length=1121
ATGAATGAAGATAAAATAAGTTTTCTGAGAAAACATGTTGTTATTATCAATTATGTCCGA
TCATTTTTAAAATCAATTAAATTTGCACCAATTAATGTGCCTTTTAATCAAAGATGTGAA
GTTTTTAGCGCTTTTCTATTTATTTCAATGGTCTTGTTTGCTGAAGCATTATGTGTTCTA
ATCATTTATTTTTTACTCGTTTAGTGGGCCAAATATTTTGTATCGGGTATTTTGCATTTA
TGATAAGTGATATAAAAGCAGATGAAACTGGAATAAGAGGTCAAGGATCAAAATGGGTGC
GCTCTTGGAAATGGTGGAAATATTATGCAAACTATTTTCCTGTTAAACTCATCAAAACTG
TTGATCTTCCACCAAATAAAAATTATTTATTTGGATGTTTTCCGCATGCTATCATCGGAT
GCGGTCTTTTTGCAAATTTTGCAACAAATGCGACAGGATTTAATGAAAATTTTCCTGGAA
TAAGGTCAAAAATGTGTACACTTTCATTTCATTTTTATGTGCCATTTTTTAGAGAGCTTG
CTTTCTCGTGGGGTCTAATGTCAGCAAAGTATGTTTCTATAAAACAAGCTCTCTCTCAAT
CAACAAATCCTTTAGCAGTAGCAAATCAAGCTGATAAATTTACGAGTAATGCTGTAGTTT
TGGTAGTTGGTGGAGCTCAAGAAGCACTAATGTCTCATCCTGGGAAATATGAAATTTTTA
TAAAAAGTCGCAAAGGATTTATCAAAATTGCGCTTGAAACTGGAGCATCTCTTGTACCGG
TCTTCTCTTTTGGAGAAACCGAGGTTTATGATCAAACACCAAATGAACCAGGGAGCAAAG
TTAGAAGGTTTCAGGAAGCATTTAAAAAATGGACGGGTGTCGCTCCCGCAATTTTTATTG
GTCGAGGATTTTTTCAATATTCTTTTGGTCTCATTCCACGACGTGCTCCGATTCATACCA
TTGTTGGTGCACCTATTGCTGTCGAAAAGATTTTATCACCTTCAAAAGAGGATATTGATA
ATTTGCATCAAAAATTCATTGAAGAACTTGAGAAATTATTTGAAGAGCATAAAAGAAAAT
ATATTCCAAATGCTGAAAATGTTAAATTGATTATGAGATAA
>g8135.t3 Gene=g8135 Length=293
MISDIKADETGIRGQGSKWVRSWKWWKYYANYFPVKLIKTVDLPPNKNYLFGCFPHAIIG
CGLFANFATNATGFNENFPGIRSKMCTLSFHFYVPFFRELAFSWGLMSAKYVSIKQALSQ
STNPLAVANQADKFTSNAVVLVVGGAQEALMSHPGKYEIFIKSRKGFIKIALETGASLVP
VFSFGETEVYDQTPNEPGSKVRRFQEAFKKWTGVAPAIFIGRGFFQYSFGLIPRRAPIHT
IVGAPIAVEKILSPSKEDIDNLHQKFIEELEKLFEEHKRKYIPNAENVKLIMR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g8135.t3 | CDD | cd07987 | LPLAT_MGAT-like | 29 | 279 | 2.47791E-54 |
| 4 | g8135.t3 | Coils | Coil | Coil | 256 | 276 | - |
| 2 | g8135.t3 | PANTHER | PTHR12317 | DIACYLGLYCEROL O-ACYLTRANSFERASE | 7 | 289 | 2.4E-102 |
| 3 | g8135.t3 | PANTHER | PTHR12317:SF0 | DIACYLGLYCEROL O-ACYLTRANSFERASE 1 | 7 | 289 | 2.4E-102 |
| 1 | g8135.t3 | Pfam | PF03982 | Diacylglycerol acyltransferase | 14 | 283 | 9.2E-100 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | MF |
KEGG
Orthology
- This transcript has been annotated with K14457 (2-acylglycerol O-acyltransferase 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
