General information for g8145.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Adenine phosphoribosyltransferase.
Parent gene
- The parent gene g8145 is located on chr_2: 28783540..28784242 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8145 | g8145.t1 | TSS | g8145.t1 | 28783191 | 28783191 |
| chr_2 | g8145 | g8145.t1 | isoform | g8145.t1 | 28783379 | 28784063 |
| chr_2 | g8145 | g8145.t1 | exon | g8145.t1.exon1 | 28783379 | 28783473 |
| chr_2 | g8145 | g8145.t1 | cds | g8145.t1.CDS1 | 28783379 | 28783473 |
| chr_2 | g8145 | g8145.t1 | exon | g8145.t1.exon2 | 28783545 | 28783661 |
| chr_2 | g8145 | g8145.t1 | cds | g8145.t1.CDS2 | 28783545 | 28783661 |
| chr_2 | g8145 | g8145.t1 | exon | g8145.t1.exon3 | 28783718 | 28784063 |
| chr_2 | g8145 | g8145.t1 | cds | g8145.t1.CDS3 | 28783718 | 28784063 |
| chr_2 | g8145 | g8145.t1 | TTS | g8145.t1 | 28784238 | 28784238 |
Sequences
>g8145.t1 Gene=g8145 Length=558
ATGTCATTTGACCAGATTGATTTGGAAAGATTAAATTTGTTAAAATCTAAAATTGGTGAA
TATCCCGACTTTCCTAAAAAAGGAATAAATTTTAAAGATATCTTCACAGCATTTCGTGAT
GGAAAAGTGTGTGCCGCCACAAAAAATCTGGTTCTTAATTATGTTAAGAAAAATCATCCT
AATATTGATGCAGTTGTAGGCTTGGATGCAAGAGGGTTCCTTTTTAGCTTTCTAATCGCA
GCTGAAATGGAAATTGGATGTGTTCCGATAAGAAAAAAAGGAAAACTGCCAGGAAAGACT
GAAAAAGTTGAATATAATTTAGAGTATGGAACTGATATTTTTGAAGTTCAGAGTGACAGC
ATAAAACCTGGTCAAAAAGTTGTGATAATTGATGATCTCCTTGCAACAGGCGGCTCATTA
AAAGCTGCCAATGAATTGATCAAAAAATGCGGTGGAATAGTGGAAGCAAATATCGTAATT
TTAGAATTAAGATCAATTAATGGAAGAAAGAATCTTGATGTTCCTGTTTTTTCTTTCATT
CAGTATGCTGATGAATGA
>g8145.t1 Gene=g8145 Length=185
MSFDQIDLERLNLLKSKIGEYPDFPKKGINFKDIFTAFRDGKVCAATKNLVLNYVKKNHP
NIDAVVGLDARGFLFSFLIAAEMEIGCVPIRKKGKLPGKTEKVEYNLEYGTDIFEVQSDS
IKPGQKVVIIDDLLATGGSLKAANELIKKCGGIVEANIVILELRSINGRKNLDVPVFSFI
QYADE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g8145.t1 | CDD | cd06223 | PRTases_typeI | 50 | 178 | 0.00000 |
| 5 | g8145.t1 | Gene3D | G3DSA:3.40.50.2020 | - | 9 | 185 | 0.00000 |
| 3 | g8145.t1 | Hamap | MF_00004 | Adenine phosphoribosyltransferase [apt]. | 14 | 182 | 31.05767 |
| 2 | g8145.t1 | PANTHER | PTHR32315 | ADENINE PHOSPHORIBOSYLTRANSFERASE | 10 | 182 | 0.00000 |
| 1 | g8145.t1 | Pfam | PF00156 | Phosphoribosyl transferase domain | 48 | 152 | 0.00000 |
| 4 | g8145.t1 | SUPERFAMILY | SSF53271 | PRTase-like | 16 | 175 | 0.00000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003999 | adenine phosphoribosyltransferase activity | MF |
| GO:0009116 | nucleoside metabolic process | BP |
| GO:0006168 | adenine salvage | BP |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K00759 (adenine phosphoribosyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
