General information for g8179.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dual specificity tyrosine-phosphorylation-regulated kinase 2.
Parent gene
- The parent gene g8179 is located on chr_2: 28942271..28943002 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8179 | g8179.t3 | isoform | g8179.t3 | 28941129 | 28943002 |
| chr_2 | g8179 | g8179.t3 | exon | g8179.t3.exon1 | 28941129 | 28941176 |
| chr_2 | g8179 | g8179.t3 | cds | g8179.t3.CDS1 | 28941152 | 28941176 |
| chr_2 | g8179 | g8179.t3 | exon | g8179.t3.exon2 | 28941251 | 28941364 |
| chr_2 | g8179 | g8179.t3 | cds | g8179.t3.CDS2 | 28941251 | 28941364 |
| chr_2 | g8179 | g8179.t3 | exon | g8179.t3.exon3 | 28941442 | 28943002 |
| chr_2 | g8179 | g8179.t3 | cds | g8179.t3.CDS3 | 28941442 | 28942271 |
| chr_2 | g8179 | g8179.t3 | TSS | g8179.t3 | NA | NA |
| chr_2 | g8179 | g8179.t3 | TTS | g8179.t3 | NA | NA |
Sequences
>g8179.t3 Gene=g8179 Length=1723
TGATTTTGGGTGGAAAATATGGAATGCCCATTGATATGTGGAGTTTAGGTTGCATTTTGG
CAGAACTTTATACAGGCTTTGCAATATTGCCAGGCGAAGATGAATCAGATCAGCTTGCAT
GTATAATAGAGTTGCTAGGAATGCCACCGAAACAAGTGCTTGAAAATTCTAAACGTGCTA
AAATATTTTTTAATGCAAAAGGATATCCTCGATATTGTACGACAAAAACCTTAGAGGATG
GTTCAGTCATAATGACAGAAGGTTTTTCACGTCGTGGTATAGTTCGAGGCGCACCGGGCA
CACGAAAATTAAAGAACGCTTTAAATGGATGTGAAGATGTCTATTTTCTACAATTCATCA
GCGAATGTTTAGAATGGACTCCTGAAAAACGACTTACGCCTGAACAGGCATTACATCACT
CATGGTTCAAAAGGAGATTACCGAAGCTGCCAGGCAATGGAAATAGTAGTAATAGTAGTA
GTAATAATTATAATACCACCAAGCAAACTCATTCGCTAACAACGTCGACTAATACGCTTG
CTGATGGAGGAAAAGATTTGATTGGAGCAACAGCAGTTGGTGGTGGTTCCTCTTCATCAG
CGCTTGTGACAAATAAGGGAATTACTGCAAATTGCTTCTATTATGATAACACTCTACATC
AATTGAATATTAATCAACATAAAAATCAGCAGCAACACAACGACGAGGCAAAATCATTAC
CAGGTAATACATCATTTCATCAGCACATGCACAGTACTGTATCAAAATTGGGTGATAAAG
GATTTCAATGTGAAAGCTATCAAGATTTGTCTAACCGCAAATCTACAATGACTCTTAATC
GTTTAATGTCTTCATCAATTCATTCTGCATCAACATTATCATTAGTATCTTCATCTCATA
ACAGTACATCTCATAATAATAATAATAATCATAGTGGATCTTCATCTAGCGGCATTTCAT
CGTCGAAATTAAATTTACCGCAACTTAATTAATAATAATTAAATTTATGATGAATAAGGC
TTAAGTTAAAATGAATTGAATCATAAAAGGAAACAAATCCTATTATGTATGAAAAGAAAA
TGTCTCACACACACACACATATTGCATTTTTATGTATTTTATGCAATTTTTGCATGCAAA
AAATGTATTTCTTCAAATATATGTCTTACCTACAAGCTTTTATTCAACTTTTATTTCTGT
TTTAGCAAAAAATGAGAAGAATTAAAAATGGATTTTTTTCTATTCAACAACATTACTGAA
TTAGTAAATTAGTTAATTAAATGAAAAGAAAAGAAGTAAAAAATCTTTTTAAAATGTTAT
AAAAAATGTGAAAAGTGTCTAAAAGTTTAAGACAATGTCATGATAAAGAAATTAGATTAA
ATTACATTCTGGATAAAAATGAAAAATATTTAAAGCATTAAAAATAAAAATTTTATTTAG
AAAATATTCCTATCTCTATCTATAACGGAATTTCAAAGTTTGAAATTGAACAAATTCTTA
AAATTTTTCATAGATTAAAGATCTTAAATTTTTTTTCAATAAATGTTGCTCTTGTGCACT
CAATAAACTGCATTAAAAGCTAATAAAAATAACTTTGAATGATAACTCTAAATTATTCAA
TCCTTTTCCAGTTTATATATATCTCAGTAAAAAATTTATTATTTTTTAAAAGCGCTTTTA
AGTAGTTTTGTAATTTTTACTTGCTACAACAACAAAATATAAA
>g8179.t3 Gene=g8179 Length=322
MPIDMWSLGCILAELYTGFAILPGEDESDQLACIIELLGMPPKQVLENSKRAKIFFNAKG
YPRYCTTKTLEDGSVIMTEGFSRRGIVRGAPGTRKLKNALNGCEDVYFLQFISECLEWTP
EKRLTPEQALHHSWFKRRLPKLPGNGNSSNSSSNNYNTTKQTHSLTTSTNTLADGGKDLI
GATAVGGGSSSSALVTNKGITANCFYYDNTLHQLNINQHKNQQQHNDEAKSLPGNTSFHQ
HMHSTVSKLGDKGFQCESYQDLSNRKSTMTLNRLMSSSIHSASTLSLVSSSHNSTSHNNN
NNHSGSSSSGISSSKLNLPQLN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g8179.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 2 | 135 | 2.1E-30 |
| 6 | g8179.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 141 | 166 | - |
| 7 | g8179.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 143 | 166 | - |
| 5 | g8179.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 288 | 322 | - |
| 2 | g8179.t3 | PANTHER | PTHR24058 | DUAL SPECIFICITY PROTEIN KINASE | 1 | 171 | 1.1E-68 |
| 3 | g8179.t3 | PANTHER | PTHR24058:SF112 | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 HOMOLOG-RELATED | 1 | 171 | 1.1E-68 |
| 1 | g8179.t3 | Pfam | PF00069 | Protein kinase domain | 2 | 135 | 2.3E-12 |
| 10 | g8179.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 135 | 11.397 |
| 4 | g8179.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 2 | 137 | 1.22E-21 |
| 8 | g8179.t3 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
