General information for g8196.t16
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit alpha type-6.
Parent gene
- The parent gene g8196 is located on chr_2: 29033386..29033953 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8196 | g8196.t16 | TTS | g8196.t16 | 29032936 | 29032936 |
| chr_2 | g8196 | g8196.t16 | isoform | g8196.t16 | 29033386 | 29033953 |
| chr_2 | g8196 | g8196.t16 | exon | g8196.t16.exon1 | 29033386 | 29033796 |
| chr_2 | g8196 | g8196.t16 | cds | g8196.t16.CDS1 | 29033387 | 29033796 |
| chr_2 | g8196 | g8196.t16 | exon | g8196.t16.exon2 | 29033878 | 29033953 |
| chr_2 | g8196 | g8196.t16 | cds | g8196.t16.CDS2 | 29033878 | 29033953 |
| chr_2 | g8196 | g8196.t16 | TSS | g8196.t16 | 29034047 | 29034047 |
Sequences
>g8196.t16 Gene=g8196 Length=487
ATGTCTCGAGGCAGTAGCGCAGGATTTGATCGTCATATTACAATTTTTTCACCTGAAGGA
AGACTGTATCAAGTTGAATATGCTTTCAAAGCAATTAATCAAGAAGGAAATACTTCTGTG
GCATTAAAAGGCAAGGATGTTGCAGTTGTTGCGACTCAAAAAAAAGTTCCTGATAAGCTT
ATTGATCCCGAGACTGTTACACACTTATTTAGAATAACCAAAAGAATTGGGTGTGTTATG
ACAGGAAAGCTGGCTGATAGTAAATCGCAAGTTCAGCGGGCACAGTATGAAGCTGCTAAC
TGGAAATATAAATTTGGATATGAGATTCCAATCGATGTTCTCTGTCGTCGTATCGCGGAT
ATTGCTCAAGTTTATACACAAAATGCTGAAATGCGTCCTTTGGGATGTTCCATGATCTTG
ATTGCTTTCGATGATGAGCTTGGACCATGTGTTTTTAAAACTGATCCTGCAGGCTATTAC
TGCGGTT
>g8196.t16 Gene=g8196 Length=162
MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQEGNTSVALKGKDVAVVATQKKVPDKL
IDPETVTHLFRITKRIGCVMTGKLADSKSQVQRAQYEAANWKYKFGYEIPIDVLCRRIAD
IAQVYTQNAEMRPLGCSMILIAFDDELGPCVFKTDPAGYYCG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g8196.t16 | CDD | cd03754 | proteasome_alpha_type_6 | 8 | 162 | 1.32897E-114 |
| 6 | g8196.t16 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 1 | 162 | 1.8E-64 |
| 3 | g8196.t16 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 1 | 162 | 1.9E-88 |
| 4 | g8196.t16 | PANTHER | PTHR11599:SF110 | PROTEASOME SUBUNIT ALPHA TYPE | 1 | 162 | 1.9E-88 |
| 2 | g8196.t16 | Pfam | PF10584 | Proteasome subunit A N-terminal signature | 9 | 31 | 1.9E-14 |
| 1 | g8196.t16 | Pfam | PF00227 | Proteasome subunit | 35 | 161 | 6.3E-37 |
| 8 | g8196.t16 | ProSitePatterns | PS00388 | Proteasome alpha-type subunits signature. | 9 | 31 | - |
| 10 | g8196.t16 | ProSiteProfiles | PS51475 | Proteasome alpha-type subunit profile. | 24 | 162 | 53.767 |
| 9 | g8196.t16 | SMART | SM00948 | Proteasome_A_N_2 | 9 | 31 | 6.6E-11 |
| 5 | g8196.t16 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 8 | 162 | 3.26E-59 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019773 | proteasome core complex, alpha-subunit complex | CC |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0006511 | ubiquitin-dependent protein catabolic process | BP |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02730 (20S proteasome subunit alpha 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
