General information for g8419.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3.
Parent gene
- The parent gene g8419 is located on chr_2: 30359833..30362659 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8419 | g8419.t4 | TTS | g8419.t4 | 30358907 | 30358907 |
| chr_2 | g8419 | g8419.t4 | isoform | g8419.t4 | 30358954 | 30360641 |
| chr_2 | g8419 | g8419.t4 | exon | g8419.t4.exon1 | 30358954 | 30359144 |
| chr_2 | g8419 | g8419.t4 | cds | g8419.t4.CDS1 | 30358954 | 30359144 |
| chr_2 | g8419 | g8419.t4 | exon | g8419.t4.exon2 | 30359826 | 30360170 |
| chr_2 | g8419 | g8419.t4 | cds | g8419.t4.CDS2 | 30359826 | 30360051 |
| chr_2 | g8419 | g8419.t4 | exon | g8419.t4.exon3 | 30360232 | 30360507 |
| chr_2 | g8419 | g8419.t4 | exon | g8419.t4.exon4 | 30360570 | 30360641 |
| chr_2 | g8419 | g8419.t4 | TSS | g8419.t4 | 30360766 | 30360766 |
Sequences
>g8419.t4 Gene=g8419 Length=884
ATGTCATCAGGAAACGTTATTAATCATGTCACAATCATTGGTGCTGGCCTAATGGGCTCT
GGCATAGCTCAGGTGGCTGCATCATCCGGTCATAAAGTTACAATGGTTGAATTGGACTCT
AAACTTCTTGACAAGGCACAGAAAAACATTGAAAAAAGTTTAGAAAGAGTTGCCAAGAAA
CAATTCAAAGGCGAGGAGGATAAAATTGCCGGCTTTGTGAATGAATCAATAAGCAGAATT
TCTGGATCAACTGACTTAAATTCTGTTGTTAAAGATACTGATTTGGTCATTGAAGCAATT
GTTGAAAACCTTGAAGTTAAGCAGAAACTTTTTGGACAAATCGATGGACAAAACCATCAA
CAATTTTTGCTTCAAACACTTCATCAATTCCAATTAAAGACATTGCAAAAAGCACTTCAC
GTCTTGATAGATTCTGTGGGCTTCACTTTTTCAATCCAGTTCCAGTCATGAAGTTACTTG
AAGTTATTAGAATTCCTGAAACTTCCGACGCAACTTACAATGCAGCAATGGAATTTGGAA
AGAAAGTTGGCAAGACTTGTGTCACATGCAAAGATACACCTGGATTTATTGTCAATCGTC
TTTTGGTACCATATATGGCTGAAGCAGTACGAATGCTAGAACGAGGTGATGCTACGGCAA
GAGATATTGATACTGCCATGAAATTAGGAGCAGGCTACCCAATGGGACCTTTTGAGCTGA
GCGATTACGTTGGTTTGGACACAACAAAATTCATCTTAGATGGCTGGAGTAAAAATTATC
CAGACAATCCATTATTCAAAACAATTCCAATGTTGACAAAACTCGTTGAAGAAGGAAAAT
TAGGAATGAAAACAGGCGAAGGATTTTATAAATATCAAAAATAA
>g8419.t4 Gene=g8419 Length=138
MKLLEVIRIPETSDATYNAAMEFGKKVGKTCVTCKDTPGFIVNRLLVPYMAEAVRMLERG
DATARDIDTAMKLGAGYPMGPFELSDYVGLDTTKFILDGWSKNYPDNPLFKTIPMLTKLV
EEGKLGMKTGEGFYKYQK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g8419.t4 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 42 | 3.1E-13 |
| 7 | g8419.t4 | Gene3D | G3DSA:1.10.1040.10 | - | 46 | 137 | 1.1E-38 |
| 3 | g8419.t4 | PANTHER | PTHR43561 | - | 1 | 137 | 4.7E-65 |
| 2 | g8419.t4 | Pfam | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | 1 | 37 | 6.2E-7 |
| 1 | g8419.t4 | Pfam | PF00725 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | 39 | 136 | 5.7E-36 |
| 5 | g8419.t4 | ProSitePatterns | PS00067 | 3-hydroxyacyl-CoA dehydrogenase signature. | 36 | 60 | - |
| 4 | g8419.t4 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 38 | 138 | 1.45E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0070403 | NAD+ binding | MF |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
