General information for g8464.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as UDP-glucose 6-dehydrogenase.
Parent gene
- The parent gene g8464 is located on chr_2: 30845876..30847199 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8464 | g8464.t3 | isoform | g8464.t3 | 30845876 | 30847199 |
| chr_2 | g8464 | g8464.t3 | exon | g8464.t3.exon1 | 30845876 | 30845977 |
| chr_2 | g8464 | g8464.t3 | cds | g8464.t3.CDS1 | 30845877 | 30845977 |
| chr_2 | g8464 | g8464.t3 | exon | g8464.t3.exon2 | 30846046 | 30846214 |
| chr_2 | g8464 | g8464.t3 | cds | g8464.t3.CDS2 | 30846046 | 30846214 |
| chr_2 | g8464 | g8464.t3 | exon | g8464.t3.exon3 | 30846943 | 30847055 |
| chr_2 | g8464 | g8464.t3 | cds | g8464.t3.CDS3 | 30846943 | 30847055 |
| chr_2 | g8464 | g8464.t3 | exon | g8464.t3.exon4 | 30847112 | 30847199 |
| chr_2 | g8464 | g8464.t3 | cds | g8464.t3.CDS4 | 30847112 | 30847199 |
| chr_2 | g8464 | g8464.t3 | TSS | g8464.t3 | 30847468 | 30847468 |
| chr_2 | g8464 | g8464.t3 | TTS | g8464.t3 | NA | NA |
Sequences
>g8464.t3 Gene=g8464 Length=472
ATGATGGCGAATGGTGATTCTAATGGAACGACAATTCCTTCCTTTCCTATTTCTAAGATT
TGCTGTATTGGTGCCGGATATGTTGGCGGTCCAACATGTTCAGTAATGGCATTGATGTGT
CCTGATATAAAAGTCACGGTCGTTGATGTAAGCAAGGAAAGAATAAATCAATGGAATTCT
GAGAAATTGCCAATTTATGAGCCTGGCTTAGATGAAGTTGTAAGAAAATGCCGAGGAAGA
AATCTTTTCTTTTCAACTGACATGGAGAGTGCAATCAATGAAGCAGAGCTTATTTTCATT
TCTGTCAATACGCCAACAAAAGTGAATGGCAATGGTAAAGGTCGAGCAGCTGACTTGAAA
CATGTCGAAGGTTGCGCTCGATTGATAGCAAATATCGCACAGAGTAGTAAAATTGTCGTT
GAGAAAAGTACAGTGCCAGTGCGAGCAGCTGAAAGTATTATGCATGTATTGA
>g8464.t3 Gene=g8464 Length=157
MMANGDSNGTTIPSFPISKICCIGAGYVGGPTCSVMALMCPDIKVTVVDVSKERINQWNS
EKLPIYEPGLDEVVRKCRGRNLFFSTDMESAINEAELIFISVNTPTKVNGNGKGRAADLK
HVEGCARLIANIAQSSKIVVEKSTVPVRAAESIMHVL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g8464.t3 | Gene3D | G3DSA:3.40.50.720 | - | 14 | 157 | 0 |
| 2 | g8464.t3 | PANTHER | PTHR11374 | UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE | 17 | 156 | 0 |
| 3 | g8464.t3 | PANTHER | PTHR11374:SF34 | UDP-GLUCOSE 6-DEHYDROGENASE | 17 | 156 | 0 |
| 1 | g8464.t3 | Pfam | PF03721 | UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain | 19 | 154 | 0 |
| 4 | g8464.t3 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 19 | 155 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0003979 | UDP-glucose 6-dehydrogenase activity | MF |
| GO:0051287 | NAD binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
