Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Fumarylacetoacetase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8482 g8482.t3 TTS g8482.t3 30915586 30915586
chr_2 g8482 g8482.t3 isoform g8482.t3 30915626 30916299
chr_2 g8482 g8482.t3 exon g8482.t3.exon1 30915626 30915858
chr_2 g8482 g8482.t3 cds g8482.t3.CDS1 30915626 30915802
chr_2 g8482 g8482.t3 exon g8482.t3.exon2 30916136 30916246
chr_2 g8482 g8482.t3 exon g8482.t3.exon3 30916298 30916299
chr_2 g8482 g8482.t3 TSS g8482.t3 NA NA

Sequences

>g8482.t3 Gene=g8482 Length=346
ACCTGAAAAAGGAACACAAACAACTGTGAGTCAATCAAATTATAAATACTTGTATTGGAC
AGCATTGCAACAAATTGCTCATCATTCTGTCACTGGATGTAATTTAAATCCTGGTGATTT
ATTAGCTTCAGGAACTATTAGTGGTGAAACATCAGACTCATATGGTTCAATGTTAGAATT
AAGCTGGAAAGGAACTCGAACAATTTCACTTGGTGGAAATGAGACAAGAAAATTTCTTCA
AGATGGTGATGAAGTCATAATTCGTGGCTTCTGCAATGGCGAATACCGCATTGGTTTTGG
TGAATGTCGTGGAAAAGTTTTGCCAACAATTCCATTTGAAAATTAA

>g8482.t3 Gene=g8482 Length=58
MLELSWKGTRTISLGGNETRKFLQDGDEVIIRGFCNGEYRIGFGECRGKVLPTIPFEN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
3 g8482.t3 Gene3D G3DSA:3.90.850.10 Fumarylacetoacetate hydrolase 1 54 0
1 g8482.t3 PANTHER PTHR43069 FUMARYLACETOACETASE 1 53 0
2 g8482.t3 SUPERFAMILY SSF56529 FAH 1 52 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009072 aromatic amino acid family metabolic process BP
GO:0004334 fumarylacetoacetase activity MF
GO:0003824 catalytic activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values