General information for g8482.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Fumarylacetoacetase.
Parent gene
- The parent gene g8482 is located on chr_2: 30917143..30922428 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8482 | g8482.t8 | TTS | g8482.t8 | 30915586 | 30915586 |
| chr_2 | g8482 | g8482.t8 | isoform | g8482.t8 | 30915626 | 30917321 |
| chr_2 | g8482 | g8482.t8 | exon | g8482.t8.exon1 | 30915626 | 30915858 |
| chr_2 | g8482 | g8482.t8 | cds | g8482.t8.CDS1 | 30915855 | 30915858 |
| chr_2 | g8482 | g8482.t8 | exon | g8482.t8.exon2 | 30916132 | 30916246 |
| chr_2 | g8482 | g8482.t8 | cds | g8482.t8.CDS2 | 30916132 | 30916246 |
| chr_2 | g8482 | g8482.t8 | exon | g8482.t8.exon3 | 30916298 | 30916899 |
| chr_2 | g8482 | g8482.t8 | cds | g8482.t8.CDS3 | 30916298 | 30916899 |
| chr_2 | g8482 | g8482.t8 | exon | g8482.t8.exon4 | 30916959 | 30917176 |
| chr_2 | g8482 | g8482.t8 | cds | g8482.t8.CDS4 | 30916959 | 30917176 |
| chr_2 | g8482 | g8482.t8 | exon | g8482.t8.exon5 | 30917259 | 30917321 |
| chr_2 | g8482 | g8482.t8 | cds | g8482.t8.CDS5 | 30917259 | 30917321 |
| chr_2 | g8482 | g8482.t8 | TSS | g8482.t8 | 30917422 | 30917422 |
Sequences
>g8482.t8 Gene=g8482 Length=1231
ATGTCAACGTTTGTAGATATTCCAGTTGGAAGCGATTTTCCATTACAAAATTTACCTTAT
GGCGTCAACCGGCGCATTGGAGTTGCGATTGGCGAGAAGATTTTAGATTTAAGCGTTGTT
GCCACATTTTATCCTGAGTACGTTCAAAATGCTTTACGCGCTGATGTTTTAAATGAACTT
ATGGAACTCGGATATGATGCATGGAATGATGTTCGTCGAATTACGAAAAGTCTTCTCACC
ACTGGCTCTGATTTACATCAAAATACTGAATTGCAAAAAATTGCTCTCATTAATCAATCA
GATGCACAAATGCATTTGCCAGCAAAAATTGGCGATTATACTGATTTTTATTCTTCAATT
CATCATGCAACGAATGTTGGTGTGATGTTTAGAGGAAAGGAGAATGCACTTATGCCAAAT
TGGAAATGGCTACCAGTTGGTTATCATGGACGTGCAAGTTCTGTTGTTGTTTCTGGTACA
CCAATTAATCGACCTCTTGGTCAGACTCAACCTGTTGATGGCGCTGATCCTGTTTTTGGG
CCTTGTCGTCTATTTGATTTTGAACTTGAAATGGCATTTTTCATTGGTGGACCAGCAAAT
AAACTTGGCGAACGTGTTACAACAAAAGAAGCAGCAAAACGTGTTTTTGGTTTTGTTCTT
ATGAATGATTGGAGTGCACGTGATGTACAGAAATGGGAATATGTTCCATTAGGTCCATTT
ACTGCTAAAAATGTTGGAACTTCAATTTCACCTTGGGTTGTTACTGTTGCTGCATTGGAA
CCTTTTGCTGTTCCAAATTTCCCTCAAGATCCTAAACCATTCCCTTATTTGCAACATGAT
GAAGTTTTCAATTTTGATATCAATTTGATTGTTGACATTAAACCTGAAAAAGGAACACAA
ACAACTGTGAGTCAATCAAATTATAAATACTTGTATTGGACAGCATTGCAACAAATTGCT
CATCATTCTGTCACTGGATGTAATTTAAATCCTGGTAAGTGATTTATTAGCTTCAGGAAC
TATTAGTGGTGAAACATCAGACTCATATGGTTCAATGTTAGAATTAAGCTGGAAAGGAAC
TCGAACAATTTCACTTGGTGGAAATGAGACAAGAAAATTTCTTCAAGATGGTGATGAAGT
CATAATTCGTGGCTTCTGCAATGGCGAATACCGCATTGGTTTTGGTGAATGTCGTGGAAA
AGTTTTGCCAACAATTCCATTTGAAAATTAA
>g8482.t8 Gene=g8482 Length=333
MSTFVDIPVGSDFPLQNLPYGVNRRIGVAIGEKILDLSVVATFYPEYVQNALRADVLNEL
MELGYDAWNDVRRITKSLLTTGSDLHQNTELQKIALINQSDAQMHLPAKIGDYTDFYSSI
HHATNVGVMFRGKENALMPNWKWLPVGYHGRASSVVVSGTPINRPLGQTQPVDGADPVFG
PCRLFDFELEMAFFIGGPANKLGERVTTKEAAKRVFGFVLMNDWSARDVQKWEYVPLGPF
TAKNVGTSISPWVVTVAALEPFAVPNFPQDPKPFPYLQHDEVFNFDINLIVDIKPEKGTQ
TTVSQSNYKYLYWTALQQIAHHSVTGCNLNPGK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g8482.t8 | Gene3D | G3DSA:2.30.30.230 | Fumarylacetoacetate hydrolase | 1 | 104 | 0 |
| 8 | g8482.t8 | Gene3D | G3DSA:3.90.850.10 | Fumarylacetoacetate hydrolase | 105 | 333 | 0 |
| 3 | g8482.t8 | PANTHER | PTHR43069:SF2 | FUMARYLACETOACETASE | 2 | 332 | 0 |
| 4 | g8482.t8 | PANTHER | PTHR43069 | FUMARYLACETOACETASE | 2 | 332 | 0 |
| 1 | g8482.t8 | Pfam | PF09298 | Fumarylacetoacetase N-terminal | 16 | 107 | 0 |
| 2 | g8482.t8 | Pfam | PF01557 | Fumarylacetoacetate (FAA) hydrolase family | 113 | 332 | 0 |
| 6 | g8482.t8 | SUPERFAMILY | SSF63433 | Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 3 | 107 | 0 |
| 5 | g8482.t8 | SUPERFAMILY | SSF56529 | FAH | 109 | 332 | 0 |
| 9 | g8482.t8 | TIGRFAM | TIGR01266 | fum_ac_acetase: fumarylacetoacetase | 4 | 332 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009072 | aromatic amino acid family metabolic process | BP |
| GO:0004334 | fumarylacetoacetase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed