General information for g8572.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Peroxiredoxin 1.
Parent gene
- The parent gene g8572 is located on chr_2: 31388726..31389521 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8572 | g8572.t1 | TSS | g8572.t1 | 31387292 | 31387292 |
| chr_2 | g8572 | g8572.t1 | isoform | g8572.t1 | 31388010 | 31389300 |
| chr_2 | g8572 | g8572.t1 | exon | g8572.t1.exon1 | 31388010 | 31388140 |
| chr_2 | g8572 | g8572.t1 | cds | g8572.t1.CDS1 | 31388010 | 31388140 |
| chr_2 | g8572 | g8572.t1 | exon | g8572.t1.exon2 | 31388502 | 31388510 |
| chr_2 | g8572 | g8572.t1 | cds | g8572.t1.CDS2 | 31388502 | 31388510 |
| chr_2 | g8572 | g8572.t1 | exon | g8572.t1.exon3 | 31388578 | 31388660 |
| chr_2 | g8572 | g8572.t1 | cds | g8572.t1.CDS3 | 31388578 | 31388660 |
| chr_2 | g8572 | g8572.t1 | exon | g8572.t1.exon4 | 31388728 | 31389006 |
| chr_2 | g8572 | g8572.t1 | cds | g8572.t1.CDS4 | 31388728 | 31389006 |
| chr_2 | g8572 | g8572.t1 | exon | g8572.t1.exon5 | 31389209 | 31389300 |
| chr_2 | g8572 | g8572.t1 | cds | g8572.t1.CDS5 | 31389209 | 31389300 |
| chr_2 | g8572 | g8572.t1 | TTS | g8572.t1 | 31389517 | 31389517 |
Sequences
>g8572.t1 Gene=g8572 Length=594
ATGGCACCAGCTCTTCAGAAACCAGCTCCAGAATTCAAAGCAACAGCCGTTGTTAACGGA
AGCTTCAAGGAAATCAGCTTGGCTGACTACAAAGGCAAATATCTTGTTCTTTTCTTCTAT
CCATTGGACTTTACATTTGTCTGTCCAACTGAAATTATTGCATTCAGCGAGCGTGTTGAT
GACTTCAGAAAAATCAATTGTGAAATTGTTGGTGTCTCAACTGATTCACACTTCACACAT
CTTGCTTGGATCAACACACCCCGTAAAGAAGGTGGCTTAGGAAACATCACTTATCCATTG
TTGGCTGACAAATCAATGGAAATCTCAAAAGCTTATGGTGTTTTGGATGAAGCTTCAGGT
ATTCCTTTCAGAGGACTATTTATTATTGATGGCAATCAAAATCTTCGTCAAATTACCATG
AATGACTTGCCTGTTGGACGTAGTGTTGATGAAACTCTTCGTTTGGTTGAGGCATTCCAA
TATACTGATACTCATGGTGAAGTTTGCCCAGCAGGGTGGTCTAAGGACAAGAACAGCGCC
ACAATGGTTCCAGATCCCACACGCTCCAAGGATTATTTTAGAGCTGTCAATTAA
>g8572.t1 Gene=g8572 Length=197
MAPALQKPAPEFKATAVVNGSFKEISLADYKGKYLVLFFYPLDFTFVCPTEIIAFSERVD
DFRKINCEIVGVSTDSHFTHLAWINTPRKEGGLGNITYPLLADKSMEISKAYGVLDEASG
IPFRGLFIIDGNQNLRQITMNDLPVGRSVDETLRLVEAFQYTDTHGEVCPAGWSKDKNSA
TMVPDPTRSKDYFRAVN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g8572.t1 | CDD | cd03015 | PRX_Typ2cys | 5 | 176 | 0.000 |
| 6 | g8572.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 197 | 0.000 |
| 3 | g8572.t1 | PANTHER | PTHR10681:SF154 | THIOREDOXIN-LIKE FOLD | 7 | 194 | 0.000 |
| 4 | g8572.t1 | PANTHER | PTHR10681 | THIOREDOXIN PEROXIDASE | 7 | 194 | 0.000 |
| 8 | g8572.t1 | PIRSF | PIRSF000239 | AHPC | 1 | 196 | 0.000 |
| 2 | g8572.t1 | Pfam | PF00578 | AhpC/TSA family | 6 | 137 | 0.000 |
| 1 | g8572.t1 | Pfam | PF10417 | C-terminal domain of 1-Cys peroxiredoxin | 158 | 190 | 0.000 |
| 7 | g8572.t1 | ProSiteProfiles | PS51352 | Thioredoxin domain profile. | 3 | 161 | 17.274 |
| 5 | g8572.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 4 | 194 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016209 | antioxidant activity | MF |
| GO:0055114 | NA | NA |
| GO:0051920 | peroxiredoxin activity | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03386 (peroxiredoxin 2/4)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
