General information for g8608.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Cyclin-dependent kinase 14.
Parent gene
- The parent gene g8608 is located on chr_2: 31758306..31760969 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8608 | g8608.t3 | TSS | g8608.t3 | 31757067 | 31757067 |
| chr_2 | g8608 | g8608.t3 | isoform | g8608.t3 | 31757349 | 31759549 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon1 | 31757349 | 31757418 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS1 | 31757349 | 31757418 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon2 | 31758310 | 31758387 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS2 | 31758310 | 31758387 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon3 | 31758691 | 31758840 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS3 | 31758691 | 31758840 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon4 | 31758922 | 31759121 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS4 | 31758922 | 31759121 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon5 | 31759210 | 31759301 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS5 | 31759210 | 31759301 |
| chr_2 | g8608 | g8608.t3 | exon | g8608.t3.exon6 | 31759375 | 31759549 |
| chr_2 | g8608 | g8608.t3 | cds | g8608.t3.CDS6 | 31759375 | 31759549 |
| chr_2 | g8608 | g8608.t3 | TTS | g8608.t3 | NA | NA |
Sequences
>g8608.t3 Gene=g8608 Length=765
ATGTATTCTACGATGGATAAACAATCATCGAGTAGTAACAATTTGAAAATGACTAATACT
TCAGCTACGGGTGTCACAATGCGTGAGAAAAAAAGTGGAGCTCTGCAGAAATTAAAAAAG
CGATTATCACATAGCTTTGGAAGATTATCAATATCAAGAGAAGATAATGATGAGTCAAAT
AATCACCATAGTCAAAACAGAAATAATAGTAAAATGCCATACAATAATGGATATTCCGAA
GAATATTTAGATCGCTTGGAGAAAAATGGTAATATTCAGGCTGATAACAAAGCTTACAAT
TGGTCTGGTAATCATAATCATGGTCAAGTTCATAGGCAATTATCGGTATCATCAGACAGT
AAGCTTCTCGATGATGATATAAGAGAAGAAACGCGTGTGATAATGAGACCCAAAAAAATT
CCACCGCGACCTAAGTCAGAAGTGTTCTTAAATAAGCACGATTCTCATCCGAGAAGGAAA
CGATTCAGTGCATTTGGGGGCGACTCGCCATTTGGTAAATCGGAGGCATATGTTAAACTG
GAGCAACTTGGCGAGGGCTCATATGCAACAGTATTCAAGGGTTTTAGCAACCTCACAAAT
CAAGTCGTTGCGCTAAAAGAAATAAGACTACAAGAGGAAGAAGGTGCACCATTCACAGCC
ATTCGAGAAGCATCTCTTTTAAAAGAATTGAAACATGCCAATATTGTAACGCTTCATGAT
ATTGTTCACACAAGAGAAACATTGACATTTGTATTTGAATATGTG
>g8608.t3 Gene=g8608 Length=255
MYSTMDKQSSSSNNLKMTNTSATGVTMREKKSGALQKLKKRLSHSFGRLSISREDNDESN
NHHSQNRNNSKMPYNNGYSEEYLDRLEKNGNIQADNKAYNWSGNHNHGQVHRQLSVSSDS
KLLDDDIREETRVIMRPKKIPPRPKSEVFLNKHDSHPRRKRFSAFGGDSPFGKSEAYVKL
EQLGEGSYATVFKGFSNLTNQVVALKEIRLQEEEGAPFTAIREASLLKELKHANIVTLHD
IVHTRETLTFVFEYV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g8608.t3 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 174 | 255 | 1.3E-31 |
| 7 | g8608.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 27 | - |
| 8 | g8608.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 75 | - |
| 6 | g8608.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 47 | 64 | - |
| 2 | g8608.t3 | PANTHER | PTHR24056:SF189 | ECDYSONE-INDUCED PROTEIN 63E, ISOFORM N | 129 | 255 | 1.6E-45 |
| 3 | g8608.t3 | PANTHER | PTHR24056 | CELL DIVISION PROTEIN KINASE | 129 | 255 | 1.6E-45 |
| 1 | g8608.t3 | Pfam | PF00069 | Protein kinase domain | 177 | 255 | 3.6E-16 |
| 5 | g8608.t3 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 183 | 206 | - |
| 10 | g8608.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 177 | 255 | 14.097 |
| 4 | g8608.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 174 | 255 | 2.11E-19 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
