General information for g8670.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein farnesyltransferase subunit beta.
Parent gene
- The parent gene g8670 is located on chr_2: 32175512..32177168 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8670 | g8670.t1 | isoform | g8670.t1 | 32170289 | 32175802 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon1 | 32170289 | 32170378 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS1 | 32170289 | 32170378 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon2 | 32170436 | 32171655 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS2 | 32170436 | 32171655 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon3 | 32171987 | 32172000 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS3 | 32171987 | 32172000 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon4 | 32173919 | 32174200 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS4 | 32173919 | 32174200 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon5 | 32174264 | 32174481 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS5 | 32174264 | 32174481 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon6 | 32174618 | 32174860 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS6 | 32174618 | 32174860 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon7 | 32175085 | 32175450 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS7 | 32175085 | 32175450 |
| chr_2 | g8670 | g8670.t1 | exon | g8670.t1.exon8 | 32175512 | 32175802 |
| chr_2 | g8670 | g8670.t1 | cds | g8670.t1.CDS8 | 32175512 | 32175802 |
| chr_2 | g8670 | g8670.t1 | TTS | g8670.t1 | 32176243 | 32176243 |
| chr_2 | g8670 | g8670.t1 | TSS | g8670.t1 | NA | NA |
Sequences
>g8670.t1 Gene=g8670 Length=2724
ATGGAAGAAGGACAAATAAGAAACTTTAGTGAAATTAAAACAGAAAAGTTTGATGATGAA
AATCTTGAAACAATAACGTCAAAAGAACAGATAAAAGTTGAGAATCTAGTCGAAAAATGC
TTTGATCGATTTGAACAATTAGCTGCACTTGACCCAACGATGCCATATTTTTATAGAAAA
GAACATATAAGATTTCTTGAAAGATCTCTGCGATTTTTATCGACTGGTTATGAATGTTTA
GATGCATCACGACCTTGGTTAGTTTACTGGATCTTACAATCAGCTCATTGTCTAAACTTT
AAATTCTCACATGAAGTGCTCACTGATGTTATTCACTTTCTCAAAAATTGCCGACATCCT
CATGGCGGTTTTGCAGGAGGTCCGAATCAATTTCCTCACTTGGCACCAACATATGCTGCA
GTTCTTAGTCTCTGTTTGATTGAAACGGAAGAAGCTTTTGAAACAATCGATTATGAAGGC
ATTAAAAATTTCTTATGGAGTGTTAGAACTGAAAATGGAGCATTTCGAATGCATGTTGAT
GGAGAAATTGATGTAAGAGGAGCTTATTGCGCAATTGTAGTTGCACGTTTAAGTGGTTTG
AGTCCAAACAATAAATTATTTGAAGGAACGGCTCAATGGATTGCATCTTGTCAAACATAT
GAAGGAGGATTCGGCGGAACACCAAATTTAGAAGCTCATGGTGGATATTCATTTTGTGCC
GCAGCTGCTTTAGCTCTTCTTGGCAATACATCGAATGTTAATTTGAGAACACTACTAAGA
TGGGCAGTAAATAGACAAATGCGTTATGAAGGTGGTTTTCAAGGACGAACGAATAAACTT
GTTGATGGATGCTATTCATTTTGGCAAGGCGCTCTTGTGCAAGTCATTCAAATGTTGATT
GAAAAAAATACATGCACTGATGGATATACAATCAATATAGATGAACTTCTTTTTAATCGA
ACAGCTCTTCAAGAATATATATTGATTTGTTGTCAAAAACCAAATGGTGGTTTGATCGAT
AAACCTGGAAAACCTGAAGATCTTTATCATACATGTTATACACTTAGTGGACTATCAATT
GCTCAAAATTTTAATTCTACTAAACAACCAGTTATTATTGGTAATTCAGAGACAAACGAA
GTACTTGCCACTCATCCACTTTACAATATCTCACCGAAATCTGTCATGAAGGCATACATT
TATGCTCAACAACATCTAATTGAAAAAGATGAAGATTTAATTGGATTTAAAGATCAGTGT
GAAAACAGCGAGAAAGAAGCAAATGAAACTGATCAAAATAACGACCAATACAAGGAAGCA
CCGGGTCCTGAAATTGGCCAGCCGCCCTTATCAAATCAACGTGTCATGTCGGTTCGCTAT
TCTGCGGATTCTACTATTGTCGCTGTCTCATCTACATCAACCGACTTTAGTGCGATGAAC
AATAATAATAATGACATCATCGCCTCGTCTGGCCAAGCTTATCATCAAATGAATAGTATG
AGCAGTAACAACATAGGAGGAAAGACTCAAGCGGTGATCGATAACGGAATAAGCCAAAAA
CAACATCAACAACAGGGCAGGCCAAAAATGGAAGGAACTCCGGATGCTAAAAATGCATCA
TGTATGAGTTCTAATTTTAACATCTCTACCAACATAAACAATAACAATATTCAAGAACAA
CAACAACAACATAGCAATTCCAACAACATGGCTCATCATCATCTTTTAAATGCTAGTGCT
CAAGACTTATTTTCACAATTACACGAAGCACTTTCATTAGAGCCCAAATATCAACCGAAC
TTATTTTTACCTCAGCAATCAAATGATGGTGAAATAACAATCGGTACAAGAGACGGTGCT
GCACATGTATTAAGATGCCTGAAAGTCTGGTATGATTTGCCAAATGATGTCCTTTTTAAT
GCAGTTAATGCAGTTGATCGATTTTTAACCAAAATGAAAGTACGACCAAAACATATGGCT
TGCATTTCTGTTGGATCTTTGCATTTGGCTATCAAACAATTGGGACTTGAAGGCATTGAT
ACAGAAGATTTAGTTGCGATTTCTCAATGTCGTTGCACTGCACGTGATCTTGAAAGAATG
ACAGAAATTATTCACAATAAATTGGGAGTTCAAATGAATTCAGCACCTATCACTGGTTTG
ACCTTCATTCGACTCTTTTACTACATCTTCCGTTTGACCGCCATCGAATTGGACCTTCAA
AATTTTTATGATTCCTCAATTGTCTTATCTGATCTCGAACAAAGAATGGAAATTTTGGCA
TGTGATGCAAATTGTTCCAGCATTCGTCCATCTGAATTAGCTCTCGTTGCAATTTGTACT
CAAATGGATGCTTGCATCAGTCAACTTGAAGCAGGATCACATCAAATTCATGGTTTGGTT
GATTATGCCATTCAATTGCAAAAATTATGCAGAATTCCTGACTCGTCATTCTTTCACACT
CATGAATCAGTCGTAAGAATTCTCTCCAACTACAATGGTCAACAAAAAATGCCCTATCGT
CAACGTCTTGTATGGAAATTAAGTTCTAGAACATTGAGATCATTGAGGCCGACAGATAAA
TTGAAAGTCTCCTCATATTTGCCAACTATTGAAGAAGACAATAATTCACAACTTCGTTAT
AGAACAGGAAGTGTTTCATCAGAAGATGGCTCAGAAGAAGATTGGCCAACATCACCAATT
GTCGCCGTTTGTGAAGAATGCTAA
>g8670.t1 Gene=g8670 Length=907
MEEGQIRNFSEIKTEKFDDENLETITSKEQIKVENLVEKCFDRFEQLAALDPTMPYFYRK
EHIRFLERSLRFLSTGYECLDASRPWLVYWILQSAHCLNFKFSHEVLTDVIHFLKNCRHP
HGGFAGGPNQFPHLAPTYAAVLSLCLIETEEAFETIDYEGIKNFLWSVRTENGAFRMHVD
GEIDVRGAYCAIVVARLSGLSPNNKLFEGTAQWIASCQTYEGGFGGTPNLEAHGGYSFCA
AAALALLGNTSNVNLRTLLRWAVNRQMRYEGGFQGRTNKLVDGCYSFWQGALVQVIQMLI
EKNTCTDGYTINIDELLFNRTALQEYILICCQKPNGGLIDKPGKPEDLYHTCYTLSGLSI
AQNFNSTKQPVIIGNSETNEVLATHPLYNISPKSVMKAYIYAQQHLIEKDEDLIGFKDQC
ENSEKEANETDQNNDQYKEAPGPEIGQPPLSNQRVMSVRYSADSTIVAVSSTSTDFSAMN
NNNNDIIASSGQAYHQMNSMSSNNIGGKTQAVIDNGISQKQHQQQGRPKMEGTPDAKNAS
CMSSNFNISTNINNNNIQEQQQQHSNSNNMAHHHLLNASAQDLFSQLHEALSLEPKYQPN
LFLPQQSNDGEITIGTRDGAAHVLRCLKVWYDLPNDVLFNAVNAVDRFLTKMKVRPKHMA
CISVGSLHLAIKQLGLEGIDTEDLVAISQCRCTARDLERMTEIIHNKLGVQMNSAPITGL
TFIRLFYYIFRLTAIELDLQNFYDSSIVLSDLEQRMEILACDANCSSIRPSELALVAICT
QMDACISQLEAGSHQIHGLVDYAIQLQKLCRIPDSSFFHTHESVVRILSNYNGQQKMPYR
QRLVWKLSSRTLRSLRPTDKLKVSSYLPTIEEDNNSQLRYRTGSVSSEDGSEEDWPTSPI
VAVCEEC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g8670.t1 | CDD | cd02893 | FTase | 59 | 361 | 8.26669E-157 |
| 15 | g8670.t1 | CDD | cd00043 | CYCLIN | 631 | 705 | 2.35696E-7 |
| 14 | g8670.t1 | Coils | Coil | Coil | 420 | 440 | - |
| 13 | g8670.t1 | Gene3D | G3DSA:1.50.10.20 | - | 2 | 423 | 2.9E-146 |
| 11 | g8670.t1 | Gene3D | G3DSA:1.10.472.10 | - | 587 | 802 | 6.5E-19 |
| 12 | g8670.t1 | Gene3D | G3DSA:1.10.472.10 | - | 600 | 715 | 6.5E-19 |
| 18 | g8670.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 517 | 537 | - |
| 7 | g8670.t1 | PANTHER | PTHR11774 | GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT | 12 | 404 | 7.0E-146 |
| 8 | g8670.t1 | PANTHER | PTHR11774:SF6 | PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA | 12 | 404 | 7.0E-146 |
| 2 | g8670.t1 | Pfam | PF00432 | Prenyltransferase and squalene oxidase repeat | 110 | 147 | 9.2E-8 |
| 6 | g8670.t1 | Pfam | PF00432 | Prenyltransferase and squalene oxidase repeat | 156 | 196 | 0.016 |
| 5 | g8670.t1 | Pfam | PF00432 | Prenyltransferase and squalene oxidase repeat | 209 | 248 | 2.0E-11 |
| 4 | g8670.t1 | Pfam | PF00432 | Prenyltransferase and squalene oxidase repeat | 256 | 289 | 1.9E-5 |
| 3 | g8670.t1 | Pfam | PF00432 | Prenyltransferase and squalene oxidase repeat | 319 | 361 | 8.5E-5 |
| 1 | g8670.t1 | Pfam | PF00134 | Cyclin, N-terminal domain | 596 | 712 | 2.0E-10 |
| 17 | g8670.t1 | SMART | SM00385 | cyclin_7 | 622 | 706 | 4.5E-5 |
| 10 | g8670.t1 | SUPERFAMILY | SSF48239 | Terpenoid cyclases/Protein prenyltransferases | 12 | 405 | 2.16E-121 |
| 9 | g8670.t1 | SUPERFAMILY | SSF47954 | Cyclin-like | 588 | 713 | 3.4E-20 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005965 | protein farnesyltransferase complex | CC |
| GO:0003824 | catalytic activity | MF |
| GO:0018343 | protein farnesylation | BP |
KEGG
Orthology
- This transcript has been annotated with K05954 (protein farnesyltransferase subunit beta)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
