General information for g8739.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase.
Parent gene
- The parent gene g8739 is located on chr_2: 32739772..32741208 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8739 | g8739.t7 | TTS | g8739.t7 | 32738988 | 32738988 |
| chr_2 | g8739 | g8739.t7 | isoform | g8739.t7 | 32739452 | 32741208 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon1 | 32739452 | 32740321 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS1 | 32739454 | 32740321 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon2 | 32740401 | 32740438 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS2 | 32740401 | 32740438 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon3 | 32740505 | 32740789 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS3 | 32740505 | 32740789 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon4 | 32740855 | 32740905 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS4 | 32740855 | 32740905 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon5 | 32740983 | 32741096 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS5 | 32740983 | 32741096 |
| chr_2 | g8739 | g8739.t7 | exon | g8739.t7.exon6 | 32741152 | 32741208 |
| chr_2 | g8739 | g8739.t7 | cds | g8739.t7.CDS6 | 32741152 | 32741208 |
| chr_2 | g8739 | g8739.t7 | TSS | g8739.t7 | 32741467 | 32741467 |
Sequences
>g8739.t7 Gene=g8739 Length=1415
ATGGAATCAGAAGATACAGAAAATAATAAAAATTCTTCAATGTTTTATTTTGGACAAGAT
GACGAGGAGGATAGCGATGATTATGAGACAGTTAAAGTCATTGTTGGCGTGTGTGCTATG
CAAAAAAAGTCACAAAGCAAACCTATGAAAGAGATATTGGAGAGATTACAGGAATTTGAA
TTTATTAAGATATACATTTTTCCTGAAGAAGTCATACTCAAGGAGGAGATTGAGAACTGG
GCTATAGTTGATTGTTTAATATCATTTCATTCAAAAGGTTTTCCATTAGAAAAAGCCATA
CGTTATGCACAAATGCGAAACTGTTATGTTCTCAATAATTTAAAAATGCAATTTGACATT
CAAGACAGACGCAAAGTTTATGCAATTTTAGAAAGAGAAGGAATTGAAATTCCACGTTAT
GCTGTCCTTGACCGCGATTCAAGCGAGCCCCATGAGCTTGTAGAATCAGAAGACCATGTT
GAAATTAATGGCATTACATTTAATAAGCCGTTTGTAGAGAAGCCAGTATCAGCTGAAGAT
CATAATATATACATTTATTATCCAACGTCGGCTGGTGGAGGCTCACAAAGATTATTTAGA
AAAATTGGCAGTAGATCATCTGTTTATAGTCCAGAGTCGCGTGTAAGAAAAAGTGGATCA
TTTATTTATGAGGATTTTCAAGCTACAGATGGAACTGATGTCAAAGTTTATACTGTTGGT
CCAGATTATGCACATGCTGAAGCACGTAAGAGTCCAGCTTTAGATGGTAAAGTTGAACGT
GATAGTGAAGGAAAAGAGATAAGATATCCAGTGATTTTATCTAATGCTGAAAAACTAATT
GCAAGAAAAGTTTGTCTCGCTTTTAAACAAACTGTTTGTGGTTTTGACTTGCTAAGGGCG
AATGGAAAATCTTATGTTTGTGATGTGAATGGATTTAGTTTTGTTAAAAATTCAAACAAA
TATTATGATGACACTGCGAAAATTTTGGGAAGTTTAATTTTAAGAAATTTAGCCCCAAAA
ATGAACATCCCACTGCCAATGAATTTTAATTTCTTTGATGATCCACCAGTTGTTCCAACT
ACGGTTGGTAAAATGATGGAACTTAGATGTGTTGTTGCTGTCATTCGTCATGGAGATAGA
ACACCAAAGCAAAAAATGAAAGTGGAAGTTCGACATCAAAAGTTTTTTGAAATTTTTGAA
AAATATGATGGCTATAAGAAACTTTCAATTAAATTAAAAAAGCCAAAGCAACTTCAAGAA
ATTTTAGACATTTCTCGTTATTTGTTAAGTGAAATTCAAGCTAATCCTGGATTTGATAAA
GAATTAGAAGAAAAGCAAGCAAAATTAGAGCAACTTAAAAGCGTATTAGAAATGTATGGG
CATTTTAGTGGAATAAATCGAAAAGTTCAGATGAA
>g8739.t7 Gene=g8739 Length=471
MESEDTENNKNSSMFYFGQDDEEDSDDYETVKVIVGVCAMQKKSQSKPMKEILERLQEFE
FIKIYIFPEEVILKEEIENWAIVDCLISFHSKGFPLEKAIRYAQMRNCYVLNNLKMQFDI
QDRRKVYAILEREGIEIPRYAVLDRDSSEPHELVESEDHVEINGITFNKPFVEKPVSAED
HNIYIYYPTSAGGGSQRLFRKIGSRSSVYSPESRVRKSGSFIYEDFQATDGTDVKVYTVG
PDYAHAEARKSPALDGKVERDSEGKEIRYPVILSNAEKLIARKVCLAFKQTVCGFDLLRA
NGKSYVCDVNGFSFVKNSNKYYDDTAKILGSLILRNLAPKMNIPLPMNFNFFDDPPVVPT
TVGKMMELRCVVAVIRHGDRTPKQKMKVEVRHQKFFEIFEKYDGYKKLSIKLKKPKQLQE
ILDISRYLLSEIQANPGFDKELEEKQAKLEQLKSVLEMYGHFSGINRKVQM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g8739.t7 | Gene3D | G3DSA:3.40.50.11950 | - | 35 | 339 | 2.6E-156 |
| 9 | g8739.t7 | Gene3D | G3DSA:3.30.470.100 | - | 114 | 313 | 2.6E-156 |
| 8 | g8739.t7 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 24 | - |
| 3 | g8739.t7 | PANTHER | PTHR12750:SF10 | INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 | 4 | 471 | 3.4E-249 |
| 4 | g8739.t7 | PANTHER | PTHR12750 | DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE | 4 | 471 | 3.4E-249 |
| 1 | g8739.t7 | Pfam | PF18086 | Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain | 33 | 122 | 3.2E-38 |
| 2 | g8739.t7 | Pfam | PF00328 | Histidine phosphatase superfamily (branch 2) | 367 | 469 | 1.1E-22 |
| 7 | g8739.t7 | ProSitePatterns | PS00616 | Histidine acid phosphatases phosphohistidine signature. | 368 | 382 | - |
| 6 | g8739.t7 | SUPERFAMILY | SSF56059 | Glutathione synthetase ATP-binding domain-like | 125 | 313 | 2.83E-6 |
| 5 | g8739.t7 | SUPERFAMILY | SSF53254 | Phosphoglycerate mutase-like | 352 | 467 | 6.39E-10 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000829 | inositol heptakisphosphate kinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed