General information for g876.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as UDP-glucuronosyltransferase 1-10.
Parent gene
- The parent gene g876 is located on chr_3: 6617556..6626867 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g876 | g876.t12 | TSS | g876.t12 | 6616059 | 6616059 |
| chr_3 | g876 | g876.t12 | isoform | g876.t12 | 6616086 | 6617929 |
| chr_3 | g876 | g876.t12 | exon | g876.t12.exon1 | 6616086 | 6616320 |
| chr_3 | g876 | g876.t12 | exon | g876.t12.exon2 | 6616376 | 6616652 |
| chr_3 | g876 | g876.t12 | exon | g876.t12.exon3 | 6616843 | 6617410 |
| chr_3 | g876 | g876.t12 | cds | g876.t12.CDS1 | 6616875 | 6617410 |
| chr_3 | g876 | g876.t12 | exon | g876.t12.exon4 | 6617470 | 6617929 |
| chr_3 | g876 | g876.t12 | cds | g876.t12.CDS2 | 6617470 | 6617929 |
| chr_3 | g876 | g876.t12 | TTS | g876.t12 | 6617993 | 6617993 |
Sequences
>g876.t12 Gene=g876 Length=1540
ATGAAGCTCTCAATTGCTTTGATTCTTCTCTTTGTTAATGGAATTCTTGGTTTTAAAGTC
TTAGGAATAATTCCTTTTGGTAGCAAATCACATTTTGCTATTGGTCATTCAATCTTGAAA
AGTTTAGCTGAAGCTGGACATGAAGTTACAGCCATTTCACCTTATCCATTAAAAAAACCA
ATGAAAAATTACAAAGATATCAGCACAGAGGATTATATTGAATTTTTTTTTAAGAATAAT
GCTGCAAATATGTTTGATTTTGAGAACAGTTTCTTTGTCAATAAAATAATGGAATTGATT
GTAATTCATTGGATGGGAACTGAACTTGTTGAATATTATGTAAATCATCCAAAGGTCGTC
GAGTTTCTTAAAACTAATGAGAAGTTTGATATTTGTGTTATTGAAGTTTTTAACTTTGAT
GCATTACTTGGAATTGCTGAACATGTGGGCTGCAAAGTTGTTTCTTATGTCACTTGTGGT
ATTGTAAAGTGGACTGATGATATTTCTGGACTTACCAAAACATTACGTTGAATACACTGA
TCGAATGACATTTAAACAACGACTAATAAATACAGTTTACTCACACATTGAAGATTTTAT
TTATGGACAAATTGTAAAGAAAAATCAAAAAAGACTTTATGAGAAATATTTCCCTAATGC
AATCAAGACTTTTGATGAAATGTATAAAAATACTTCAATACTTTTCATGAATACTCACAT
TTCAACATCGACAGCTCGACCTTATATGCCAATTCAAGTTGAAATTGGAGGGATTCATAT
TCAGCCGGCTAAACCACTGCCCAAAGATATACAAGAATTTTTAGACTCAGCAACTGATGG
TGCAATCATTTTTTCAATGGGTTCAGTTATTAAGTCGAATCAATGGCCAGTTGATAAACG
TGAAGCATTTATAAAAATTTTTAGCAAATTAAAACAGAAAATAATTTGGAAATATGAAAA
TGACACATTGCCTAATAAACCTGACAATGTTATGATCAGTTCATGGATGCCACAAAGAGA
CATTTTAGCTCATCCTAATGTTAAAGTATTCATTACACATGGGGGACTGGGAGGCACAAC
TGAAGCTCTTGTTGAAGGAGTTCCTATTCTAGGCTTGCCTATATTTGGTGATCAAAAAAT
GAATATGGTTAAAGCAGTTACTCGAGGCTATGGTTTGCAAGTTTATTTTAAAGACATTTC
TGAAGAAACTATTGAATCTGCACTTAAAGAATTATTGAACAATCCAATGTACAAAGAAAA
TGCAAAAATTATTTCAAAACGCTTTAATGATCGACCAATGACACCACAACAATCAGTAGT
TTATTGGACTGAATATGTTCATAGACATGACGGAGCGCCACACTTGAAAGCTGCTGCAAT
TGATTTGGATTTTATCGCATTTCACATGATTGATATTTATGCTGTTTTAATATTCATCAC
AATTTTAATTATTTATATTGATTATTTAATTCTCAAATGGCTTTTTAGAAAATGTTTTGG
AAAATCAAAGAAAATAGATAAAAAAGATAAGAAAAATTAG
>g876.t12 Gene=g876 Length=331
MTFKQRLINTVYSHIEDFIYGQIVKKNQKRLYEKYFPNAIKTFDEMYKNTSILFMNTHIS
TSTARPYMPIQVEIGGIHIQPAKPLPKDIQEFLDSATDGAIIFSMGSVIKSNQWPVDKRE
AFIKIFSKLKQKIIWKYENDTLPNKPDNVMISSWMPQRDILAHPNVKVFITHGGLGGTTE
ALVEGVPILGLPIFGDQKMNMVKAVTRGYGLQVYFKDISEETIESALKELLNNPMYKENA
KIISKRFNDRPMTPQQSVVYWTEYVHRHDGAPHLKAAAIDLDFIAFHMIDIYAVLIFITI
LIIYIDYLILKWLFRKCFGKSKKIDKKDKKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g876.t12 | CDD | cd03784 | GT1_Gtf-like | 30 | 261 | 3.55936E-57 |
| 5 | g876.t12 | Gene3D | G3DSA:3.40.50.2000 | Glycogen Phosphorylase B; | 80 | 249 | 8.6E-48 |
| 2 | g876.t12 | PANTHER | PTHR48043 | EG:EG0003.4 PROTEIN-RELATED | 1 | 313 | 2.2E-103 |
| 3 | g876.t12 | PANTHER | PTHR48043:SF59 | UDP-GLUCURONOSYLTRANSFERASE | 1 | 313 | 2.2E-103 |
| 1 | g876.t12 | Pfam | PF00201 | UDP-glucoronosyl and UDP-glucosyl transferase | 1 | 323 | 1.5E-79 |
| 7 | g876.t12 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 290 | - |
| 8 | g876.t12 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 291 | 314 | - |
| 6 | g876.t12 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 315 | 331 | - |
| 11 | g876.t12 | ProSitePatterns | PS00375 | UDP-glycosyltransferases signature. | 154 | 197 | - |
| 4 | g876.t12 | SUPERFAMILY | SSF53756 | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 271 | 1.29E-80 |
| 10 | g876.t12 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 291 | 313 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008194 | UDP-glycosyltransferase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed