General information for g876.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as UDP-glucuronosyltransferase 1-8.
Parent gene
- The parent gene g876 is located on chr_3: 6617556..6626867 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g876 | g876.t8 | TSS | g876.t8 | 6616059 | 6616059 |
| chr_3 | g876 | g876.t8 | isoform | g876.t8 | 6616086 | 6617929 |
| chr_3 | g876 | g876.t8 | exon | g876.t8.exon1 | 6616086 | 6616320 |
| chr_3 | g876 | g876.t8 | exon | g876.t8.exon2 | 6616410 | 6616652 |
| chr_3 | g876 | g876.t8 | cds | g876.t8.CDS1 | 6616429 | 6616652 |
| chr_3 | g876 | g876.t8 | exon | g876.t8.exon3 | 6616823 | 6617410 |
| chr_3 | g876 | g876.t8 | cds | g876.t8.CDS2 | 6616823 | 6617410 |
| chr_3 | g876 | g876.t8 | exon | g876.t8.exon4 | 6617470 | 6617929 |
| chr_3 | g876 | g876.t8 | cds | g876.t8.CDS3 | 6617470 | 6617929 |
| chr_3 | g876 | g876.t8 | TTS | g876.t8 | 6617993 | 6617993 |
Sequences
>g876.t8 Gene=g876 Length=1526
ATGAAGCTCTCAATTGCTTTGATTCTTCTCTTTGTTAATGGAATTCTTGGTTTTAAAGTC
TTAGGAATAATTCCTTTTGGTAGCAAATCACATTTTGCTATTGGTCATTCAATCTTGAAA
AGTTTAGCTGAAGCTGGACATGAAGTTACAGCCATTTCACCTTATCCATTAAAAAAACCA
ATGAAAAATTACAAAGATATCAGCACAGAGGATTATATTGAATTTTTTTTTAAGATTTCT
TTGTCAATAAAATAATGGAATTGATTGTAATTCATTGGATGGGAACTGAACTTGTTGAAT
ATTATGTAAATCATCCAAAGGTCGTCGAGTTTCTTAAAACTAATGAGAAGTTTGATATTT
GTGTTATTGAAGTTTTTAACTTTGATGCATTACTTGGAATTGCTGAACATGTGGGCTGCA
AAGTTGTTTCTTATGTCACTTGTGGTATTGTAAAGTGGACTGATGATATTTCTGGACTTG
TTTCACCACCATCATATGTACCAAAACATTACGTTGAATACACTGATCGAATGACATTTA
AACAACGACTAATAAATACAGTTTACTCACACATTGAAGATTTTATTTATGGACAAATTG
TAAAGAAAAATCAAAAAAGACTTTATGAGAAATATTTCCCTAATGCAATCAAGACTTTTG
ATGAAATGTATAAAAATACTTCAATACTTTTCATGAATACTCACATTTCAACATCGACAG
CTCGACCTTATATGCCAATTCAAGTTGAAATTGGAGGGATTCATATTCAGCCGGCTAAAC
CACTGCCCAAAGATATACAAGAATTTTTAGACTCAGCAACTGATGGTGCAATCATTTTTT
CAATGGGTTCAGTTATTAAGTCGAATCAATGGCCAGTTGATAAACGTGAAGCATTTATAA
AAATTTTTAGCAAATTAAAACAGAAAATAATTTGGAAATATGAAAATGACACATTGCCTA
ATAAACCTGACAATGTTATGATCAGTTCATGGATGCCACAAAGAGACATTTTAGCTCATC
CTAATGTTAAAGTATTCATTACACATGGGGGACTGGGAGGCACAACTGAAGCTCTTGTTG
AAGGAGTTCCTATTCTAGGCTTGCCTATATTTGGTGATCAAAAAATGAATATGGTTAAAG
CAGTTACTCGAGGCTATGGTTTGCAAGTTTATTTTAAAGACATTTCTGAAGAAACTATTG
AATCTGCACTTAAAGAATTATTGAACAATCCAATGTACAAAGAAAATGCAAAAATTATTT
CAAAACGCTTTAATGATCGACCAATGACACCACAACAATCAGTAGTTTATTGGACTGAAT
ATGTTCATAGACATGACGGAGCGCCACACTTGAAAGCTGCTGCAATTGATTTGGATTTTA
TCGCATTTCACATGATTGATATTTATGCTGTTTTAATATTCATCACAATTTTAATTATTT
ATATTGATTATTTAATTCTCAAATGGCTTTTTAGAAAATGTTTTGGAAAATCAAAGAAAA
TAGATAAAAAAGATAAGAAAAATTAG
>g876.t8 Gene=g876 Length=423
MELIVIHWMGTELVEYYVNHPKVVEFLKTNEKFDICVIEVFNFDALLGIAEHVGCKVVSY
VTCGIVKWTDDISGLVSPPSYVPKHYVEYTDRMTFKQRLINTVYSHIEDFIYGQIVKKNQ
KRLYEKYFPNAIKTFDEMYKNTSILFMNTHISTSTARPYMPIQVEIGGIHIQPAKPLPKD
IQEFLDSATDGAIIFSMGSVIKSNQWPVDKREAFIKIFSKLKQKIIWKYENDTLPNKPDN
VMISSWMPQRDILAHPNVKVFITHGGLGGTTEALVEGVPILGLPIFGDQKMNMVKAVTRG
YGLQVYFKDISEETIESALKELLNNPMYKENAKIISKRFNDRPMTPQQSVVYWTEYVHRH
DGAPHLKAAAIDLDFIAFHMIDIYAVLIFITILIIYIDYLILKWLFRKCFGKSKKIDKKD
KKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g876.t8 | CDD | cd03784 | GT1_Gtf-like | 21 | 353 | 8.1883E-59 |
| 5 | g876.t8 | Gene3D | G3DSA:3.40.50.2000 | Glycogen Phosphorylase B; | 172 | 341 | 1.5E-47 |
| 2 | g876.t8 | PANTHER | PTHR48043 | EG:EG0003.4 PROTEIN-RELATED | 10 | 404 | 2.6E-117 |
| 3 | g876.t8 | PANTHER | PTHR48043:SF59 | UDP-GLUCURONOSYLTRANSFERASE | 10 | 404 | 2.6E-117 |
| 1 | g876.t8 | Pfam | PF00201 | UDP-glucoronosyl and UDP-glucosyl transferase | 23 | 415 | 1.5E-87 |
| 7 | g876.t8 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 382 | - |
| 8 | g876.t8 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 383 | 406 | - |
| 6 | g876.t8 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 407 | 423 | - |
| 11 | g876.t8 | ProSitePatterns | PS00375 | UDP-glycosyltransferases signature. | 246 | 289 | - |
| 4 | g876.t8 | SUPERFAMILY | SSF53756 | UDP-Glycosyltransferase/glycogen phosphorylase | 12 | 366 | 1.4E-94 |
| 10 | g876.t8 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 383 | 405 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008194 | UDP-glycosyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00699 (glucuronosyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
