General information for g8763.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Leucine-rich repeat-containing protein 4.
Parent gene
- The parent gene g8763 is located on chr_2: 33006344..33008707 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8763 | g8763.t1 | isoform | g8763.t1 | 33006344 | 33008707 |
| chr_2 | g8763 | g8763.t1 | exon | g8763.t1.exon1 | 33006344 | 33008707 |
| chr_2 | g8763 | g8763.t1 | cds | g8763.t1.CDS1 | 33006344 | 33008707 |
| chr_2 | g8763 | g8763.t1 | TSS | g8763.t1 | NA | NA |
| chr_2 | g8763 | g8763.t1 | TTS | g8763.t1 | NA | NA |
Sequences
>g8763.t1 Gene=g8763 Length=2364
ATGATAAGATCGCGTCTATTAGAGCAATTGTTTAAGCATACAACAGCAAATGCAGCAATA
CCGACTGTAATAGACTTACCATCAAATAAATTTAATCGACGAATGCATTGTCATAGTGGA
ATGAGCTTTTATGTTGTTATATATTTAACACTTATTGTGTTTGGTGCACTTACAAGTCAT
TATAGAGTTGAATGTCGTGAAAGTACATGTCCGACAGTGTGCACATGTAAATGGAAGGGT
GGAAAACAGACAGTCGAATGTCTCGATCGACAACTTATCAACATACCTGAGAACATTGAC
CCATCGACACAGGTGCTCGATATGAGCGGCTCAAATCTTCAAATTCTCACTGGTGAAACT
TTTAAACGTGCAGAACTGCTCAATTTGCAAAAATTGTATCTGCGCAATTGTCGTTTGGGA
CAAATTGATGATAAGGCCTTTGATGGTCTCACAAATCTCATTGAACTGGATTTATCGCAC
AATTTATTGACGTCCGTGCCTGCGGCAACCTTCCAATATATCACATCTTTACGCGATCTC
ACACTAGCTAGCAATCCAATTCAAAAAATTGAATCGAATGCATTTAATAATGTGCTGAGT
CTTACAAAACTTGATCTATCACATTGTGAATTACAAAGTATATCAGCTTCAGCATTTGAG
CGACTCGATTCGTTGCACTCGCTTAAATTGAACGGTAATAAACTTTCAGAGTTGCGTGCA
AAAACAGTTGAGACACTAAGCAAATTACATTGGGTTGAATTGCATGACAATCCATGGCTG
TGTGATTGTCGTTTACGTGCGACAAAGCTTTGGCTCACTGAAAATAATATTCCCTATCCG
ATGGCACCAATTTGCTCAGGTGGACCAGAGCGAGTCATTGATAAGTCTTTTGCTGAGCTG
CATGTTGATGATTTTGCATGTAAGCCAGAAATGTTGCCAGTAAGAAGGCATGTTGAGGCA
ATAAGTGGTGAAAATGCAACAATAATTTGTCGTACGGGTGCTGTGCCAGCAGCGCAAATT
ACATGGTATTGGAATGGAAGACTGTTAAATAATAATTCGGCATTTAGCTCATATCAAAAG
GTGCACATTTATGAAGATGGAAATTTTGAGAAACGCAGTCGTTTGGTGCTGACAAATGCT
CAAGATGCCGATTCGAGTGAATTCTATTGTGTTGCTGAAAATCGTGCTGGTAATGCAGAA
GCCAATTTTACACTTCATGTTTCCATGAGATCAGTGACAAGTGCATTTGGTAATGGACAA
ATTGCAGGACTTAGTGCAGCACTTATTATTCTTATACTCTTCATTCTACTCATCATTCTT
TTCCTTCTCGTTCGTCTTCGACGTTTGCCACAAGTCGAGACAAAAACACCGAATCAAGTT
GAAGTGATAACTAATGTAAGTCCTTCAAATAATCACAATGGTAAAGTTTGTTCTACTTCA
CCAACAAATGCAGTCAATGCCATTGACCACCGAAAAGATTCGACTGATATGAAACAGACG
AATCCAGTTCAAAAACCACCGCGTTTAACTGACATTAATTACTCTACAAGTCATTATGAT
ACAAATGGGAGTGTTGTAACAGTTGGTCCAAGTTATAGTTCACCAACTGGCAATAATCCT
GATTTAATAAATGACACAAAAAGACAAGGTAGTGGATTAGATATGACTACCATTGGTATT
GACAGTTCAACATTACTGCCATTGGCCACATCGGTAAATCTCAGTGCGGCAACAAATAAT
TTACTTGCATCACTTAGTGGGAATAGCGGACTAATTGATGCAATTGATCGACCTAGCAGT
GGTGACTATAGTCGTGCAGGTTGTGATTCACTTTATCCATCAGGCTTATGGGAAACAACA
ACACCGACTGCAGCATCAAATAATTTGTTACTTGAACAAATAAATCGATATCATCAACAT
ATGCCAATAATTGATGGCAATAGTAGCAAAATAACCACAACAACTATGAACATGGATGAT
GAGACTTCATCGGTTGATTTTTTAAATCGAACATTTCCGAAAGTATCTGCACATCATCAT
CATAATATTGATAATGACCTAAATATTGGCACATCACAACTAGCTGGCTATCCATCAGAT
TATGGTTTACCGATTGTTCCTGGCGCTGAACAATCGCAGCATCATTATAACAAATTTAAT
GCACTCACATCAACGTCATCATCGAGTAGTAGTCCCGTAGCAAATGGTGGCATGGTTCCA
ATGAATGCGAAAACGCTGCGTGTTTGGCAGAAAGGTGGTGTGCCTGTTTTGCCACCAGTG
ACAACGGCCTTAAAACGTGCATTAACCAACAGTAGAAATTCTCCCGATGAAGGTTATGTC
GGCGAAGGTGGAACTGATGTGTAG
>g8763.t1 Gene=g8763 Length=787
MIRSRLLEQLFKHTTANAAIPTVIDLPSNKFNRRMHCHSGMSFYVVIYLTLIVFGALTSH
YRVECRESTCPTVCTCKWKGGKQTVECLDRQLINIPENIDPSTQVLDMSGSNLQILTGET
FKRAELLNLQKLYLRNCRLGQIDDKAFDGLTNLIELDLSHNLLTSVPAATFQYITSLRDL
TLASNPIQKIESNAFNNVLSLTKLDLSHCELQSISASAFERLDSLHSLKLNGNKLSELRA
KTVETLSKLHWVELHDNPWLCDCRLRATKLWLTENNIPYPMAPICSGGPERVIDKSFAEL
HVDDFACKPEMLPVRRHVEAISGENATIICRTGAVPAAQITWYWNGRLLNNNSAFSSYQK
VHIYEDGNFEKRSRLVLTNAQDADSSEFYCVAENRAGNAEANFTLHVSMRSVTSAFGNGQ
IAGLSAALIILILFILLIILFLLVRLRRLPQVETKTPNQVEVITNVSPSNNHNGKVCSTS
PTNAVNAIDHRKDSTDMKQTNPVQKPPRLTDINYSTSHYDTNGSVVTVGPSYSSPTGNNP
DLINDTKRQGSGLDMTTIGIDSSTLLPLATSVNLSAATNNLLASLSGNSGLIDAIDRPSS
GDYSRAGCDSLYPSGLWETTTPTAASNNLLLEQINRYHQHMPIIDGNSSKITTTTMNMDD
ETSSVDFLNRTFPKVSAHHHHNIDNDLNIGTSQLAGYPSDYGLPIVPGAEQSQHHYNKFN
ALTSTSSSSSSPVANGGMVPMNAKTLRVWQKGGVPVLPPVTTALKRALTNSRNSPDEGYV
GEGGTDV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g8763.t1 | CDD | cd00096 | Ig | 326 | 404 | 5.80613E-11 |
| 10 | g8763.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 66 | 188 | 4.9E-31 |
| 9 | g8763.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 189 | 306 | 2.1E-27 |
| 8 | g8763.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 307 | 411 | 1.3E-17 |
| 27 | g8763.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 768 | 787 | - |
| 4 | g8763.t1 | PANTHER | PTHR24366:SF117 | IP22191P | 42 | 486 | 1.3E-97 |
| 5 | g8763.t1 | PANTHER | PTHR24366 | IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS | 42 | 486 | 1.3E-97 |
| 1 | g8763.t1 | Pfam | PF13855 | Leucine rich repeat | 128 | 187 | 2.4E-16 |
| 2 | g8763.t1 | Pfam | PF13855 | Leucine rich repeat | 200 | 257 | 1.0E-9 |
| 3 | g8763.t1 | Pfam | PF07679 | Immunoglobulin I-set domain | 314 | 407 | 4.3E-11 |
| 12 | g8763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 40 | - |
| 15 | g8763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 41 | 61 | - |
| 13 | g8763.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 62 | 420 | - |
| 14 | g8763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 421 | 444 | - |
| 11 | g8763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 445 | 787 | - |
| 32 | g8763.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 128 | 149 | 6.056 |
| 30 | g8763.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 152 | 173 | 7.858 |
| 31 | g8763.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 176 | 197 | 7.258 |
| 29 | g8763.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 200 | 221 | 7.134 |
| 28 | g8763.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 224 | 245 | 5.964 |
| 33 | g8763.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 309 | 408 | 12.604 |
| 23 | g8763.t1 | SMART | SM00369 | LRR_typ_2 | 126 | 149 | 0.82 |
| 22 | g8763.t1 | SMART | SM00369 | LRR_typ_2 | 150 | 173 | 1.4E-4 |
| 24 | g8763.t1 | SMART | SM00369 | LRR_typ_2 | 174 | 197 | 2.7 |
| 21 | g8763.t1 | SMART | SM00369 | LRR_typ_2 | 198 | 221 | 5.0 |
| 20 | g8763.t1 | SMART | SM00369 | LRR_typ_2 | 222 | 245 | 10.0 |
| 26 | g8763.t1 | SMART | SM00082 | lrrct1 | 257 | 308 | 8.3E-9 |
| 19 | g8763.t1 | SMART | SM00409 | IG_3c | 315 | 408 | 6.5E-10 |
| 25 | g8763.t1 | SMART | SM00408 | igc2_5 | 321 | 397 | 2.2E-8 |
| 6 | g8763.t1 | SUPERFAMILY | SSF52058 | L domain-like | 77 | 310 | 2.81E-42 |
| 7 | g8763.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 308 | 408 | 2.46E-17 |
| 17 | g8763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 39 | 61 | - |
| 18 | g8763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 422 | 444 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K20230 (kekkon-1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed