General information for g8802.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as DNA-binding protein D-ETS-3.
Parent gene
- The parent gene g8802 is located on chr_2: 33208567..33231308 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8802 | g8802.t2 | isoform | g8802.t2 | 33208567 | 33231308 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon1 | 33208567 | 33208793 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS1 | 33208567 | 33208793 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon2 | 33208851 | 33209140 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS2 | 33208851 | 33209140 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon3 | 33209931 | 33210014 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS3 | 33209931 | 33210014 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon4 | 33217526 | 33217630 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS4 | 33217526 | 33217630 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon5 | 33217842 | 33217892 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS5 | 33217842 | 33217892 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon6 | 33219511 | 33219588 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS6 | 33219511 | 33219588 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon7 | 33224553 | 33224600 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS7 | 33224553 | 33224600 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon8 | 33228535 | 33228724 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS8 | 33228535 | 33228724 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon9 | 33229596 | 33229640 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS9 | 33229596 | 33229640 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon10 | 33230172 | 33230183 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS10 | 33230172 | 33230183 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon11 | 33230245 | 33230393 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS11 | 33230245 | 33230393 |
| chr_2 | g8802 | g8802.t2 | exon | g8802.t2.exon12 | 33231169 | 33231308 |
| chr_2 | g8802 | g8802.t2 | cds | g8802.t2.CDS12 | 33231169 | 33231308 |
| chr_2 | g8802 | g8802.t2 | TSS | g8802.t2 | NA | NA |
| chr_2 | g8802 | g8802.t2 | TTS | g8802.t2 | NA | NA |
Sequences
>g8802.t2 Gene=g8802 Length=1419
ATGTATGAAAGTTCGTGTTCATATCAATCGGCATTAGACTTAAAAAGAACCGTGTCGCCG
TCGAATTCAATAATAAAAACAGAAGATTTTAGTTTTGGTCAGTGTAGTTCTGAATGGTCT
TCATACAGATTTCATCAATCTACATTTGAGCAATTAAAACAAAGTGTTGAAAAAGCAAAA
GCTGCATTACAAGATCGAAGTTTTTTAGGTACAAGCAGTGCTTTCAGTAGTGATTTATAT
TCATCTCCACGAATAAGTGATCATAATGAAAACATTTCTTCATCACCATTGAGTAACAAT
GTGATTCTCAGCAATACAAACAATTCTTCGAATCCACTAAATTCCAATTCCATAAATTCA
TCACCAAATGGATCAATCAATGTGTCACAAGCAAACCACAATCATTCTCAAAATGATGGA
CTGACTTCCTCACTTAGAATCAACTCAGTTTCACATATTAGTGGTCAATCAGTGAGCAAT
AATAATGAATCATCAACATCAAAGAGCAGACAACAAATTTCCGTAGTCAGCGACAAAGCA
TTAATCTCACAAAATTCCTCACCATCAAGTGACAACATAAAGTCATCAAAGTTTGCTTCA
GGAAGCATACAGAAGCATTTAGCAACAATGATTGACATTAAGAATTCTTCGACTGAATAT
TTACAACGATCATCTGGCACGTTAAATAATATTTCCATGATTTTTGAATCGTCATACAAA
ACATCATGGACAACACATTCATCACAATCATCTCAAGGTTATACAACAAACTCTTTGACA
ACAGTGAGCGTCGGAAAGACATCACTAGATTCACATTCACACTTCAGACAACCTGATCCA
TATCAAATGTTTGGTGCGACTAGCAGTAGACTAGCAAGTTCTGGTTCAGGTCAAATTCAA
TTGTGGCAATTTCTATTGGAACTGCTTAGCGACTCGACAAATGCTGGCTGTATAACTTGG
GAAGGCACAAATGGCGAGTTTAAGTTAACAGATCCCGATGAAGTAGCGAGACGTTGGGGA
GAACGAAAATCAAAGCCTAATATGAATTATGATAAACTGAGTAGAGCATTGAGATATTAT
TATGATAAAAATATAATGACCAAGGTTCATGGAAAGAGGTACGCTTACAAGTTCGATTTT
GCCGGATTAGCAGCAGCCACTCAACCGCAAGCAACAGATGCCTCATACAAATATCAAAGT
GATTTCCTTATGTCACCATATCACGGAGCAAAATTGAGCTCATTCATGTCTCCGCATCAC
AGTATGACATCATCATCTGCATCGATTTTTCCATCGTCGCTAGGTTATAGCACATATATG
GGAAGTCCTACAAATTTATATCCGCCACATTCGATGAGTAATCTCCATACTTCATCTCAT
GTGACTCCGCATCTAGGCTATGCGTCACACTACGCATGA
>g8802.t2 Gene=g8802 Length=472
MYESSCSYQSALDLKRTVSPSNSIIKTEDFSFGQCSSEWSSYRFHQSTFEQLKQSVEKAK
AALQDRSFLGTSSAFSSDLYSSPRISDHNENISSSPLSNNVILSNTNNSSNPLNSNSINS
SPNGSINVSQANHNHSQNDGLTSSLRINSVSHISGQSVSNNNESSTSKSRQQISVVSDKA
LISQNSSPSSDNIKSSKFASGSIQKHLATMIDIKNSSTEYLQRSSGTLNNISMIFESSYK
TSWTTHSSQSSQGYTTNSLTTVSVGKTSLDSHSHFRQPDPYQMFGATSSRLASSGSGQIQ
LWQFLLELLSDSTNAGCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYY
YDKNIMTKVHGKRYAYKFDFAGLAAATQPQATDASYKYQSDFLMSPYHGAKLSSFMSPHH
SMTSSSASIFPSSLGYSTYMGSPTNLYPPHSMSNLHTSSHVTPHLGYASHYA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g8802.t2 | Gene3D | G3DSA:1.10.10.10 | winged helix repressor DNA binding domain | 263 | 395 | 1.9E-48 |
| 13 | g8802.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 153 | 173 | - |
| 2 | g8802.t2 | PANTHER | PTHR11849 | ETS | 228 | 466 | 1.2E-92 |
| 3 | g8802.t2 | PANTHER | PTHR11849:SF161 | FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR | 228 | 466 | 1.2E-92 |
| 5 | g8802.t2 | PRINTS | PR00454 | ETS domain signature | 299 | 312 | 8.7E-31 |
| 4 | g8802.t2 | PRINTS | PR00454 | ETS domain signature | 323 | 341 | 8.7E-31 |
| 6 | g8802.t2 | PRINTS | PR00454 | ETS domain signature | 342 | 360 | 8.7E-31 |
| 7 | g8802.t2 | PRINTS | PR00454 | ETS domain signature | 361 | 379 | 8.7E-31 |
| 1 | g8802.t2 | Pfam | PF00178 | Ets-domain | 300 | 378 | 2.2E-34 |
| 10 | g8802.t2 | ProSitePatterns | PS00345 | Ets-domain signature 1. | 301 | 309 | - |
| 11 | g8802.t2 | ProSitePatterns | PS00346 | Ets-domain signature 2. | 345 | 360 | - |
| 14 | g8802.t2 | ProSiteProfiles | PS50061 | Ets-domain profile. | 299 | 379 | 48.245 |
| 12 | g8802.t2 | SMART | SM00413 | etsneu2 | 298 | 383 | 5.0E-57 |
| 8 | g8802.t2 | SUPERFAMILY | SSF46785 | Winged helix DNA-binding domain | 296 | 440 | 2.2E-49 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | BP |
| GO:0043565 | sequence-specific DNA binding | MF |
| GO:0003700 | DNA-binding transcription factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K09436 (friend leukemia integration 1 transcription factor)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed