General information for g8819.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose transporter type 1.
Parent gene
- The parent gene g8819 is located on chr_2: 33340461..33350380 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8819 | g8819.t1 | isoform | g8819.t1 | 33337165 | 33349347 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon1 | 33337165 | 33337454 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS1 | 33337165 | 33337454 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon2 | 33338740 | 33338831 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS2 | 33338740 | 33338831 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon3 | 33340319 | 33340345 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS3 | 33340319 | 33340345 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon4 | 33340461 | 33340600 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS4 | 33340461 | 33340600 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon5 | 33340659 | 33340862 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS5 | 33340659 | 33340862 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon6 | 33343398 | 33343520 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS6 | 33343398 | 33343520 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon7 | 33343610 | 33343699 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS7 | 33343610 | 33343699 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon8 | 33343876 | 33344063 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS8 | 33343876 | 33344063 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon9 | 33344137 | 33344415 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS9 | 33344137 | 33344415 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon10 | 33344485 | 33344609 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS10 | 33344485 | 33344609 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon11 | 33345003 | 33345259 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS11 | 33345003 | 33345259 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon12 | 33345667 | 33345804 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS12 | 33345667 | 33345804 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon13 | 33345926 | 33346064 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS13 | 33345926 | 33346064 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon14 | 33348758 | 33348959 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS14 | 33348758 | 33348959 |
| chr_2 | g8819 | g8819.t1 | exon | g8819.t1.exon15 | 33349164 | 33349347 |
| chr_2 | g8819 | g8819.t1 | cds | g8819.t1.CDS15 | 33349164 | 33349347 |
| chr_2 | g8819 | g8819.t1 | TSS | g8819.t1 | NA | NA |
| chr_2 | g8819 | g8819.t1 | TTS | g8819.t1 | NA | NA |
Sequences
>g8819.t1 Gene=g8819 Length=2478
ATGAATGTACATGAAATTAATGTTTATATTGCTGCTGTTATTTTAGTCGTGTCGGGTTTA
AACGAGGAATCAACGTATGATTATGTTTTTGGAGGTCCTAGGTTGCCTCATCGGTCGGCT
GTTTCACACTCTACACTCAAGCTGACGTCACCACCGACAAGGTTGCGTCCCGAAAGTAGA
CTTTATACGCAACGAAAATTTGGTGGAAGTTTAGACGATGGAAGAACATCATCATCACAC
TCGCATTTTCATTATCAGACACCGCGACGTTCGCCGGGAAATTCATTGAAACGTAAAAGA
AGTTTAATTGATGGTAGATGTTCTCGAGCGTCATTTAAGAGTAATGTTGATGACGAAGAA
ACTACATTACGACAGCTACTTAATGATATGAATTTAAATTGTAAATTGGACAATTTACAA
AGAGGAGATCAATATATGGAGACATCAGTAGCATTGTGCGAGATTCGCACTCAACTCCAA
GAGCTGACAAAGTCAGTTGAGAGTTGTCAAAGTGAAGTACACGAAGTCAAAAGGGATATG
GTTGCGATAAAACATGAATTGGACACAGTTCAACAAGTAAAAGAAGAAATCGAAGAGCTT
CGTGAATACGTTGACCGCTTAGAAGAGCACACACAAAGAAGGAAACTTCGTCTACTGGAA
CAAGGTTTAACTTTCTTCCTTACATACTCTATATTCGCTGCCGTTTTGGGCATGCTTCAA
TTCGGTTACAATACCGGAGTGATAAATGCGCCAGAAATTAATATAGAAAACTTTATGAAA
GACGTTTATAAGGATCGTTATGGCGAAGATATAAGCGAAGAATTTATTCAACAATTGTAT
TCTGTGGCTGTGTCGATTTTTGCAATCGGTGGTATGCTCGGTGGCTTTTGCGGTGGTTGG
ATAGCAAATCGTTTTGGACGAAAGGGAGGCCTATTATTGAATAATGTTCTCGGTATATCT
GGTGCATGTTTGATGGGCTTCACAAAGTTTCTCAATTCATACGAAGTGCTATTCCTGGGA
CGATTTATTATTGGAGTTAATTGTGGTTTAAATACATCACTAGTTCCAATGTATATATCT
GAAATTGCGCCATTAAATTTACGTGGTGGTTTAGGTACTGTTAATCAATTGGCTGTGACC
ATAGGTTTACTTCTCTCACAAGTGCTCGGCATTGAGCAAATATTAGGAACAAACGACGGA
TGGCCAGTATTATTAGGTTTAGCGGTGTGTCCAGCTATTCTACAATTAATTTTATTACCG
ATTTGTCCCGAATCGCCGCGTTATTTATTGATTACAAAACAATGGGAGGAAGAAGCAAGA
AAAGCTTTAAGAAGACTCCGAGCATCAAGTCAAGTAGAAGAAGATATTGAGGAAATGCGA
GCGGAAGAGCGTGCACAGCAATCAGAGAGCAGTATTTCAATTATGGAATTAATCTGTTCG
CCAACCCTACGAGCACCTCTCATAATTGGAATTGTAATGCAATTGAGTCAACAGTTGAGT
GGTATCAATGCTGTATTTTATTATTCCACTTCACTCTTCATGAGTTCCGGTCTTACTGAA
GAGAATGCAAAGTTTGCAACAATAGGAATTGGCTGCATCATGGTTTTGATGACATTGGTG
TCTATACCATTAATGGATAAAACAGGACGTCGCACTTTACATTTATACGGTCTTGGAGGG
ATGTTTATTTTCTCAATATTCATTACCATTTCATTCCTAATAAAGGAAATGATCGACTGG
ATGTCCTATCTTTCGGTGGTTTCAACATTGGCGTTTGTTGTATTTTTCGCTGTTGGTCCG
GGTTCCATTCCTTGGATGATTACGGCCGAATTATTTTCACAAGGTCCACGACCAACAGCA
ATGGCCATAGCAGTTTTAGTCAATTGGCTAGCGAACTTTGTAGTTGGCATTGGTTTTCCT
AGCTTAAAGGCTGCACTGGATAACTACACATTCTTGCCGTTTAGCGTATTCCTAGCAATA
TTTTGGATATTTACATATAAGAAGGTGCCCGAGACAAAAAATAAGACATTTGAAGAAATT
CTTGCACTATTTCGTCATGGAAATGGAAGATCCCTTCGTGATAGTAGACTTTACGGGAGT
ATGCTAAACTGCGTGAATAATTTGAATTTGGAACCGCAAAGCGGAATTGAACGGACGGCT
CTGGTATCCGAGGAAAAACAGGATTCACAAACGCGTGAATTAATGGAAGAGGTTTTCCCA
TTGACTGACCAAGTCAATTTATTGAGTGAAACATCTCGCTATGCATTAGATAACTTACTT
GCATCACACTTAATCGAATATGGTACGAAATCAAATGCAAAAATTTCTAATAATAGTAAC
ATTAATAACACTAATAATACATGTAATAATGTAACATGTTCACCATTGCTATCTAAAAAG
CGCCAACAAAGCCAACAAAGCTTTAGTAGGCGGCAAACTGCTCAAGGAATGGAACACTCA
GGTATATCTAAAATTTAA
>g8819.t1 Gene=g8819 Length=825
MNVHEINVYIAAVILVVSGLNEESTYDYVFGGPRLPHRSAVSHSTLKLTSPPTRLRPESR
LYTQRKFGGSLDDGRTSSSHSHFHYQTPRRSPGNSLKRKRSLIDGRCSRASFKSNVDDEE
TTLRQLLNDMNLNCKLDNLQRGDQYMETSVALCEIRTQLQELTKSVESCQSEVHEVKRDM
VAIKHELDTVQQVKEEIEELREYVDRLEEHTQRRKLRLLEQGLTFFLTYSIFAAVLGMLQ
FGYNTGVINAPEINIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGGFCGGW
IANRFGRKGGLLLNNVLGISGACLMGFTKFLNSYEVLFLGRFIIGVNCGLNTSLVPMYIS
EIAPLNLRGGLGTVNQLAVTIGLLLSQVLGIEQILGTNDGWPVLLGLAVCPAILQLILLP
ICPESPRYLLITKQWEEEARKALRRLRASSQVEEDIEEMRAEERAQQSESSISIMELICS
PTLRAPLIIGIVMQLSQQLSGINAVFYYSTSLFMSSGLTEENAKFATIGIGCIMVLMTLV
SIPLMDKTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVSTLAFVVFFAVGP
GSIPWMITAELFSQGPRPTAMAIAVLVNWLANFVVGIGFPSLKAALDNYTFLPFSVFLAI
FWIFTYKKVPETKNKTFEEILALFRHGNGRSLRDSRLYGSMLNCVNNLNLEPQSGIERTA
LVSEEKQDSQTRELMEEVFPLTDQVNLLSETSRYALDNLLASHLIEYGTKSNAKISNNSN
INNTNNTCNNVTCSPLLSKKRQQSQQSFSRRQTAQGMEHSGISKI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 38 | g8819.t1 | CDD | cd17431 | MFS_GLUT_Class1 | 229 | 675 | 0.0 |
| 12 | g8819.t1 | Coils | Coil | Coil | 159 | 213 | - |
| 11 | g8819.t1 | Coils | Coil | Coil | 449 | 469 | - |
| 10 | g8819.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 185 | 688 | 4.9E-148 |
| 52 | g8819.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 68 | 100 | - |
| 53 | g8819.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 70 | 92 | - |
| 51 | g8819.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 799 | 825 | - |
| 2 | g8819.t1 | PANTHER | PTHR23503:SF8 | SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 | 223 | 692 | 1.4E-245 |
| 3 | g8819.t1 | PANTHER | PTHR23503 | - | 223 | 692 | 1.4E-245 |
| 6 | g8819.t1 | PRINTS | PR00171 | Sugar transporter signature | 238 | 248 | 5.4E-24 |
| 7 | g8819.t1 | PRINTS | PR00171 | Sugar transporter signature | 338 | 357 | 5.4E-24 |
| 8 | g8819.t1 | PRINTS | PR00171 | Sugar transporter signature | 497 | 507 | 5.4E-24 |
| 4 | g8819.t1 | PRINTS | PR00171 | Sugar transporter signature | 586 | 607 | 5.4E-24 |
| 5 | g8819.t1 | PRINTS | PR00171 | Sugar transporter signature | 609 | 621 | 5.4E-24 |
| 1 | g8819.t1 | Pfam | PF00083 | Sugar (and other) transporter | 232 | 684 | 3.9E-134 |
| 13 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 222 | - |
| 31 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 223 | 243 | - |
| 24 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 244 | 278 | - |
| 33 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 279 | 302 | - |
| 19 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 303 | 310 | - |
| 28 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 311 | 331 | - |
| 22 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 332 | 336 | - |
| 30 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 337 | 359 | - |
| 15 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 360 | 370 | - |
| 36 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 371 | 389 | - |
| 25 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 390 | 400 | - |
| 37 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 401 | 421 | - |
| 14 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 422 | 484 | - |
| 34 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 485 | 508 | - |
| 23 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 509 | 527 | - |
| 32 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 528 | 546 | - |
| 18 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 547 | 552 | - |
| 27 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 553 | 574 | - |
| 21 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 575 | 579 | - |
| 29 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 580 | 599 | - |
| 17 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 600 | 619 | - |
| 35 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 620 | 642 | - |
| 20 | g8819.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 643 | 647 | - |
| 26 | g8819.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 648 | 666 | - |
| 16 | g8819.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 667 | 825 | - |
| 50 | g8819.t1 | ProSitePatterns | PS00217 | Sugar transport proteins signature 2. | 343 | 368 | - |
| 55 | g8819.t1 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 230 | 673 | 42.514 |
| 9 | g8819.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 228 | 679 | 9.81E-56 |
| 54 | g8819.t1 | TIGRFAM | TIGR00879 | SP: MFS transporter, sugar porter (SP) family | 209 | 680 | 2.2E-120 |
| 44 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 222 | 244 | - |
| 46 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 280 | 302 | - |
| 41 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 309 | 328 | - |
| 40 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 338 | 360 | - |
| 48 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 369 | 391 | - |
| 47 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 401 | 423 | - |
| 49 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 525 | 542 | - |
| 39 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 552 | 574 | - |
| 42 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 583 | 605 | - |
| 43 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 620 | 642 | - |
| 45 | g8819.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 649 | 666 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K07299 (MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
