General information for g8876.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.
Parent gene
- The parent gene g8876 is located on chr_2: 33616160..33618428 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8876 | g8876.t1 | TTS | g8876.t1 | 33614267 | 33614267 |
| chr_2 | g8876 | g8876.t1 | isoform | g8876.t1 | 33615503 | 33618428 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon1 | 33615503 | 33615537 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS1 | 33615503 | 33615537 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon2 | 33616004 | 33616092 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS2 | 33616004 | 33616092 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon3 | 33616158 | 33616362 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS3 | 33616158 | 33616362 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon4 | 33616428 | 33616439 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS4 | 33616428 | 33616439 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon5 | 33617074 | 33617205 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS5 | 33617074 | 33617205 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon6 | 33617582 | 33617643 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS6 | 33617582 | 33617643 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon7 | 33617772 | 33617817 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS7 | 33617772 | 33617817 |
| chr_2 | g8876 | g8876.t1 | TSS | g8876.t1 | 33617877 | 33617877 |
| chr_2 | g8876 | g8876.t1 | exon | g8876.t1.exon8 | 33618416 | 33618428 |
| chr_2 | g8876 | g8876.t1 | cds | g8876.t1.CDS8 | 33618416 | 33618428 |
Sequences
>g8876.t1 Gene=g8876 Length=594
ATGGCTAAATTGGAGTTTTTAAATAGCTTTCGATCGACAAATTATAGTTCACGACCGATA
TCAAACATGTCGGATATTGATATTCTGAATATTGACAACATAATAGCGAGACTTTTGGAA
GTTCGAGGCTCACGACCAGGGAAAAATGTTCAGCTCACTGAATCAGAAATACGTGGATTA
TGTTTAAAATCACGAGAGATTTTCCTATCACAACCAATTTTACTTGAATTGGAAGCCCCA
CTTAAGATTTGTGGTGATATCCATGGTCAGTACTACGATCTTTTGCGTCTGTTCGAGTAT
GGAGGATTTCCACCAGAATCCAATTATCTATTTCTTGGCGATTATGTTGATCGTGGAAAA
CAGAGTCTTGAAACTATCTGTCTTTTGTTGGCGTACAAAATTAAATATCCTGAAAATTTC
TTTTTATTACGTGGAAATCATGAGTGTGCAAGTATTAATCGAATTTACGGATTCTACGAT
GAATGCAAACGACGTTACAATATAAAATTGTGGAAGACTTTTACTGACTGCTTCAATTGC
TTACCTGTAGCTGCTATCGTCGATGAGAAAATTTTCTGCTGTCATGGAGGATAA
>g8876.t1 Gene=g8876 Length=197
MAKLEFLNSFRSTNYSSRPISNMSDIDILNIDNIIARLLEVRGSRPGKNVQLTESEIRGL
CLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGK
QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNC
LPVAAIVDEKIFCCHGG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g8876.t1 | Gene3D | G3DSA:3.60.21.10 | - | 23 | 197 | 4.4E-78 |
| 3 | g8876.t1 | PANTHER | PTHR11668:SF460 | SERINE/THREONINE-PROTEIN PHOSPHATASE | 27 | 197 | 1.8E-117 |
| 4 | g8876.t1 | PANTHER | PTHR11668 | SERINE/THREONINE PROTEIN PHOSPHATASE | 27 | 197 | 1.8E-117 |
| 6 | g8876.t1 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 80 | 107 | 3.8E-57 |
| 5 | g8876.t1 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 109 | 136 | 3.8E-57 |
| 8 | g8876.t1 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 142 | 166 | 3.8E-57 |
| 7 | g8876.t1 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 176 | 197 | 3.8E-57 |
| 1 | g8876.t1 | Pfam | PF16891 | Serine-threonine protein phosphatase N-terminal domain | 31 | 78 | 2.7E-23 |
| 2 | g8876.t1 | Pfam | PF00149 | Calcineurin-like phosphoesterase | 82 | 197 | 3.7E-27 |
| 11 | g8876.t1 | ProSitePatterns | PS00125 | Serine/threonine specific protein phosphatases signature. | 143 | 148 | - |
| 10 | g8876.t1 | SMART | SM00156 | pp2a_7 | 52 | 197 | 9.5E-29 |
| 9 | g8876.t1 | SUPERFAMILY | SSF56300 | Metallo-dependent phosphatases | 37 | 197 | 3.65E-67 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
