General information for g8942.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Importin subunit alpha-7.
Parent gene
- The parent gene g8942 is located on chr_2: 34006200..34007466 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8942 | g8942.t6 | isoform | g8942.t6 | 34006200 | 34006703 |
| chr_2 | g8942 | g8942.t6 | exon | g8942.t6.exon1 | 34006200 | 34006223 |
| chr_2 | g8942 | g8942.t6 | cds | g8942.t6.CDS1 | 34006200 | 34006223 |
| chr_2 | g8942 | g8942.t6 | exon | g8942.t6.exon2 | 34006278 | 34006703 |
| chr_2 | g8942 | g8942.t6 | cds | g8942.t6.CDS2 | 34006278 | 34006703 |
| chr_2 | g8942 | g8942.t6 | TSS | g8942.t6 | 34007075 | 34007075 |
| chr_2 | g8942 | g8942.t6 | TTS | g8942.t6 | NA | NA |
Sequences
>g8942.t6 Gene=g8942 Length=450
ATGAACAGTTCAAGAAATGCTGCTCGCTATAAAAACCAAGGTCTTGATCAGGCTGAGCTT
AGACGACGACGAGAAGAGGAAGGAATTCAGTTGAGAAAACAAAAACGTGAACAACAATTA
ACAAAACGAAGAAACCTTAATCCACAAATTGATGATCAAGATGATGATGACAATTCTGAA
ATGCTCACTGATCGCCCTATAGAAATGCAAGAAATTCCATCTCAACAGTCAGCAAACACA
GTGATTCGTTTCGAGACGGTCCAAGCATTATATAGTTCGAATGTCGCTGATCAACTTGCT
GCCACACAAAAATTCAGAAAACTTTTGAGCAAAGAACCAAATCCTCCTATTGATGAAGTA
ATAAAAACAGGGATTGTTGGTCGCTTTGTCGAGCTTTTAAATAATCATGAAAATACAACT
CTTCAATTTGAAGCAGCATGGGCTTTAACA
>g8942.t6 Gene=g8942 Length=150
MNSSRNAARYKNQGLDQAELRRRREEEGIQLRKQKREQQLTKRRNLNPQIDDQDDDDNSE
MLTDRPIEMQEIPSQQSANTVIRFETVQALYSSNVADQLAATQKFRKLLSKEPNPPIDEV
IKTGIVGRFVELLNNHENTTLQFEAAWALT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g8942.t6 | Coils | Coil | Coil | 17 | 37 | - |
| 9 | g8942.t6 | Gene3D | G3DSA:1.20.5.690 | Single helix bin | 5 | 46 | 2.9E-15 |
| 8 | g8942.t6 | Gene3D | G3DSA:1.25.10.10 | - | 81 | 150 | 9.7E-23 |
| 6 | g8942.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 65 | - |
| 7 | g8942.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 15 | 51 | - |
| 3 | g8942.t6 | PANTHER | PTHR23316 | IMPORTIN ALPHA | 8 | 150 | 8.3E-42 |
| 4 | g8942.t6 | PANTHER | PTHR23316:SF8 | IMPORTIN SUBUNIT ALPHA-7 | 8 | 150 | 8.3E-42 |
| 1 | g8942.t6 | Pfam | PF01749 | Importin beta binding domain | 8 | 103 | 1.4E-22 |
| 2 | g8942.t6 | Pfam | PF00514 | Armadillo/beta-catenin-like repeat | 114 | 150 | 9.1E-9 |
| 11 | g8942.t6 | ProSiteProfiles | PS51214 | IBB domain profile. | 1 | 53 | 14.038 |
| 5 | g8942.t6 | SUPERFAMILY | SSF48371 | ARM repeat | 2 | 150 | 1.04E-23 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0061608 | nuclear import signal receptor activity | MF |
| GO:0006606 | protein import into nucleus | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
