Gene loci information

Transcript annotation

  • This transcript has been annotated as Arginine kinase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8960 g8960.t14 TSS g8960.t14 34205498 34205498
chr_2 g8960 g8960.t14 isoform g8960.t14 34205523 34214613
chr_2 g8960 g8960.t14 exon g8960.t14.exon1 34205523 34205566
chr_2 g8960 g8960.t14 cds g8960.t14.CDS1 34205523 34205566
chr_2 g8960 g8960.t14 exon g8960.t14.exon2 34213006 34213280
chr_2 g8960 g8960.t14 cds g8960.t14.CDS2 34213006 34213280
chr_2 g8960 g8960.t14 exon g8960.t14.exon3 34213336 34213874
chr_2 g8960 g8960.t14 cds g8960.t14.CDS3 34213336 34213874
chr_2 g8960 g8960.t14 exon g8960.t14.exon4 34213936 34214157
chr_2 g8960 g8960.t14 cds g8960.t14.CDS4 34213936 34214157
chr_2 g8960 g8960.t14 exon g8960.t14.exon5 34214230 34214613
chr_2 g8960 g8960.t14 cds g8960.t14.CDS5 34214230 34214277
chr_2 g8960 g8960.t14 TTS g8960.t14 34214625 34214625

Sequences

>g8960.t14 Gene=g8960 Length=1464
ATGTTTGGTCTTTGGTATCTTTCACTCGCAGTTAAAGAGATTTGTAACAAATCCGAAATG
GTTGACGCTGCAGTACTTGAGAAATTGGAATCAGGCTTTGCCAAGCTCCAAGCCTCTGAC
TCGAAATCATTGCTTAAAAAGTATTTGACCAAGGAAGTCTTTGATAATCTTAAGAACAAG
AAGACCCCAACATTTGGTTCAACTTTGCTTGATGTCATCCAATCTGGTTTAGAAAACCAC
GACTCTGGCGTCGGAATTTACGCACCAGATGCCGAGGCTTACACAACTTTCGCTGAATTG
TTTGACCCAATCATTGAAGACTACCATGGTGGATTCAAGAAGACCGACAAGCATCCAGCA
AAGGACTTTGGTGATGTAAATGCATTTGGAGATTTGGATCCAACTGGTGAATTCGTTGTC
TCAACTCGTGTCCGTTGCGGTCGCTCAATGGAAGGATATCCATTCAATCCATGCTTGACT
GAAGCACAATACAAAGAAATGGAACAAAAGGTTTCAACCACATTGTCAGGCTTGGAAGGT
GAATTGAAGGGCAAATTCTACCCATTGACTGGCATGGACAAAGCTACTCAACAACAACTC
ATCGATGACCATTTCTTGTTCAAAGAAGGTGATCGCTTCTTGCAAGCTGCCAATGCTTGC
CGCTATTGGCCATCAGGTCGCGGTATCTACCACAATGATGCCAAGACTTTCCTTGTCTGG
TGCAATGAAGAAGATCACTTGCGTATCATTTCAATGCAAATGGGTGGCAATCTTGGTGAA
GTTTTCCGTCGTTTGACAACTGCCGTTAATGACATTGAGAAGCGTATTCCATTCAGCCAC
AACGACCGCTTGGGATTCCTCACATTCTGCCCAACCAACTTGGGAACAACCATCCGTGCA
TCAGTTCACATTAAGGTTCCAAAATTGGCTGCCAACAAAGCTCGTCTTGAGGAAGTTGCT
TCCAAATACAATTTGCAAGTTCGTGGCACACGCGGAGAACATACAGAGGCTGAAGGTGGC
ATTTATGATATTTCAAACAAGAGACGTATGGGCTTGACTGAATTCCAAGCTGTCAAGGAG
ATGTACGATGGAATTACTGAAATCATCAAGATTGAAAAGTCATTGTAAAGTGTGTAAAAG
CAAAAACAAAACAACCCAACTTAAAATTGTCATCTATTTTCAAAATTATACATTAATATA
AAAAACACATATACACACATGAATTAACAACAAAACTCAATCGTCATTTGCAATGGCGAT
CAAAGATTTGGAAATCTTTCATCAGTGATCTTTATTCTTGTTTAATTTAATTGATAAAAA
AATGTGTCCTATTCTCTCCATCTCAGTATAAGTTTGATGTGATTGATCACAAGCATTAAG
AATATTTTGGAATAAAATGTGAATTTAACATCTATTACCACATACAGCACATGCAAACAA
GAAGTTAATTAAATAAAAACCGTA

>g8960.t14 Gene=g8960 Length=375
MFGLWYLSLAVKEICNKSEMVDAAVLEKLESGFAKLQASDSKSLLKKYLTKEVFDNLKNK
KTPTFGSTLLDVIQSGLENHDSGVGIYAPDAEAYTTFAELFDPIIEDYHGGFKKTDKHPA
KDFGDVNAFGDLDPTGEFVVSTRVRCGRSMEGYPFNPCLTEAQYKEMEQKVSTTLSGLEG
ELKGKFYPLTGMDKATQQQLIDDHFLFKEGDRFLQAANACRYWPSGRGIYHNDAKTFLVW
CNEEDHLRIISMQMGGNLGEVFRRLTTAVNDIEKRIPFSHNDRLGFLTFCPTNLGTTIRA
SVHIKVPKLAANKARLEEVASKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKE
MYDGITEIIKIEKSL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g8960.t14 CDD cd07932 arginine_kinase_like 28 375 0.0
9 g8960.t14 Gene3D G3DSA:1.10.135.10 Transferase Creatine Kinase 20 114 3.0E-38
8 g8960.t14 Gene3D G3DSA:3.30.590.10 Glutamine synthetase/guanido kinase 117 375 3.4E-120
3 g8960.t14 PANTHER PTHR11547:SF38 ARGININE KINASE-RELATED 25 374 5.2E-154
4 g8960.t14 PANTHER PTHR11547 ARGININE OR CREATINE KINASE 25 374 5.2E-154
1 g8960.t14 Pfam PF02807 ATP:guanido phosphotransferase, N-terminal domain 39 106 7.7E-30
2 g8960.t14 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 166 374 2.5E-86
7 g8960.t14 ProSitePatterns PS00112 Phosphagen kinase active site signature. 290 296 -
11 g8960.t14 ProSiteProfiles PS51509 Phosphagen kinase N-terminal domain profile. 25 110 26.463
10 g8960.t14 ProSiteProfiles PS51510 Phosphagen kinase C-terminal domain profile. 138 375 88.499
5 g8960.t14 SUPERFAMILY SSF48034 Guanido kinase N-terminal domain 37 119 3.4E-33
6 g8960.t14 SUPERFAMILY SSF55931 Glutamine synthetase/guanido kinase 116 374 6.17E-105

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0046314 phosphocreatine biosynthetic process BP
GO:0016301 kinase activity MF
GO:0004111 creatine kinase activity MF
GO:0003824 catalytic activity MF
GO:0016772 transferase activity, transferring phosphorus-containing groups MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values