General information for g9117.t63
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Trifunctional enzyme subunit alpha, mitochondrial.
Parent gene
- The parent gene g9117 is located on chr_1: 221472..222354 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9117 | g9117.t63 | isoform | g9117.t63 | 219159 | 220550 |
| chr_1 | g9117 | g9117.t63 | exon | g9117.t63.exon1 | 219159 | 219343 |
| chr_1 | g9117 | g9117.t63 | exon | g9117.t63.exon2 | 219397 | 219629 |
| chr_1 | g9117 | g9117.t63 | cds | g9117.t63.CDS1 | 219610 | 219629 |
| chr_1 | g9117 | g9117.t63 | exon | g9117.t63.exon3 | 219766 | 220005 |
| chr_1 | g9117 | g9117.t63 | cds | g9117.t63.CDS2 | 219766 | 220005 |
| chr_1 | g9117 | g9117.t63 | exon | g9117.t63.exon4 | 220059 | 220202 |
| chr_1 | g9117 | g9117.t63 | cds | g9117.t63.CDS3 | 220059 | 220202 |
| chr_1 | g9117 | g9117.t63 | exon | g9117.t63.exon5 | 220262 | 220550 |
| chr_1 | g9117 | g9117.t63 | cds | g9117.t63.CDS4 | 220262 | 220472 |
| chr_1 | g9117 | g9117.t63 | TSS | g9117.t63 | NA | NA |
| chr_1 | g9117 | g9117.t63 | TTS | g9117.t63 | NA | NA |
Sequences
>g9117.t63 Gene=g9117 Length=1091
GGTATTGGACAAATACAAAAAGGTCTTGATGGTGCAGTAAAAAGAAAAAAAATTAGCAGT
TTGGATAAAGATAAAATAATGAGTAATTTAACATCGACATTGTCCTACGAACCTTTCAGA
AATGCAGATATAGTTATCGAAGCTGTTTTTGAGAATTTAGACATTAAACATCGTGTAATA
AAGGAAATGGAATCTGTCATTCCTGAACATTGCATTATTGCAACAAATACATCAGCTCTT
CCCATCACAAAAATTGCAGCCGGTTCATCAAGACCAGATAAAGTTATTGGCATGCACTAT
TTTTCACCAGTTGATAAGATGCAACTTTTGGAAATTATCACACATCCGGGCACATCTTTA
GAAGCAAAACAAGCAGCAGTTGATTTAGGACTGAAGCAAGGAAAAGTAGTTATTACAGTT
GGTGATGGACCAGGTTTTTATACAACTCGAATTCTTTCAACTATGGTTGCTGAGGGCATG
TTGATAATGCAAGAAGGTGTCGATCCAAAGGACATTGATAAACTCACAAAACAATTTGGT
TTCCCAGTTGGTCTTGCTACTTTAATTGATGAAGTGGGAATTGATGTTGGTATGCACATT
TTCAAAGACTTGCAAGCAGCTTTTGGTGATCGTTTATCAGGCGGTGACGCAAATATCTCA
GTAGATTTGGTTAATGTTTATCATAAAACTTAGGAAAAGGAATTTTCGTTTATGATGGTC
AAACGAAAGGAAGTCGTGAAGTCAATCCTGAGGCATTAGCAATCATTAAACAAAAATACG
CTTTGGTGTCCAAAGGAGCAAATCAACCAGAAGATTTACAATTGAGAATGGTGTCTAGAT
TTATTAATGAAGCCGTAATGTGTCTTGAAGAAAAGATTTTGCACAGTCCATTAGAAGGTG
ATATTGGTGCCGTATTTGGTCTCGGATTCCCACCTTTTTCCGGTGGTCCATTTAAATTTG
TTGATACATTCGGAGCTGATAAGCTTGTAAACAAAATGCTATCATATGCAGAGCTCTATG
GAAGACCGTTTCAACCAGCTCAAACATTACTTGATATGGCAAAAGATTCATCAAAGAAAT
TTTATAAATAA
>g9117.t63 Gene=g9117 Length=204
MSNLTSTLSYEPFRNADIVIEAVFENLDIKHRVIKEMESVIPEHCIIATNTSALPITKIA
AGSSRPDKVIGMHYFSPVDKMQLLEIITHPGTSLEAKQAAVDLGLKQGKVVITVGDGPGF
YTTRILSTMVAEGMLIMQEGVDPKDIDKLTKQFGFPVGLATLIDEVGIDVGMHIFKDLQA
AFGDRLSGGDANISVDLVNVYHKT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g9117.t63 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 117 | 0 |
| 7 | g9117.t63 | Gene3D | G3DSA:1.10.1040.50 | - | 120 | 202 | 0 |
| 3 | g9117.t63 | PANTHER | PTHR43612 | TRIFUNCTIONAL ENZYME SUBUNIT ALPHA | 1 | 198 | 0 |
| 2 | g9117.t63 | Pfam | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | 1 | 116 | 0 |
| 1 | g9117.t63 | Pfam | PF00725 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | 119 | 193 | 0 |
| 4 | g9117.t63 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 2 | 118 | 0 |
| 5 | g9117.t63 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 118 | 184 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0070403 | NAD+ binding | MF |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
