General information for g9117.t64
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Trifunctional enzyme subunit alpha, mitochondrial.
Parent gene
- The parent gene g9117 is located on chr_1: 221472..222354 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9117 | g9117.t64 | isoform | g9117.t64 | 219159 | 220696 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon1 | 219159 | 219343 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon2 | 219397 | 219609 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon3 | 219674 | 219704 |
| chr_1 | g9117 | g9117.t64 | cds | g9117.t64.CDS1 | 219700 | 219704 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon4 | 219766 | 220005 |
| chr_1 | g9117 | g9117.t64 | cds | g9117.t64.CDS2 | 219766 | 220005 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon5 | 220059 | 220202 |
| chr_1 | g9117 | g9117.t64 | cds | g9117.t64.CDS3 | 220059 | 220202 |
| chr_1 | g9117 | g9117.t64 | exon | g9117.t64.exon6 | 220262 | 220696 |
| chr_1 | g9117 | g9117.t64 | cds | g9117.t64.CDS4 | 220262 | 220634 |
| chr_1 | g9117 | g9117.t64 | TSS | g9117.t64 | NA | NA |
| chr_1 | g9117 | g9117.t64 | TTS | g9117.t64 | NA | NA |
Sequences
>g9117.t64 Gene=g9117 Length=1248
AAAATCGTTTTGGAAATCCCAGTCGACCTGTAAAAAATGTTGCTGTATTGGGCGCTGGAT
TGATGGGGGCTGGTATTGTTCAAGTAACAGTTGATAAAGGCTATAATGTCATAATGAAAG
ATGCAACAGAGGCTGGTTTATCAAGAGGTATTGGACAAATACAAAAAGGTCTTGATGGTG
CAGTAAAAAGAAAAAAAATTAGCAGTTTGGATAAAGATAAAATAATGAGTAATTTAACAT
CGACATTGTCCTACGAACCTTTCAGAAATGCAGATATAGTTATCGAAGCTGTTTTTGAGA
ATTTAGACATTAAACATCGTGTAATAAAGGAAATGGAATCTGTCATTCCTGAACATTGCA
TTATTGCAACAAATACATCAGCTCTTCCCATCACAAAAATTGCAGCCGGTTCATCAAGAC
CAGATAAAGTTATTGGCATGCACTATTTTTCACCAGTTGATAAGATGCAACTTTTGGAAA
TTATCACACATCCGGGCACATCTTTAGAAGCAAAACAAGCAGCAGTTGATTTAGGACTGA
AGCAAGGAAAAGTAGTTATTACAGTTGGTGATGGACCAGGTTTTTATACAACTCGAATTC
TTTCAACTATGGTTGCTGAGGGCATGTTGATAATGCAAGAAGGTGTCGATCCAAAGGACA
TTGATAAACTCACAAAACAATTTGGTTTCCCAGTTGGTCTTGCTACTTTAATTGATGAAG
TGGGAATTGATGTTGGTATGCACATTTTCAAAGACTTGCAAGCAGCTTTTGGTGATCGTT
TATCAGGCGGTGACGCAAATATCTCAGTAGATTTGGTTAGTTAAAGCAGGTTTCTTGGGA
AGAAAATCAGGAAAAGGAATTTTCGTTTATGATGGTCAAACGAAAGGAAGTCGTGAAGTC
AATCCTGAGGCATTAGCAATCATTAAACAAAAATACGCTTTGGTGTCCAAAGGAGCAAAT
CAACCAGAAGATTTACAATTGAGAATGGTGTCTAGATTTATTAATGAAGCCGTAATGTGT
CTTGAAGAAAAGATTTTGCACAGTCCATTAGAAGGTGATATTGGTGCCGTATTTGGTCTC
GGATTCCCACCTTTTTCCGGTGGTCCATTTAAATTTGTTGATACATTCGGAGCTGATAAG
CTTGTAAACAAAATGCTATCATATGCAGAGCTCTATGGAAGACCGTTTCAACCAGCTCAA
ACATTACTTGATATGGCAAAAGATTCATCAAAGAAATTTTATAAATAA
>g9117.t64 Gene=g9117 Length=253
MGAGIVQVTVDKGYNVIMKDATEAGLSRGIGQIQKGLDGAVKRKKISSLDKDKIMSNLTS
TLSYEPFRNADIVIEAVFENLDIKHRVIKEMESVIPEHCIIATNTSALPITKIAAGSSRP
DKVIGMHYFSPVDKMQLLEIITHPGTSLEAKQAAVDLGLKQGKVVITVGDGPGFYTTRIL
STMVAEGMLIMQEGVDPKDIDKLTKQFGFPVGLATLIDEVGIDVGMHIFKDLQAAFGDRL
SGGDANISVDLVS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g9117.t64 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 174 | 0 |
| 7 | g9117.t64 | Gene3D | G3DSA:1.10.1040.50 | - | 175 | 253 | 0 |
| 3 | g9117.t64 | PANTHER | PTHR43612 | TRIFUNCTIONAL ENZYME SUBUNIT ALPHA | 1 | 247 | 0 |
| 8 | g9117.t64 | PIRSF | PIRSF000105 | HCDH | 1 | 242 | 0 |
| 2 | g9117.t64 | Pfam | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | 1 | 170 | 0 |
| 1 | g9117.t64 | Pfam | PF00725 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | 173 | 241 | 0 |
| 4 | g9117.t64 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 1 | 172 | 0 |
| 5 | g9117.t64 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 172 | 238 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0070403 | NAD+ binding | MF |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
