General information for g9117.t68
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Trifunctional enzyme subunit alpha, mitochondrial.
Parent gene
- The parent gene g9117 is located on chr_1: 221472..222354 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9117 | g9117.t68 | TTS | g9117.t68 | 220513 | 220513 |
| chr_1 | g9117 | g9117.t68 | isoform | g9117.t68 | 220550 | 222072 |
| chr_1 | g9117 | g9117.t68 | exon | g9117.t68.exon1 | 220550 | 220702 |
| chr_1 | g9117 | g9117.t68 | cds | g9117.t68.CDS1 | 220551 | 220702 |
| chr_1 | g9117 | g9117.t68 | exon | g9117.t68.exon2 | 220766 | 221272 |
| chr_1 | g9117 | g9117.t68 | cds | g9117.t68.CDS2 | 220766 | 221272 |
| chr_1 | g9117 | g9117.t68 | exon | g9117.t68.exon3 | 221337 | 221401 |
| chr_1 | g9117 | g9117.t68 | cds | g9117.t68.CDS3 | 221337 | 221401 |
| chr_1 | g9117 | g9117.t68 | exon | g9117.t68.exon4 | 221472 | 221877 |
| chr_1 | g9117 | g9117.t68 | cds | g9117.t68.CDS4 | 221472 | 221632 |
| chr_1 | g9117 | g9117.t68 | exon | g9117.t68.exon5 | 221999 | 222072 |
| chr_1 | g9117 | g9117.t68 | TSS | g9117.t68 | 222169 | 222169 |
Sequences
>g9117.t68 Gene=g9117 Length=1205
ATGGCTAGTTTGCGAGTTAAAGGATTTTTATCTACTATTACACGAGTGAAGAGAATTGGT
CTGCAGAATTGTAACTTCTATCAACCAATTTAATCGTAATTGTTCATCGACGTCGGCAAA
AAATATCAAAACGTCCATTGTTGATAATGTACTTGTAATCAAATTAGATCAACCAGGCTC
AAAAGTTAATACTTTAGGAAAACAAATTACTAATGAATTTGAAGCAGTTCTTAAAGAGTT
TGAGACAAATCCAGCTGTAAAGTCTGCTGTTCTCATATCTGGCAAGCCATCTTGTTTCGT
AGCTGGCGCAGATATAACAATGTTAGAAGAATGTAAAACAGAAAATGATGCCAGGAAGAT
CAGTCATGAAGCTCAAATTATGTTTGATCGAATGGAAAAGTCAAATAAGCCCATTGTCTG
TGCAATTCATGGAACATGTTTTGGAGGCGGATTAGAATTGGCGCTAGCATGCCATTATAG
AATCGCAACAAAAAGTAAAAAAACGGGTTTAGCTCTTCCTGAAGTTATGCTTGGCTTGTT
ACCTGGTGCTGGAGGAACGCAACGTGTTCAAAAATTAACATCAATCCCTACCACACTCGA
TTTGGCACTTACTGGAAAAACTGTAAAGGCTGATAAAGCAAAAAAAATTGGCTTAGTTGA
TTTGCTTGTTGATGAATTGGGTCCAGGCTTGCACGATCCTTCAAAAAACACTTTGAAATA
TCTTGAGGATACAGCAATTAAAGTTGCCAAAGATCTTGCAAGTGGTACAATCAAAGTGAA
TCGTCAAAAGACTGGTGTAATCAATAAGATTACAGAAACAGCAATGGGATTTGATTTTGT
AAAAGATTTTATTTTTAAAAAAGCACGTCAACAAGTTATGAAAATGAGTAATGGTCTCTA
TCCTGCACCTCTCAAGATTTTGGAAGTAGTTCGTACTGGTGCAGATAAAGGTTTTGAAGC
AGGACTGGAAGCTGAAAGAAATGCTTTTGGAACATTATCTCAAACACCACAATCTAAAGG
ACTGATTTCACTTTTTAGAGGACAAACAGAATGCAAGAAAAATCGTTTTGGAAATCCCAG
TCGACCTGTAAAAAATGTTGCTGTATTGGGCGCTGGATTGATGGGGGCTGGTATTGTTCA
AGTAACAGTTGATAAAGGCTATAATGTCATAATGAAAGATGCAACAGAGGCTGGTTTATC
AAGAG
>g9117.t68 Gene=g9117 Length=295
MLEECKTENDARKISHEAQIMFDRMEKSNKPIVCAIHGTCFGGGLELALACHYRIATKSK
KTGLALPEVMLGLLPGAGGTQRVQKLTSIPTTLDLALTGKTVKADKAKKIGLVDLLVDEL
GPGLHDPSKNTLKYLEDTAIKVAKDLASGTIKVNRQKTGVINKITETAMGFDFVKDFIFK
KARQQVMKMSNGLYPAPLKILEVVRTGADKGFEAGLEAERNAFGTLSQTPQSKGLISLFR
GQTECKKNRFGNPSRPVKNVAVLGAGLMGAGIVQVTVDKGYNVIMKDATEAGLSR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g9117.t68 | CDD | cd06558 | crotonase-like | 8 | 119 | 0e+00 |
| 7 | g9117.t68 | Gene3D | G3DSA:3.90.226.10 | - | 1 | 248 | 0e+00 |
| 6 | g9117.t68 | Gene3D | G3DSA:3.40.50.720 | - | 249 | 295 | 0e+00 |
| 3 | g9117.t68 | PANTHER | PTHR43612 | TRIFUNCTIONAL ENZYME SUBUNIT ALPHA | 1 | 295 | 0e+00 |
| 2 | g9117.t68 | Pfam | PF00378 | Enoyl-CoA hydratase/isomerase | 9 | 119 | 0e+00 |
| 1 | g9117.t68 | Pfam | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | 259 | 293 | 1e-06 |
| 4 | g9117.t68 | SUPERFAMILY | SSF52096 | ClpP/crotonase | 8 | 247 | 0e+00 |
| 5 | g9117.t68 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 256 | 293 | 8e-07 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0070403 | NAD+ binding | MF |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed