General information for g9189.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glycogen synthase kinase-3.
Parent gene
- The parent gene g9189 is located on chr_1: 688676..689741 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9189 | g9189.t1 | isoform | g9189.t1 | 688676 | 689741 |
| chr_1 | g9189 | g9189.t1 | exon | g9189.t1.exon1 | 688676 | 689267 |
| chr_1 | g9189 | g9189.t1 | cds | g9189.t1.CDS1 | 688676 | 689267 |
| chr_1 | g9189 | g9189.t1 | exon | g9189.t1.exon2 | 689338 | 689741 |
| chr_1 | g9189 | g9189.t1 | cds | g9189.t1.CDS2 | 689338 | 689741 |
| chr_1 | g9189 | g9189.t1 | TSS | g9189.t1 | NA | NA |
| chr_1 | g9189 | g9189.t1 | TTS | g9189.t1 | NA | NA |
Sequences
>g9189.t1 Gene=g9189 Length=996
ATGATTATTTATTCGGCAAAAGATGATAAAGAAACGGACGTGGTTGTCGAGCTCTTAAGT
GAAATAGGAAAAGGAGCATTTGCTAAAGTGTTTTGTGCCAAATTAAACAATAGTAAATTT
GTTGCGGTCAAGCAAGTTTCAGCTTCATTTATGCCTGAGCTCGAAATAATGAGAAAAATC
GCTTGTCATCCAAACATTCGAAAATTTTATTATTATTATTACACTACAAAGAACAATGAC
ACTAAGATTTTTCGAAATATTAATTTCATTCTTGAATTAATGCCAATGGATCTTTTAACC
TATATTAGAGAATTATATGCAAAAGGATTACAAATGAAGACTTTACAGTTAAAAGCTTTT
GCTTATCAGCTTTTTAAATCATTAGGCTATCTCCATTCGTTAAATATTTGTCATCGTGAC
ATAAAGCCTGCGAACATTCTTATACGGTTAGAGACATACGAGCTTAAATTATCCGATTTT
GGTTGTGCAAAAGAACTTTCAGAGAATATGCCGAGTACAAATTACATTTGCTCTCGTTAT
TATCGCGCTCCTGAACTTGTGTTCGGTGCTACTCAATACTCAAATAAGATAGATATTTGG
AGTGCTGGTTGTTGTATTGTAGAAATGTTAACATTAGATGTTTTATTTTTAGCTGATTCT
AATATTGAATTGATAAATCAGCATGTACGAATGATTGGAATACCATCACAAAGCGAAATG
AATTTGATGAAAGCAAATTTCAAAAATAGTGCGTACATTCCTAAAGTCTCTAATAAGAGA
TGGCCAAAAAAATTATTAATTTTGGCACCACCTAAACTTTTGGAATTCCTTTCAATGATT
TTTTTGTACAATCCAAACAAAAGAATGAATGGATATGAAGCATGTGGTCATAGCTTTTTT
AATGAGCTCAGAGGAATCGATAGTGATGAAGATAAATGGAATTCTAATTTAACTGAAGCT
GAAATCACTGCAATCAATACTTTTTTGGCAATTTAA
>g9189.t1 Gene=g9189 Length=331
MIIYSAKDDKETDVVVELLSEIGKGAFAKVFCAKLNNSKFVAVKQVSASFMPELEIMRKI
ACHPNIRKFYYYYYTTKNNDTKIFRNINFILELMPMDLLTYIRELYAKGLQMKTLQLKAF
AYQLFKSLGYLHSLNICHRDIKPANILIRLETYELKLSDFGCAKELSENMPSTNYICSRY
YRAPELVFGATQYSNKIDIWSAGCCIVEMLTLDVLFLADSNIELINQHVRMIGIPSQSEM
NLMKANFKNSAYIPKVSNKRWPKKLLILAPPKLLEFLSMIFLYNPNKRMNGYEACGHSFF
NELRGIDSDEDKWNSNLTEAEITAINTFLAI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g9189.t1 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 3 | 95 | 1.2E-13 |
| 6 | g9189.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 98 | 327 | 5.0E-56 |
| 2 | g9189.t1 | PANTHER | PTHR24057 | GLYCOGEN SYNTHASE KINASE-3 ALPHA | 13 | 305 | 1.1E-81 |
| 3 | g9189.t1 | PANTHER | PTHR24057:SF0 | PROTEIN KINASE SHAGGY-RELATED | 13 | 305 | 1.1E-81 |
| 1 | g9189.t1 | Pfam | PF00069 | Protein kinase domain | 18 | 300 | 1.1E-53 |
| 7 | g9189.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 264 | - |
| 9 | g9189.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 265 | 283 | - |
| 8 | g9189.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 284 | 331 | - |
| 11 | g9189.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 22 | 44 | - |
| 10 | g9189.t1 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 136 | 148 | - |
| 13 | g9189.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 16 | 300 | 37.404 |
| 12 | g9189.t1 | SMART | SM00220 | serkin_6 | 16 | 300 | 2.4E-70 |
| 4 | g9189.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 17 | 303 | 2.97E-70 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
