General information for g919.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Chymotrypsin-1.
Parent gene
- The parent gene g919 is located on chr_3: 6862146..6863474 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g919 | g919.t1 | TTS | g919.t1 | 6862025 | 6862025 |
| chr_3 | g919 | g919.t1 | isoform | g919.t1 | 6862146 | 6863474 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon1 | 6862146 | 6862208 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS1 | 6862146 | 6862208 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon2 | 6862262 | 6862515 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS2 | 6862262 | 6862515 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon3 | 6862683 | 6862789 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS3 | 6862683 | 6862789 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon4 | 6862844 | 6862985 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS4 | 6862844 | 6862985 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon5 | 6863219 | 6863359 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS5 | 6863219 | 6863359 |
| chr_3 | g919 | g919.t1 | exon | g919.t1.exon6 | 6863420 | 6863474 |
| chr_3 | g919 | g919.t1 | cds | g919.t1.CDS6 | 6863420 | 6863474 |
| chr_3 | g919 | g919.t1 | TSS | g919.t1 | 6863485 | 6863485 |
Sequences
>g919.t1 Gene=g919 Length=762
ATGTTCCTAAGAATTTTGACATTATTTTTGTGCTTTGCAGTTGTTCTTTCAGCTCCTCAA
CAAATTGAAAGGAAAATTTTAGGAGGTGAAGAAAATGCTTTAGGTGAAATTCCTTATGTT
GTTTCAATCACAATTTTTACTGGTTTACATATTTGTTCTGGTGCAATTATCAGTGATTGG
TGGACGATAACGGCAGCACATTGTATTTTTGGTCGAGGACCAAATACAGTTGTTGTTCGA
CCTGGAAGAATTCGTCTTGACGTAAATTCAATGGAAGATCGACAAGGAAGTGTTTTGATA
ACTCATCCAAATTATGTTGCCGAAATTTTAGAAAACGACATAGGATTGATTCAAGTTTCT
CGAGCATTTGTTTTCAATGTCAATATTCAACCAATCGCTTTGAGTGATAGTTTTGTGGGC
GGTGGAATTGCTGCTGCTGTATCAGGTTGGGGAACACTCACGCCTGGTGGAATTAATCAT
AATTTTCTTCTAACACTTCAAACTTCAACACTATCAAATGCTGATTGTCAATCACGTCAT
ACAAGTCAAAATGCAGCACTGATAAGAGATGATACAATTTGTACAAATAATCTAGTTGGT
GAAGGATTTTGTAATCGAGCTTTTGGGTCGCCTTTGGTCAGTGATTCAAAATTAATTGCT
ATCGCTTCATGGAATGTTCCTTGTGCTTTGGGCTATCCTGATGTTTATTCGAGAATTTTT
ACAAGTCTTGATTGGATAAGAACAGTAACTGGAATAAATTAA
>g919.t1 Gene=g919 Length=253
MFLRILTLFLCFAVVLSAPQQIERKILGGEENALGEIPYVVSITIFTGLHICSGAIISDW
WTITAAHCIFGRGPNTVVVRPGRIRLDVNSMEDRQGSVLITHPNYVAEILENDIGLIQVS
RAFVFNVNIQPIALSDSFVGGGIAAAVSGWGTLTPGGINHNFLLTLQTSTLSNADCQSRH
TSQNAALIRDDTICTNNLVGEGFCNRAFGSPLVSDSKLIAIASWNVPCALGYPDVYSRIF
TSLDWIRTVTGIN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g919.t1 | CDD | cd00190 | Tryp_SPc | 26 | 249 | 3.38978E-51 |
| 9 | g919.t1 | Gene3D | G3DSA:2.40.10.10 | - | 28 | 238 | 7.0E-46 |
| 10 | g919.t1 | Gene3D | G3DSA:2.40.10.10 | - | 38 | 246 | 7.0E-46 |
| 2 | g919.t1 | PANTHER | PTHR24276 | POLYSERASE-RELATED | 9 | 248 | 4.5E-44 |
| 3 | g919.t1 | PANTHER | PTHR24276:SF78 | AT20289P-RELATED | 9 | 248 | 4.5E-44 |
| 6 | g919.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 53 | 68 | 3.2E-6 |
| 4 | g919.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 109 | 123 | 3.2E-6 |
| 5 | g919.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 201 | 213 | 3.2E-6 |
| 1 | g919.t1 | Pfam | PF00089 | Trypsin | 26 | 246 | 2.9E-37 |
| 12 | g919.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 24 | - |
| 13 | g919.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 14 | g919.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 16 | - |
| 15 | g919.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 24 | - |
| 11 | g919.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 25 | 253 | - |
| 18 | g919.t1 | ProSitePatterns | PS00134 | Serine proteases, trypsin family, histidine active site. | 63 | 68 | - |
| 19 | g919.t1 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 26 | 251 | 23.741 |
| 17 | g919.t1 | SMART | SM00020 | trypsin_2 | 25 | 246 | 5.1E-37 |
| 7 | g919.t1 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 1 | 252 | 2.91E-57 |
| 8 | g919.t1 | SignalP_EUK | SignalP-TM | SignalP-TM | 1 | 17 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed