General information for g9426.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glycosylphosphatidylinositol anchor attachment 1 protein.
Parent gene
- The parent gene g9426 is located on chr_1: 2858247..2859684 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9426 | g9426.t1 | TTS | g9426.t1 | 2857563 | 2857563 |
| chr_1 | g9426 | g9426.t1 | isoform | g9426.t1 | 2857642 | 2859684 |
| chr_1 | g9426 | g9426.t1 | exon | g9426.t1.exon1 | 2857642 | 2859416 |
| chr_1 | g9426 | g9426.t1 | cds | g9426.t1.CDS1 | 2857642 | 2859416 |
| chr_1 | g9426 | g9426.t1 | exon | g9426.t1.exon2 | 2859498 | 2859684 |
| chr_1 | g9426 | g9426.t1 | cds | g9426.t1.CDS2 | 2859498 | 2859684 |
| chr_1 | g9426 | g9426.t1 | TSS | g9426.t1 | 2859753 | 2859753 |
Sequences
>g9426.t1 Gene=g9426 Length=1962
ATGGGTATTTTATCAAATCCTTCAATAGGTGCACATGAAAAGAAAACAAAGTACATTACA
ATTATTAATAAATACTCAAATTTATTTTGTTTTTTATTATATTTAATTGGTTTCGGCTGG
TTTTGTGCTTTAAGTTTTCCGCAATTTCAGTCAAATACTTATTTCTCTGAAAATGCATTA
TTACCAGGTCTTGTATTATCAGAATTAAAAATGGACAGTGTCAATTTGGCAAAAACTTAT
TTAAATGAATTAGAACATGAGAGAACAAGTCACAAATCAAACATTCCTTACCCATGGATG
CAAGCAAAAATGAAGCAAATCGGATTAAAAACTTACATTCACAATTTCACACTCAATTAT
CCTTTTGGAGGAGGTAAAAGGTTTGAAGGAAAAAATATTTATGGAATTTTGAGAGGTCCT
CGTATCGGTGCAACTGAATCAATTGTCATCAGTGTTCCTTATCGTCCACCAAACACAGCT
CATACTTCTATCACTGCTAGCGTTCCCTTGATTTTGGCATTTGCAGACTTTGCTAGAAGG
CAAAAGTATTGGTCAAAAGATATTATTTTCCTTGTTACTGATCAAGAACAATTAGGCATG
CAAGCATTTCTAGAGGCATATTATGGTGAAGATGAAAATAATATTCTTGATTCTGGAACT
CTTTATGGAAAAGCTGGAAGTATAGTTGCAGCCATAAATATGGAAATTCAAGATTTTGAT
GTAGATTTTAATAGTTTAAAAATTGAAGGACTTAATGGTCAACTGCCTAATTTAGATTTG
CATAATCTTGTTGTGAAACTTTCACATAAAAATGGCATTCCAATTGGCTACAAAACAAAA
ATGAGTGAGCATCCTCGTGACGATGTGATTGCAAATTTCTTCAGTTTACTCTCAATGATG
TGGACACAATCGAGTGGTGTACCAAATGGAAATCACGGATTATTTCATAAATATGGCATT
GAAGCACTTACAATTGAAGCTGTTAAAAGAGAGACAAGTGTGAAAAACAATAATGTTCAT
CATAAAATTATGGCATTGTTAAAAATCATTGAAGGCATCAGTCGATCTCTAAACAATCTT
TTGGAAAGATTTCATCAAAGTTTCTTCTTTTATGTGATTGTATCCGCTGATCGTTTCATT
TCGATTGGTGATTACATGCCTAGTGTTGGTTTAATGTCTGCAAGTTTGCTTATCAAATCT
TTTCTCTTATGGCTTATTGCAAATAACAAAAATGAAGATGATGAACAAGAAAATGAAAAT
AAGGAAGAAGAGGACAAAATTGTAATCGTAAGAAAATCAAAAACAACCATTGACTACATT
AAAATAGGAACAATTATCTTATGTTCGCATATTGTTGGAGTTGGTGCATTGTTAATTACA
ACAAACAAATTTATTCATGATTATCTCTTCTCTATGAACATTCCAACACAAACTGGTATT
TTCTACTCAATCATCTTCATAATTGCAGTGAGTTTATTAATGCCAAAATTTTTAAGACTG
AATGTTATTGATGCTCAATATCTTAACATTGTTCTCTTAATTGAACTTGGAACTATGCTT
CTTTCTGTAAGCATGTTAAATTTCTCACTTGGATTCTTCTTGTGTGTTTTTATTACACCA
TTTGCTATTTTAATTAACATTCAAGAGAACTCACGAAGAAATTTATTAAAATTTCTAATA
AGAAGTCTAATTCATCTAATTATTCATCCAATCACAGTTTTATATGGAATTATTTGTTTA
TTAAGCTACATAGCATTCAATGAAATGAATTTCAACTATATCGTTGATAAATCATTCACA
GCAACAATTGATGCAATTACATTTGCTGTCGTTGATTCTCTCATTTATGGAAATTGGTTG
TTTGATTTAACATTTCTAATTTTATTACCTTGCTGGATAATGCTATGGATTCTAAATTTT
TCAAAACCAATTGAAAAGAAGAACAAAGACAAGTCAGAATAA
>g9426.t1 Gene=g9426 Length=653
MGILSNPSIGAHEKKTKYITIINKYSNLFCFLLYLIGFGWFCALSFPQFQSNTYFSENAL
LPGLVLSELKMDSVNLAKTYLNELEHERTSHKSNIPYPWMQAKMKQIGLKTYIHNFTLNY
PFGGGKRFEGKNIYGILRGPRIGATESIVISVPYRPPNTAHTSITASVPLILAFADFARR
QKYWSKDIIFLVTDQEQLGMQAFLEAYYGEDENNILDSGTLYGKAGSIVAAINMEIQDFD
VDFNSLKIEGLNGQLPNLDLHNLVVKLSHKNGIPIGYKTKMSEHPRDDVIANFFSLLSMM
WTQSSGVPNGNHGLFHKYGIEALTIEAVKRETSVKNNNVHHKIMALLKIIEGISRSLNNL
LERFHQSFFFYVIVSADRFISIGDYMPSVGLMSASLLIKSFLLWLIANNKNEDDEQENEN
KEEEDKIVIVRKSKTTIDYIKIGTIILCSHIVGVGALLITTNKFIHDYLFSMNIPTQTGI
FYSIIFIIAVSLLMPKFLRLNVIDAQYLNIVLLIELGTMLLSVSMLNFSLGFFLCVFITP
FAILINIQENSRRNLLKFLIRSLIHLIIHPITVLYGIICLLSYIAFNEMNFNYIVDKSFT
ATIDAITFAVVDSLIYGNWLFDLTFLILLPCWIMLWILNFSKPIEKKNKDKSE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g9426.t1 | Coils | Coil | Coil | 406 | 426 | - |
| 11 | g9426.t1 | Gene3D | G3DSA:3.40.630.10 | Zn peptidases | 85 | 351 | 2.1E-5 |
| 2 | g9426.t1 | PANTHER | PTHR13304 | GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN | 1 | 640 | 3.2E-143 |
| 30 | g9426.t1 | PIRSF | PIRSF036762 | GAA1 | 1 | 653 | 2.3E-162 |
| 1 | g9426.t1 | Pfam | PF04114 | Gaa1-like, GPI transamidase component | 129 | 636 | 5.0E-147 |
| 17 | g9426.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 24 | - |
| 22 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 46 | - |
| 21 | g9426.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 47 | 384 | - |
| 28 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 385 | 407 | - |
| 13 | g9426.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 408 | 438 | - |
| 26 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 439 | 459 | - |
| 20 | g9426.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 460 | 478 | - |
| 25 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 479 | 498 | - |
| 16 | g9426.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 499 | 509 | - |
| 27 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 510 | 543 | - |
| 19 | g9426.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 544 | 562 | - |
| 23 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 563 | 586 | - |
| 14 | g9426.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 587 | 597 | - |
| 24 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 598 | 617 | - |
| 18 | g9426.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 618 | 622 | - |
| 29 | g9426.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 623 | 641 | - |
| 15 | g9426.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 642 | 653 | - |
| 9 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 47 | - |
| 5 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 385 | 407 | - |
| 3 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 439 | 461 | - |
| 6 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 476 | 494 | - |
| 7 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 507 | 526 | - |
| 10 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 530 | 547 | - |
| 8 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 564 | 586 | - |
| 4 | g9426.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 619 | 641 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0042765 | GPI-anchor transamidase complex | CC |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K05289 (GPI-anchor transamidase subunit GAA1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
