Gene loci information

Transcript annotation

  • This transcript has been annotated as [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9428 g9428.t10 TSS g9428.t10 2861344 2861344
chr_1 g9428 g9428.t10 isoform g9428.t10 2861647 2868793
chr_1 g9428 g9428.t10 exon g9428.t10.exon1 2861647 2861710
chr_1 g9428 g9428.t10 cds g9428.t10.CDS1 2861647 2861710
chr_1 g9428 g9428.t10 exon g9428.t10.exon2 2865740 2865984
chr_1 g9428 g9428.t10 cds g9428.t10.CDS2 2865740 2865984
chr_1 g9428 g9428.t10 exon g9428.t10.exon3 2866042 2866189
chr_1 g9428 g9428.t10 cds g9428.t10.CDS3 2866042 2866189
chr_1 g9428 g9428.t10 exon g9428.t10.exon4 2866255 2866422
chr_1 g9428 g9428.t10 cds g9428.t10.CDS4 2866255 2866422
chr_1 g9428 g9428.t10 exon g9428.t10.exon5 2866490 2866780
chr_1 g9428 g9428.t10 cds g9428.t10.CDS5 2866490 2866780
chr_1 g9428 g9428.t10 exon g9428.t10.exon6 2867240 2867349
chr_1 g9428 g9428.t10 cds g9428.t10.CDS6 2867240 2867349
chr_1 g9428 g9428.t10 exon g9428.t10.exon7 2867405 2867503
chr_1 g9428 g9428.t10 cds g9428.t10.CDS7 2867405 2867503
chr_1 g9428 g9428.t10 exon g9428.t10.exon8 2867813 2867894
chr_1 g9428 g9428.t10 cds g9428.t10.CDS8 2867813 2867839
chr_1 g9428 g9428.t10 exon g9428.t10.exon9 2868364 2868793
chr_1 g9428 g9428.t10 TTS g9428.t10 2868794 2868794

Sequences

>g9428.t10 Gene=g9428 Length=1637
ATGTTAGATTTCTACTCTCAATTTAATCCTTCACCATTGTCTATAAAGCAATTTCTTGAT
TTCGGAATGAATGCATGCGAGCGAAAATCGTTCGTGTTTTTACGCAAAGAACTGCCCGTT
CGTTTAGCGAACATTATGAAAGAAATTGCTTTACTGCCAGACAGTCTTCTCAGAACACAG
TCGGTTGGCCTCGTTAGTAATTGGTATGCAAAAAGCTTCGAAGAAGTTCTTCAGTTTGAA
CGTTCTGAACCGACACAAAGTAATCTGGAAAAGTTCTGTTCCACACTTATCCACATTCGA
GATCGTCATGCTGATGTTGTTCAAACGATGGCTCATGGAATTATTGAAATGAAGGAAGCT
CAAAATATTGAACCAGGAATGGAAACAAGCATTCAATATTTCTTAGATCGTTTCTACATG
TCGAGAATTTCCATTCGAATGCTCATCAATCAGCACACGATCCTTTTTGGAGAGCTGCCT
CAACAGACGCATCAACAGCATGTCGGTTGCATTGAAATTGATTTCGATCCAAAAGTTGTT
GTTCGTGATGCGTATGAAAACGCAAGATATCTCTGTGATCAAAATTATTTAGGTTCACCA
GAAATTGAAATTATCGAACACAATGAAATGGAAAAGGGTCAACCAATAAAAATTGTATAT
GTGCCATCACATTTATATCACATTCTTTTTGAGTTGTTTAAAAACTCAATGAGAGCTGTT
ATGGAAACACATCAAGAAAGTGATTCAATTCCTCCGATTAAAGTAAGGATTGTAAATGGA
AAAGAAGATGTCAGTGTTAAAATTAGTGATTGCGGAGGTGGAATACCACGATCACAAGTC
GATCAACTTTTTAAGTACATGTACTCAACTGCTCCACATCCTTCAAAATCAGATGTTCAC
ACAGTTCCATTAGCTGGCTATGGATATGGTTTGCCTATTTCGCGTTTATATGCAAGATAC
TTTCATGGTGATATTTCACTGCTTTCCTGTGAAGGTTTTGGAACTGATGCAGTGATTTAT
TTAAAACGTTTATCTGATGAGGCAAATGAATTATTGCCAATTTTTAATAAAACAAGTTCA
AGATTTTATAAGGCATCTGTTCCAGCTGGAGATTGGTCAAATCAAAAATATGTAACTGGA
TATGGTTTTTAGTCAAATGATATAAAATATTATTTAAGCCCTGGAGGCACATGTGAAGAA
GAAAAGAAGCTCTGAGATGAATTCGACATTTAATCAATGGAAATTTGTAAAAAAAGGACA
GTAAGACAAAAAAAATAATATTTGAGAAATGACGTACCTAAAAAAATTTAAAATTCAACA
AACTTGACGCTTTTGAAAATAAAAAATAATTGGCATATGAAACACTAACATCATCAAAAA
GCGAAAATACGAAAAAAGTCCCCAGGAAATCTCGAATTGGAAAAAAAAATATTTTTTATG
CAAAGCTTATGCATTTTTCTAAAATTTTTCATACTTGTTAGTAGTATACACATACAGATA
CATATTGAATATTAGTTGATAAGAATGATTCACAAAAACGTGAAGATCGTAAAGCCTCAA
AAATAATTGAATGAATTCTTTTCATTTTTATGATGATGCACTAATTAGGCAGTAAATTAA
ATAAAAATAGCAAAACT

>g9428.t10 Gene=g9428 Length=383
MLDFYSQFNPSPLSIKQFLDFGMNACERKSFVFLRKELPVRLANIMKEIALLPDSLLRTQ
SVGLVSNWYAKSFEEVLQFERSEPTQSNLEKFCSTLIHIRDRHADVVQTMAHGIIEMKEA
QNIEPGMETSIQYFLDRFYMSRISIRMLINQHTILFGELPQQTHQQHVGCIEIDFDPKVV
VRDAYENARYLCDQNYLGSPEIEIIEHNEMEKGQPIKIVYVPSHLYHILFELFKNSMRAV
METHQESDSIPPIKVRIVNGKEDVSVKISDCGGGIPRSQVDQLFKYMYSTAPHPSKSDVH
TVPLAGYGYGLPISRLYARYFHGDISLLSCEGFGTDAVIYLKRLSDEANELLPIFNKTSS
RFYKASVPAGDWSNQKYVTGYGF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g9428.t10 CDD cd16929 HATPase_PDK-like 176 342 0.000
9 g9428.t10 Gene3D G3DSA:1.20.140.20 - 1 167 0.000
8 g9428.t10 Gene3D G3DSA:3.30.565.10 - 175 353 0.000
3 g9428.t10 PANTHER PTHR11947:SF14 [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL 2 367 0.000
4 g9428.t10 PANTHER PTHR11947 PYRUVATE DEHYDROGENASE KINASE 2 367 0.000
1 g9428.t10 Pfam PF10436 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase 12 172 0.000
2 g9428.t10 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 222 342 0.000
10 g9428.t10 ProSiteProfiles PS50109 Histidine kinase domain profile. 222 345 19.345
7 g9428.t10 SMART SM00387 HKATPase_4 220 345 0.000
5 g9428.t10 SUPERFAMILY SSF69012 alpha-ketoacid dehydrogenase kinase, N-terminal domain 2 156 0.000
6 g9428.t10 SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 206 352 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004672 protein kinase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values