General information for g9428.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial.
Parent gene
- The parent gene g9428 is located on chr_1: 2867799..2868793 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9428 | g9428.t8 | TSS | g9428.t8 | 2861344 | 2861344 |
| chr_1 | g9428 | g9428.t8 | isoform | g9428.t8 | 2861647 | 2868420 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon1 | 2861647 | 2861710 |
| chr_1 | g9428 | g9428.t8 | cds | g9428.t8.CDS1 | 2861647 | 2861710 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon2 | 2865740 | 2865984 |
| chr_1 | g9428 | g9428.t8 | cds | g9428.t8.CDS2 | 2865740 | 2865984 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon3 | 2866042 | 2866189 |
| chr_1 | g9428 | g9428.t8 | cds | g9428.t8.CDS3 | 2866042 | 2866189 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon4 | 2866255 | 2867349 |
| chr_1 | g9428 | g9428.t8 | cds | g9428.t8.CDS4 | 2866255 | 2866457 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon5 | 2867405 | 2867503 |
| chr_1 | g9428 | g9428.t8 | exon | g9428.t8.exon6 | 2868364 | 2868420 |
| chr_1 | g9428 | g9428.t8 | TTS | g9428.t8 | 2868794 | 2868794 |
Sequences
>g9428.t8 Gene=g9428 Length=1708
ATGTTAGATTTCTACTCTCAATTTAATCCTTCACCATTGTCTATAAAGCAATTTCTTGAT
TTCGGAATGAATGCATGCGAGCGAAAATCGTTCGTGTTTTTACGCAAAGAACTGCCCGTT
CGTTTAGCGAACATTATGAAAGAAATTGCTTTACTGCCAGACAGTCTTCTCAGAACACAG
TCGGTTGGCCTCGTTAGTAATTGGTATGCAAAAAGCTTCGAAGAAGTTCTTCAGTTTGAA
CGTTCTGAACCGACACAAAGTAATCTGGAAAAGTTCTGTTCCACACTTATCCACATTCGA
GATCGTCATGCTGATGTTGTTCAAACGATGGCTCATGGAATTATTGAAATGAAGGAAGCT
CAAAATATTGAACCAGGAATGGAAACAAGCATTCAATATTTCTTAGATCGTTTCTACATG
TCGAGAATTTCCATTCGAATGCTCATCAATCAGCACACGATCCTTTTTGGAGAGCTGCCT
CAACAGACGCATCAACAGCATGTCGGTTGCATTGAAATTGATTTCGATCCAAAAGTTGTT
GTTCGTGATGCGTATGAAAACGCAAGATATCTCTGTGATCAAAATTATTTAGGTTCACCA
GAAATTGAAATTATCGAACACAATGGTAAGTTTTTCTTTTGCATTTCTTTTTTTCTTTGA
TCTTCTTTGTACAGCTGAAATATAAATTTAAGAAATGGAAAAGGGTCAACCAATAAAAAT
TGTATATGTGCCATCACATTTATATCACATTCTTTTTGAGTTGTTTAAAAACTCAATGAG
AGCTGTTATGGAAACACATCAAGAAAGTGATTCAATTCCTCCGATTAAAGTAAGGATTGT
AAATGGAAAAGAAGATGTCAGTGTTAAAATTAGTGATTGCGGAGGTGGAATACCACGATC
ACAAGTCGATCAACTTTTTAAGTACATGTACTCAACTGCTCCACATCCTTCAAAATCAGA
TGTTCACACAGTTCCATTAGCTGGTAAAGATTTTCTTTATTATTTTATTTCATCAAAAAA
TTTAATTCTTAAACCAATTTTATACTCCCTAAAATTTTTATATAAAATAGAACCGCTATC
CGGTGAGCTATTGCTGCGTAGTTTTCAATTTACCCTTAATCATTCCTAATTTACATTTCA
TTTGATTTTAAAAACCACAACAAGTGTGTGTTTATGTCGTTACTATAAAAGTATATAAAT
TTTAATTAATTCTTGTGCACACACAAAAAGAGAAGAATATTAAATGAAATGTATCATTCT
CACTGAATGCACGTGACATTGAGTGTTTTGATTTACTCGTCTAACGTAGTGAAATTTAAT
ATTCGTAAATAATAGCATATACCTCAAAAATCTTCATTTGCTTTCTCGTTAATCGGAAGT
TTTACCTTGAAAAATTTATTTTATTTATATTTTCTTTATCTGTTTAATGAAAAAAATTCT
AGGCTATGGATATGGTTTGCCTATTTCGCGTTTATATGCAAGATACTTTCATGGTGATAT
TTCACTGCTTTCCTGTGAAGGTTTTGGAACTGATGCAGTGATTTATTTAAAACGTTTATC
TGATGAGGCAAATGAATTATTGCCAATTTTTAATAAAACAAGTTCAAGATTTTATAAGGC
ATCTGTTCCAGCTGGAGATTGGTCAAATCAAAGCTCTGAGATGAATTCGACATTTAATCA
ATGGAAATTTGTAAAAAAAGGACAGTAA
>g9428.t8 Gene=g9428 Length=219
MLDFYSQFNPSPLSIKQFLDFGMNACERKSFVFLRKELPVRLANIMKEIALLPDSLLRTQ
SVGLVSNWYAKSFEEVLQFERSEPTQSNLEKFCSTLIHIRDRHADVVQTMAHGIIEMKEA
QNIEPGMETSIQYFLDRFYMSRISIRMLINQHTILFGELPQQTHQQHVGCIEIDFDPKVV
VRDAYENARYLCDQNYLGSPEIEIIEHNGKFFFCISFFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g9428.t8 | Gene3D | G3DSA:1.20.140.20 | - | 1 | 168 | 0 |
| 2 | g9428.t8 | PANTHER | PTHR11947:SF22 | [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL | 3 | 211 | 0 |
| 3 | g9428.t8 | PANTHER | PTHR11947 | PYRUVATE DEHYDROGENASE KINASE | 3 | 211 | 0 |
| 1 | g9428.t8 | Pfam | PF10436 | Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase | 12 | 172 | 0 |
| 4 | g9428.t8 | SUPERFAMILY | SSF69012 | alpha-ketoacid dehydrogenase kinase, N-terminal domain | 2 | 156 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004672 | protein kinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
