General information for g9476.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Bis(5’-nucleosyl)-tetraphosphatase [asymmetrical].
Parent gene
- The parent gene g9476 is located on chr_1: 3507077..3507583 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9476 | g9476.t1 | TTS | g9476.t1 | 3507044 | 3507044 |
| chr_1 | g9476 | g9476.t1 | isoform | g9476.t1 | 3507077 | 3507583 |
| chr_1 | g9476 | g9476.t1 | exon | g9476.t1.exon1 | 3507077 | 3507406 |
| chr_1 | g9476 | g9476.t1 | cds | g9476.t1.CDS1 | 3507077 | 3507406 |
| chr_1 | g9476 | g9476.t1 | exon | g9476.t1.exon2 | 3507467 | 3507583 |
| chr_1 | g9476 | g9476.t1 | cds | g9476.t1.CDS2 | 3507467 | 3507583 |
| chr_1 | g9476 | g9476.t1 | TSS | g9476.t1 | 3507600 | 3507600 |
Sequences
>g9476.t1 Gene=g9476 Length=447
ATGGCAGCAAGAAGAGCAAGTGGATTTTTAATTTATCGTTTCTTTTCAAATGAAATTCAA
TATTTATTGCTAAGAGCGAGCTATGCTGGATATCACTGGACTCCACCAAAAGGACATGCT
CACTCAGGCGAATCCGATTTTGAAACAGCTTTAAGAGAAACTCGTGAAGAAACTGGATAT
ATTGAAAAAGATCTCATCATTTATAAGGATATCAGTAGAACTCTAAATTATCGAGTGAAA
AAGAAACCAAAAGTTGTCACTTATTTTCTTGCACAACTCAAAGATCCTTTTCTTATGCCC
ATTTTGTCAGAAGAACATACAGAGTTTAAGTATTTAACTAAAAGAGAAACAATCCTCCTG
TCAGGTTATAAGAATTTCGGAGAAATGATAGAATATTTCGATAAAGAAATCAGAAAAATC
CATAGCAATGCACAAATTAATTTGTAA
>g9476.t1 Gene=g9476 Length=148
MAARRASGFLIYRFFSNEIQYLLLRASYAGYHWTPPKGHAHSGESDFETALRETREETGY
IEKDLIIYKDISRTLNYRVKKKPKVVTYFLAQLKDPFLMPILSEEHTEFKYLTKRETILL
SGYKNFGEMIEYFDKEIRKIHSNAQINL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g9476.t1 | CDD | cd03428 | Ap4A_hydrolase_human_like | 5 | 135 | 2.04267E-47 |
| 9 | g9476.t1 | Gene3D | G3DSA:3.90.79.10 | Nucleoside Triphosphate Pyrophosphohydrolase | 2 | 140 | 4.8E-30 |
| 2 | g9476.t1 | PANTHER | PTHR21340:SF0 | BIS(5’-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] | 5 | 139 | 6.3E-28 |
| 3 | g9476.t1 | PANTHER | PTHR21340 | DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT | 5 | 139 | 6.3E-28 |
| 4 | g9476.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 19 | 37 | 6.6E-12 |
| 6 | g9476.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 64 | 85 | 6.6E-12 |
| 7 | g9476.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 85 | 103 | 6.6E-12 |
| 5 | g9476.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 105 | 123 | 6.6E-12 |
| 1 | g9476.t1 | Pfam | PF00293 | NUDIX domain | 8 | 120 | 5.4E-14 |
| 11 | g9476.t1 | ProSitePatterns | PS00893 | Nudix box signature. | 38 | 59 | - |
| 12 | g9476.t1 | ProSiteProfiles | PS51462 | Nudix hydrolase domain profile. | 2 | 137 | 12.446 |
| 8 | g9476.t1 | SUPERFAMILY | SSF55811 | Nudix | 4 | 137 | 8.12E-21 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0008796 | bis(5’-nucleosyl)-tetraphosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01518 (bis(5’-nucleosidyl)-tetraphosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed