General information for g9569.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome regulatory subunit 7.
Parent gene
- The parent gene g9569 is located on chr_1: 4075062..4075622 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9569 | g9569.t10 | TTS | g9569.t10 | 4074061 | 4074061 |
| chr_1 | g9569 | g9569.t10 | isoform | g9569.t10 | 4074131 | 4075622 |
| chr_1 | g9569 | g9569.t10 | exon | g9569.t10.exon1 | 4074131 | 4074766 |
| chr_1 | g9569 | g9569.t10 | cds | g9569.t10.CDS1 | 4074131 | 4074766 |
| chr_1 | g9569 | g9569.t10 | exon | g9569.t10.exon2 | 4074824 | 4075622 |
| chr_1 | g9569 | g9569.t10 | cds | g9569.t10.CDS2 | 4074824 | 4074967 |
| chr_1 | g9569 | g9569.t10 | TSS | g9569.t10 | 4075709 | 4075709 |
Sequences
>g9569.t10 Gene=g9569 Length=1435
ATGCCGGATCATTTAGGTGATGATATGCGTAAGGTGAAAGTGGACGATAAGGAAAAAGAT
GAGCCAGTAATAAAAGGTAATTTTCACAAAAATATTTTTTGTCAAGTCATTCAAAGATTT
TCTTTTCATTTTTTTCAAAACAGATCTCGATGAAGGAGATATTGAGCTTTTAAAGACTTA
TGGACAGGGACAGTATCATAAAAGTATCAAACAAATTGAAGATGATATCCAAAAGGCAAT
TAAACAAGTTAATGAACTCACTGGAATCAAAGAAAGTGACACTGGTCTTGCTCCTCCAGC
TTTGTGGGATTTAGCGTATGTAAATTAACTTATATTGATGTTCTTTATATTTAAATATTG
TCTTTTTATAGTGCTGATAAACAAACACTTCAGAATGAGCAACCATTACAAGTAGCTCGC
TGTACAAAAATTATTAATGCGGATTCGGATGATCCTAAATATATCATCAATGTTAAGCAA
TTTGCAAAATTTGTAGTTGATCTTGCTGACTCAGTTGCACCAACAGATATTGAAGAAGGA
ATGCGTGTGGGTGTTGATAGAAATAAATATCAAATTCATATTCCATTGCCTCCGAAAATT
GATCCAACTGTTACAATGATGCAAGTTGAAGATAAACCAGATGTCACTTACTCAGATGTT
GGAGGATGTAAAGAACAGATTGAGAAACTTAGAGAAGTTGTTGAAACACCTCTCTTGCAT
CCAGAAAAGTTTGTCACACTCGGTATTGAACCACCAAAAGGCGTGCTTCTTTTTGGACCA
CCTGGAACTGGCAAGGTTTACACTATGTGCAAGAGCAGTTGCAAATCGTACTGATGCTTG
TTTTATTCGTGTAATTGGATCTGAGTTGGTTCAGAAATATGTCGGTGAAGGAGCGAGAAT
GGTTCGCGAATTATTTGAAATGGCACGCAGTAAAAAAGCTTGTCTCATCTTTTTCGATGA
AATTGATGCTATTGGTGGTGCACGTTTTGACGATGGTGCAGGAGGAGATAATGAAGTTCA
AAGAACTATGTTGGAACTTATTAATCAACTTGATGGTTTTGATCCTCGTGGTAATATCAA
AGTTTTGATGGCTACAAATCGTCCTGATACTTTAGATCCTGCATTAATGCGTCCTGGTCG
TCTCGATAGAAAAGTTGAATTTGGCTTACCTGACCTCGAAGGAAGAGCTCACATTTTTAA
AATTCATGCTCGTTCAATGTCTGTTGAGCGTGATATTCGCTTTGAATTGCTTGCTCGATT
ATGTCCTAATTCAACTGGTGCTGAAATTCGATCAGTTTGCACAGAAGCTGGCATGTTTGC
TATTCGTGCACGACGTAAAGTTGCAACAGAGAAAGATTTCCTTGAAGCTGTGAACAAAGT
CATCAAGAGCTACGCCAAATTCTCAGCTACTCCACGTTACATGACTTACAATTAA
>g9569.t10 Gene=g9569 Length=259
MLEDVKNRLRNLEKLLKHLSCIQKSLSHSVLNHQKACFFLDHLELARFTLCARAVANRTD
ACFIRVIGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGAGGDNE
VQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDLEGRAHI
FKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVN
KVIKSYAKFSATPRYMTYN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g9569.t10 | CDD | cd00009 | AAA | 49 | 171 | 4.411E-15 |
| 8 | g9569.t10 | Coils | Coil | Coil | 2 | 22 | - |
| 6 | g9569.t10 | Gene3D | G3DSA:3.40.50.300 | - | 49 | 170 | 2.3E-39 |
| 7 | g9569.t10 | Gene3D | G3DSA:1.10.8.60 | - | 172 | 244 | 3.7E-23 |
| 3 | g9569.t10 | PANTHER | PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | 49 | 257 | 3.9E-132 |
| 4 | g9569.t10 | PANTHER | PTHR23073:SF13 | 26S PROTEASOME REGULATORY SUBUNIT 7 | 49 | 257 | 3.9E-132 |
| 1 | g9569.t10 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | 49 | 170 | 5.3E-31 |
| 2 | g9569.t10 | Pfam | PF17862 | AAA+ lid domain | 193 | 237 | 5.4E-9 |
| 10 | g9569.t10 | ProSitePatterns | PS00674 | AAA-protein family signature. | 141 | 159 | - |
| 11 | g9569.t10 | SMART | SM00382 | AAA_5 | 44 | 173 | 1.1E-5 |
| 5 | g9569.t10 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 49 | 246 | 1.05E-46 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0036402 | proteasome-activating activity | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
