General information for g9601.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as histone-arginine N-methyltransferase.
Parent gene
- The parent gene g9601 is located on chr_1: 4240562..4241130 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9601 | g9601.t1 | TTS | g9601.t1 | 4233779 | 4233779 |
| chr_1 | g9601 | g9601.t1 | isoform | g9601.t1 | 4234369 | 4240562 |
| chr_1 | g9601 | g9601.t1 | exon | g9601.t1.exon1 | 4234369 | 4234667 |
| chr_1 | g9601 | g9601.t1 | cds | g9601.t1.CDS1 | 4234369 | 4234667 |
| chr_1 | g9601 | g9601.t1 | exon | g9601.t1.exon2 | 4236065 | 4236238 |
| chr_1 | g9601 | g9601.t1 | cds | g9601.t1.CDS2 | 4236065 | 4236238 |
| chr_1 | g9601 | g9601.t1 | exon | g9601.t1.exon3 | 4236300 | 4239389 |
| chr_1 | g9601 | g9601.t1 | cds | g9601.t1.CDS3 | 4236300 | 4239389 |
| chr_1 | g9601 | g9601.t1 | exon | g9601.t1.exon4 | 4239462 | 4239556 |
| chr_1 | g9601 | g9601.t1 | cds | g9601.t1.CDS4 | 4239462 | 4239556 |
| chr_1 | g9601 | g9601.t1 | exon | g9601.t1.exon5 | 4239622 | 4240562 |
| chr_1 | g9601 | g9601.t1 | cds | g9601.t1.CDS5 | 4239622 | 4240562 |
| chr_1 | g9601 | g9601.t1 | TSS | g9601.t1 | 4241138 | 4241138 |
Sequences
>g9601.t1 Gene=g9601 Length=4599
ATGGCTTTTCACAATCCGGAAATATTTAAAGATTTAAAATTACACTCTCCATCAGACGCT
GAGCCATTTGTATACAAATGGCCTCTATCAGTCGGAATAGGACCAGATAAGCATGACAGT
GGTCTTGAAATAATTGAAACGGTTCGATTGGTATGTGAAGACATTCCTGAAATAAAATCA
TCATTAGAGGACATTTCATTAACCGAACTGGATACAAATGACTATGATACAATGAAAAAT
TTCTGTGACCGTTTTAATAAGGCTATTGATAGTATTAAATCTCTTGAGAAAGGCACTTCA
CTGCCCGTTAGACGACATACACTGCCCTCGAGAAATATGCTAAGACATATTGTTCAACAA
GTCTATAATTACGCTGTTTCAGAGCCAGAGAAGCTTAATCAATACGAGCCATTCTCACCA
GAAGTCTATGGTGAAACCAGTTTCGATTTCATTAGTCAAATGGTCGACGAAATAAATATA
ACGGAAGATGATGTTTTTATTGATCTTGGCAGTGGCGTGGGACAAGTAGTTTTGCAAGTT
GCCGCGTCTACTCGATGCAAAATTTGCATTGGCATTGAAAAAGCAGATGTTCCATCTAAA
TATGCTGAAAATATGAATGGAATGTTTAAAACTTGGATGCGATGGTTTGGAAAAAAATAT
GGTGACTATCAGTTGATTAAAGGTGATTTTTTAGCTGATGAACATCGCGAAAAAATAATG
TCTGCCTCAGTGGTATTTGTAAATAATTTCGCTTTTGGCCCAAACGTTGATCATCAATTG
AAAGAAAGATTTGCAGACTTGAAAGATGGCGCAAAAATTGTTTCATCCAAAAGTTTTTGT
CCATTGAATTTTCGTATCACTGATCGAAATCTTAGTGATATTGGAACGATAATGCATGTA
AAAGAAATGGCACCACTTAAGGGATCTGTTTCATGGACTGGTAAACCCGTTTCATATTAT
CTTCACACCATCGATCGAACGAAACTTGAGAATTACTTTCAAGGTCTTAAAACAAAGGGC
AATGGAAACGGAGACGGTAATGGCAAAAATCGTCGAAGTCGTGATTACAATAAGCAAACG
AGTGGTTCAACGTCAGAAAGTGATGATGATGATGCTGATTATACGGGAACGACAACGCGA
AAAGCTTGGTCTGACTTTGTGAAAGCAAGAAGCAGTCAATCTGAAGATGAGTCTATTAAT
GATAAAAAGAAGAAGCCACAACTAGCAAAAGCAAGAAGAGTGCCTGCACAGAAGAAAGTA
GCAAAGGCGAATGCAGCTGGTGGTAGAGTGAAAAAGCCAAAACATAAACGTCAACTGAAA
ATTGCTGGACTTGATTTATTACATTCTCAAACAATTTTCAGTACTTCAGATCAAGCTATT
GGAATTCGAATGCCACCAGCCGCTGGTTGCGTTGATGAACGTTTAACAAATTATGCTGGC
ACAATGATTCATGAGGAAGTCGATGAGCCATTAGTTCATAATTCGTCTGAAGTTCCATAT
GGACTTAAAATTCTTTTGGATGTTTATAAGACTCAATTTATGAATTTCTTAGAATCAATG
AAATCGTCAGCATTTAAAGAAAATCTACATCGACAAATTGAAAGCGAAAAAGAGAAAAAT
AAACGTTTATTGAACCGTACTGGACAGCTTGAAAAGCAAATAAAAGTTCTTGTTGAAGAC
AGTGTTGTGTTATTGAAGGCGAGAATGCAAGAACTTGGTATCAATACGAGCAGTCAAAAT
GATTTGCTTTGCAAGGCCAAAGAAATTGTTGGAAAACACAAAGAATTACAAATCATGGCC
AATAAAATTCAAGCACAAGTGAATACATTAGAAGAAGAGCATAATAATATTCTGGCAGGT
CACGTGAAGAAAATTGCAGAGAAACATTCAAAACAGTCAATGGATTTTGAATTGGCATCG
AAAGACTCACATGACTTGGTGCTTAAAGAAATCGAAAATACTTTTATTCAACGTAAAAAT
TTACGAAATAAAATTTCATCATTAGAGGCTGAATTGGCATTGATTGAGAAAGCGAGTGAA
GAGCGAAAGCAAACGTCAAATACTGGCAATAGTGCTCAGTCTAATATTTATGTTTCTGGA
AATATTTATAAGCAATCTAATAATCCTCCATCTAATGTTACAAATGCTACTGCACAGCAA
TCATCAACGTCTAAAACTTCAAAGAAAAATCGTGAGCATCGACCTAAAACTCATGAATGG
CCAGAAATACCAGACATTGGAAAAATTGAAGAAAAGAATCCAGAAATTCTAGCACAGAAA
ATACTCGAAACTGGTCGTCAGATTGAAGCAGGAAAGTTCCAAACTACAACAGTAAGTGCA
TCAAATCTTCCACCGAGCAAAATTGCAAAATCAGAAAGTGTGCAGCAGCCTTATACCAAA
AAACATCCTACAAGCGTTCCTCAGCAACTACCGCAAACACAACCGCAGCATCATTTACCA
CAGCATGCGATTATGTCAAATAAAAATGAGATAATGCAAATGACAGTCCATAAAGTGGGT
GGTAAGCCGCAGGCACATCAGGGTCATATTTCTTTACTACCAAAAGCCGGTGGCTCATCC
AAAAAAGTCGCAGAATCACATAAAGTTGTGAATTTCGAAGATAGATTAAAGAGTATTATC
ACTTCAGCATTGCAAGGTCAAGATCAAGCTGGTCAAAATCAAAAACAAAATTTACCACCA
CAACAATCATCTCAACAATCTCTTCCATCTCATATTACTCCGCAAACAAATGTCAGTCCG
AAGAAAATTCCACAAAGTCAAGCTGGACCTTACCATCATTCAGCTTATATTAGCTCAGCA
CATCCACAAGTTTCTCAACAAACAACATCACCTCAAATGTTGACAATAAGTACAAGTAGT
GGTCAACCGCAATCTCATCATCATTTGTCAACAATTTCACCTACACAATCATCGCCCATA
AAGAATCAGAGACAAATGGTTCCACTTCCACAAATGGCACCACATTTACCACCCGAGCAT
TCACGTGAATTGCAAATGCAAGAATCGACATATGCTCAACTTAAAAGAAATGACCATATG
CCAAATTTTGCTAAAGTCATGAATATTATGCATCATGATACTAGTAAAATGTATCAACGA
CATCCTCAAATGTCAATGATGCAGCAACATCAGCAAGGACAATTTGCAATGCAACGAGAG
CGAGAGCGTGAAGGTGCAATGATGTATCAACAGCGACAAATTGTTGAAGAGAAGCGTGAG
TTCAAAACTCCCGATAATGTGAGATGCCAAGATATGGGACGAAGCTCAGTGGGATCGATT
GAGAACGAGTACATAAATAGTGGTAGTAATAGTAGTAGCAATAAATCTCAAACACAACGA
TCAAGTTCTTCTTTATCACAACCAGATTATACTCAAGTATCACCAGCAAAACTTGCACTA
AGACGACATTTGTCACAAGAGAAGCTGGCACAACATCAAGTGGGACCATCACAATTGACC
ACAAAAACAATTGGTGATTTTATCAATAGTGAAATTGAAAAGACACTTGAAATAACACCG
CAATCGATTATAAATGCAGTCATTCAACATAATATGCCAAGTAGTTCACGAATAAATAAT
GAATCAATAATTGACTGTAGTATAAATCAGGATCGTGAACTTGATGACCATCATCATCCA
TATGCTACTCTAAAACCAACGCCTAGTAAGCAGCAGCAGCAACAACCAGGACCATATATG
CATGATCCTTATATAGATCATCATCGTACAAAAATGTTACCAGTTCAATCGAAATATGTT
TCACCAACATCTGCCAATGCGAGAAAAAGTGCAATATCTACGCCACCATTGCGACATGAT
GAAGCTATGAATTATATGAATGCTTCAAAATCACCAGAACGTTATCAAGAGTCGAGTTAC
AAGATAGACACAAAAATGTTCACATCATCTAATATTGGAATGTCAATGCGAAAGGAAGAA
GTTAAAGAGAAAATGTCAGTTGAACATGAACCTCCACTCGAAGGACTTGCAGCATCTTTG
CGACAACATGTTATTGCTTCGATGAAAATTAAGGAGGAATCCGAGAATGAACCAAAATAT
TCAAATTATCATCCAACAATACCATACCCTCACATCAAAAAAGAATCCACAAACCGTATG
AAACGAGCATCGCCAGTTATTCTTCAACGTCAACAGGGAGGAAATAGTGGTCCAATGTAC
AATGAAATGAATGAGGAAATGATGTATATGGGACCATCATCTTCAAGTAATAACGAAAGA
AATTTGACTCCTTTAAGTCATCTTCGTCGCACCGATGAAGATGATATGGGCGATGATGAT
GACATACAATGGCCAGAGGACTTTAAAGTACGAGTATCATCAGGCTTTGATCGTTTAGTT
GCATTTGCTGCTACTGAGCTGAATCGTCGTTCTGATGAAAATTGTGTCAGTCCACCGAAA
CGTGAAATGTCCTACGTTGATTATAGATCTTCCCATATGAAGAAAGAAGATACAAGAAAA
ATGAAAAACGAACGCGATTATCCTGCCGATCTTAGTGAAAGACGTATGCGAATGATGATT
GAAGAGAATCGAAAAAGTAGCAAACATCATTTGGATTAG
>g9601.t1 Gene=g9601 Length=1532
MAFHNPEIFKDLKLHSPSDAEPFVYKWPLSVGIGPDKHDSGLEIIETVRLVCEDIPEIKS
SLEDISLTELDTNDYDTMKNFCDRFNKAIDSIKSLEKGTSLPVRRHTLPSRNMLRHIVQQ
VYNYAVSEPEKLNQYEPFSPEVYGETSFDFISQMVDEINITEDDVFIDLGSGVGQVVLQV
AASTRCKICIGIEKADVPSKYAENMNGMFKTWMRWFGKKYGDYQLIKGDFLADEHREKIM
SASVVFVNNFAFGPNVDHQLKERFADLKDGAKIVSSKSFCPLNFRITDRNLSDIGTIMHV
KEMAPLKGSVSWTGKPVSYYLHTIDRTKLENYFQGLKTKGNGNGDGNGKNRRSRDYNKQT
SGSTSESDDDDADYTGTTTRKAWSDFVKARSSQSEDESINDKKKKPQLAKARRVPAQKKV
AKANAAGGRVKKPKHKRQLKIAGLDLLHSQTIFSTSDQAIGIRMPPAAGCVDERLTNYAG
TMIHEEVDEPLVHNSSEVPYGLKILLDVYKTQFMNFLESMKSSAFKENLHRQIESEKEKN
KRLLNRTGQLEKQIKVLVEDSVVLLKARMQELGINTSSQNDLLCKAKEIVGKHKELQIMA
NKIQAQVNTLEEEHNNILAGHVKKIAEKHSKQSMDFELASKDSHDLVLKEIENTFIQRKN
LRNKISSLEAELALIEKASEERKQTSNTGNSAQSNIYVSGNIYKQSNNPPSNVTNATAQQ
SSTSKTSKKNREHRPKTHEWPEIPDIGKIEEKNPEILAQKILETGRQIEAGKFQTTTVSA
SNLPPSKIAKSESVQQPYTKKHPTSVPQQLPQTQPQHHLPQHAIMSNKNEIMQMTVHKVG
GKPQAHQGHISLLPKAGGSSKKVAESHKVVNFEDRLKSIITSALQGQDQAGQNQKQNLPP
QQSSQQSLPSHITPQTNVSPKKIPQSQAGPYHHSAYISSAHPQVSQQTTSPQMLTISTSS
GQPQSHHHLSTISPTQSSPIKNQRQMVPLPQMAPHLPPEHSRELQMQESTYAQLKRNDHM
PNFAKVMNIMHHDTSKMYQRHPQMSMMQQHQQGQFAMQREREREGAMMYQQRQIVEEKRE
FKTPDNVRCQDMGRSSVGSIENEYINSGSNSSSNKSQTQRSSSSLSQPDYTQVSPAKLAL
RRHLSQEKLAQHQVGPSQLTTKTIGDFINSEIEKTLEITPQSIINAVIQHNMPSSSRINN
ESIIDCSINQDRELDDHHHPYATLKPTPSKQQQQQPGPYMHDPYIDHHRTKMLPVQSKYV
SPTSANARKSAISTPPLRHDEAMNYMNASKSPERYQESSYKIDTKMFTSSNIGMSMRKEE
VKEKMSVEHEPPLEGLAASLRQHVIASMKIKEESENEPKYSNYHPTIPYPHIKKESTNRM
KRASPVILQRQQGGNSGPMYNEMNEEMMYMGPSSSSNNERNLTPLSHLRRTDEDDMGDDD
DIQWPEDFKVRVSSGFDRLVAFAATELNRRSDENCVSPPKREMSYVDYRSSHMKKEDTRK
MKNERDYPADLSERRMRMMIEENRKSSKHHLD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g9601.t1 | CDD | cd02440 | AdoMet_MTases | 166 | 274 | 0.00102162 |
| 8 | g9601.t1 | Coils | Coil | Coil | 526 | 553 | - |
| 7 | g9601.t1 | Coils | Coil | Coil | 593 | 613 | - |
| 9 | g9601.t1 | Coils | Coil | Coil | 651 | 688 | - |
| 5 | g9601.t1 | Gene3D | G3DSA:1.10.260.60 | - | 10 | 131 | 1.5E-44 |
| 6 | g9601.t1 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 132 | 350 | 4.9E-82 |
| 11 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 338 | 375 | - |
| 18 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 389 | 433 | - |
| 13 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 390 | 405 | - |
| 14 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 710 | 739 | - |
| 21 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 710 | 725 | - |
| 17 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 776 | 803 | - |
| 16 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 885 | 980 | - |
| 20 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 885 | 924 | - |
| 19 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 938 | 980 | - |
| 22 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1075 | 1134 | - |
| 12 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1089 | 1133 | - |
| 15 | g9601.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1491 | 1512 | - |
| 2 | g9601.t1 | PANTHER | PTHR21451 | HISTONE H3 METHYLTRANSFERASE | 33 | 600 | 2.3E-190 |
| 3 | g9601.t1 | PANTHER | PTHR21451:SF0 | HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC | 33 | 600 | 2.3E-190 |
| 1 | g9601.t1 | Pfam | PF08123 | Histone methylation protein DOT1 | 122 | 324 | 9.8E-82 |
| 23 | g9601.t1 | ProSiteProfiles | PS51569 | Histone-lysine N-methyltransferase DOT1 (EC 2.1.1.43) domain profile. | 21 | 337 | 93.297 |
| 4 | g9601.t1 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 14 | 334 | 6.4E-75 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051726 | regulation of cell cycle | BP |
| GO:0034729 | histone H3-K79 methylation | BP |
| GO:0031151 | histone methyltransferase activity (H3-K79 specific) | MF |
| GO:0018024 | histone-lysine N-methyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K11427 ([histone H3]-lysine79 N-trimethyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
