General information for g9748.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aminopeptidase N.
Parent gene
- The parent gene g9748 is located on chr_1: 4981837..4984638 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9748 | g9748.t1 | isoform | g9748.t1 | 4981837 | 4984638 |
| chr_1 | g9748 | g9748.t1 | exon | g9748.t1.exon1 | 4981837 | 4982062 |
| chr_1 | g9748 | g9748.t1 | cds | g9748.t1.CDS1 | 4981837 | 4982062 |
| chr_1 | g9748 | g9748.t1 | exon | g9748.t1.exon2 | 4982126 | 4984638 |
| chr_1 | g9748 | g9748.t1 | cds | g9748.t1.CDS2 | 4982126 | 4984638 |
| chr_1 | g9748 | g9748.t1 | TSS | g9748.t1 | 4984663 | 4984663 |
| chr_1 | g9748 | g9748.t1 | TTS | g9748.t1 | NA | NA |
Sequences
>g9748.t1 Gene=g9748 Length=2739
ATGCGGTTATTTGTCAAAGTGTTAAGTTTTTTGTTAGTGATAATATTTTTTAGTGTGCAT
GGATTGCATAATAATTCCACAGAAATTTCTATAGAACCTTTAACTTATAGATTACCAAAT
GACTCTTTACCTTTGAGTTATGATTTAACAATAAAAACTGAAATTCATCGCAAAAATTTG
AACTTTGTTGGAAATGTAAAAATTCATGTACAAATTCAGAATAGAACTAAAAAATTAACA
CTTCATTATCATGGAATTGTGATTGATTTTGTGGATTTATTGACAGTGAACAGAAATGAA
ATGATTGCAAGGAATTTAACTTTGCATAAGCTTCCAAAATTTGATTTTTTAATTATTTTG
CTGCCAAGAGAATTTAATCCAAATGAAGAATTTATTCTCAATATTTCTTATCATGGAAAA
TTAACTAAATCAAAACTTGGATTTTTTTATTCTTCATATTTGGATTACAATAATACAGAA
ATTTATTATGCTGCAACACAATTTGAAACAATTTATGCTCGTCGTGCACTACCTTGCTAT
GATGAGCCAGCAAAAAAGGCTAAAATTACTTTGTCAATAATTCATGGAAAAGATTATCGT
GCTGTTGCAAACACAGAAATGATAAGTTCATTGCCATTTGATGAAAATCAAGATTATTTG
ATTACAAAATTCAACACAACACCTTCAATTCAAACTTATTTGCTTGCTTTTTCAATTTCT
AACTTTCAATACATAAATGGCTTGAATTCAAGAATTTCACAAAAAATTTATGCAAATCCA
ATTGATATTGCAGAAGGAAAATTAAATTTTGCTGCATCTGTTGTTGGTCCAATATTAAAA
GGTATTGAAAGTCTTTTAGGAATTGAATATCCTTACAATAAACTGGATCATCTAAGCTTA
GATCTTGAATACTTCGGTGCAATGGAAAATATTGGACTACAAATTTACGATATTAATGAA
ATAAATTTCAAAGTTCATTCTTATGATAAAGCAAGAACAAATAAACAAAAATTAAAAGTC
ATTCGAACAATTGCACATGAAACTTCTCATCAATTTTTTGGTGATTTAACAACACCAGCT
TGGTGGAATTATGCATTTTTGAATGAAGGATTTGCAACACTTTTTGAGTCACTTATTCCA
AGCATTATTTTTCCTCAATATCATCAAATGTCGCATTTTTTTATCAAAAATTTCCCTGAT
GCCTTTGCTAGAGACACAAAAGAATTAAATTCATGGTCTATGAATAAATATACTGAAAAT
CCAAATGAATTATGGACAAAATTTAATCGAATTGGTTATCAAAAATCAGGTTGTGTTTTA
AGAATGTTTATGGAAGTTATGACACAAAAAACTTTCATTAAAGGACTAAAATTTTACTTA
AATGAAATGTATTGGAAAACTGCAACTCCTGATGATTTGCATAGAAATTTACAAGTCGCT
TTTGATCAAGATTTTCCAACTGTAATTTTAAACATCAGTGAATTGATGTCAACTTGGGAA
AATCAAGCTGGCTATCCATTAGTGACAGTCACTATCTCAGGAAGTAACTTAAAATTTTCA
CAAAAAAGATACCCATCAGGAAATGAAGAAATTTATTCAGTTCCACTCACAATTGCTACA
AAAACAAATCCAAATTTCAATCATACAACTCCAAAACAATGGCTTTTAACTCAAAATGCA
ACTTTCACTCAGTCAGAGTTAGAATTTAATGCCACAAACAATGATTGGATGATTTTGAAT
ATTCAACAAGTTGGTTATTATCGAGTTGACTATGACACTGCATTATGGCAAGCAATCATT
TCACAATTGAATGAAAATCATGAAGAAATTCATCCAATCAATCGTGCAATTTTACAGGAA
GAAATTGCTTTAGCTTGGACTGAATTTAATAGAGTTACAGCTTGTGATGTTTTAAACAGT
TTGAATTATTTTGATAAGGAAGACGAATTGCTTGCATGGAACAAAGCTGATAAAATTTTT
GATGAATTTTACACAAAACTTTTTACAACTGAACAATTTCCAAATTATTTGGAATTTTTG
AACGCTTTAACATCACCGATAATGAAAAATCTTGGTTTTGATGATCTCAGTGATGAAGAT
GTTCATATTACAGATTTAAGGGATATTGTAAAGAGATGGAATTGCAAAGCTCTCAATAGT
GATTGCTTAAACCATGAAAAATTAAAATTTGAATATTTTTATCAATTGAATAAATTTGAC
AGTCTAATTGATGTCTGTTCAGCAAGGAGAAATATTAAAAATATGGATAAAATTATTAAA
GAAATTGTCAACAATAAAACAGTCATAGATCGTAGTGAAGCTTTTAGAAACCTTGGTTGT
GCACTTGATGAAAAGGAAATAAAAATTCTTTTGAATTCAATTAGGAAATATCCAGATGAA
ATAAGCACCAAAGAAATCTCAAATATAATTTGGCAAACTTTTGACAAAAGTCCAATCGCA
TTACAATCAGTTTTAGACTTTATCGAAGAAGACACTCATGAATTTTATAATTTATTTTCA
ACGTCAGCATTGTACAATTTTCTCACGTCTGTAGCCAAGTTGATTTATAATGAGCCAATA
ATGGAACAATTCAGAAGAATTTTGACTGTTTCATTTGATGATTTTACAACTTCAAAAAAC
TGTTATTTGTCAATTACTGGAATTCTTAATGATAATCAAAAATGGATGGACAAAAATTAT
AAAAATATTGAAAATTGGTTCAATAAAAGACAAAAATGA
>g9748.t1 Gene=g9748 Length=912
MRLFVKVLSFLLVIIFFSVHGLHNNSTEISIEPLTYRLPNDSLPLSYDLTIKTEIHRKNL
NFVGNVKIHVQIQNRTKKLTLHYHGIVIDFVDLLTVNRNEMIARNLTLHKLPKFDFLIIL
LPREFNPNEEFILNISYHGKLTKSKLGFFYSSYLDYNNTEIYYAATQFETIYARRALPCY
DEPAKKAKITLSIIHGKDYRAVANTEMISSLPFDENQDYLITKFNTTPSIQTYLLAFSIS
NFQYINGLNSRISQKIYANPIDIAEGKLNFAASVVGPILKGIESLLGIEYPYNKLDHLSL
DLEYFGAMENIGLQIYDINEINFKVHSYDKARTNKQKLKVIRTIAHETSHQFFGDLTTPA
WWNYAFLNEGFATLFESLIPSIIFPQYHQMSHFFIKNFPDAFARDTKELNSWSMNKYTEN
PNELWTKFNRIGYQKSGCVLRMFMEVMTQKTFIKGLKFYLNEMYWKTATPDDLHRNLQVA
FDQDFPTVILNISELMSTWENQAGYPLVTVTISGSNLKFSQKRYPSGNEEIYSVPLTIAT
KTNPNFNHTTPKQWLLTQNATFTQSELEFNATNNDWMILNIQQVGYYRVDYDTALWQAII
SQLNENHEEIHPINRAILQEEIALAWTEFNRVTACDVLNSLNYFDKEDELLAWNKADKIF
DEFYTKLFTTEQFPNYLEFLNALTSPIMKNLGFDDLSDEDVHITDLRDIVKRWNCKALNS
DCLNHEKLKFEYFYQLNKFDSLIDVCSARRNIKNMDKIIKEIVNNKTVIDRSEAFRNLGC
ALDEKEIKILLNSIRKYPDEISTKEISNIIWQTFDKSPIALQSVLDFIEEDTHEFYNLFS
TSALYNFLTSVAKLIYNEPIMEQFRRILTVSFDDFTTSKNCYLSITGILNDNQKWMDKNY
KNIENWFNKRQK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g9748.t1 | CDD | cd09601 | M1_APN-Q_like | 45 | 499 | 1.96076E-128 |
| 14 | g9748.t1 | Gene3D | G3DSA:2.60.40.1730 | tricorn interacting facor f3 domain | 32 | 242 | 6.6E-56 |
| 15 | g9748.t1 | Gene3D | G3DSA:1.10.390.60 | - | 246 | 504 | 5.0E-57 |
| 13 | g9748.t1 | Gene3D | G3DSA:2.60.40.1910 | - | 505 | 591 | 1.3E-18 |
| 16 | g9748.t1 | Gene3D | G3DSA:1.25.50.20 | - | 593 | 912 | 7.2E-35 |
| 4 | g9748.t1 | PANTHER | PTHR11533:SF283 | AMINOPEPTIDASE | 32 | 904 | 2.2E-166 |
| 5 | g9748.t1 | PANTHER | PTHR11533 | PROTEASE M1 ZINC METALLOPROTEASE | 32 | 904 | 2.2E-166 |
| 6 | g9748.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 174 | 189 | 3.7E-16 |
| 8 | g9748.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 224 | 239 | 3.7E-16 |
| 7 | g9748.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 343 | 358 | 3.7E-16 |
| 9 | g9748.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 362 | 374 | 3.7E-16 |
| 3 | g9748.t1 | Pfam | PF17900 | Peptidase M1 N-terminal domain | 44 | 234 | 1.1E-40 |
| 2 | g9748.t1 | Pfam | PF01433 | Peptidase family M1 domain | 271 | 499 | 4.1E-44 |
| 1 | g9748.t1 | Pfam | PF11838 | ERAP1-like C-terminal domain | 576 | 856 | 1.4E-25 |
| 18 | g9748.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 19 | g9748.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 20 | g9748.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 17 | - |
| 21 | g9748.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 18 | 21 | - |
| 17 | g9748.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 912 | - |
| 11 | g9748.t1 | SUPERFAMILY | SSF63737 | Leukotriene A4 hydrolase N-terminal domain | 32 | 240 | 2.22E-42 |
| 10 | g9748.t1 | SUPERFAMILY | SSF55486 | Metalloproteases (zincins), catalytic domain | 256 | 510 | 1.17E-50 |
| 12 | g9748.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008237 | metallopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
| GO:0008270 | zinc ion binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed