General information for g9750.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aminopeptidase N.
Parent gene
- The parent gene g9750 is located on chr_1: 4987710..4989329 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9750 | g9750.t1 | isoform | g9750.t1 | 4987710 | 4989329 |
| chr_1 | g9750 | g9750.t1 | exon | g9750.t1.exon1 | 4987710 | 4989329 |
| chr_1 | g9750 | g9750.t1 | cds | g9750.t1.CDS1 | 4987710 | 4989329 |
| chr_1 | g9750 | g9750.t1 | TSS | g9750.t1 | 4989355 | 4989355 |
| chr_1 | g9750 | g9750.t1 | TTS | g9750.t1 | NA | NA |
Sequences
>g9750.t1 Gene=g9750 Length=1620
ATGTGGTGGCTAAAAGCAATAGTGAGTGCTCTTGTGATAATAAATATTGGAAGTGGCAAT
CCAATATTAAATAATGAAGAATTACATAATATTGAAGAAAATAAGTTCAGAGAAGTTCCT
GCAATTAAACAAAAGACAAAACTGGTTGATGCAGAAGAATCTTATCGTCTTCCAAATACT
TCTATTCCATTAAGCTATGACATAACAATCAGAACTGATATTCATAATGCAATTTTTGAC
TTTTCTGGTTACGTAAAAATTCATGCAAAAATTTTAGAAGCAACTGAAGAAATTATCCTT
CATTATCGTCAAATTGAAATTGATTATATTGATTTATTCAATTCAACTGGAATTGTTGCT
TCAGATTTGAAATTTGAGAAAATTTCGAAGTTTGAATTTCTTAATATTACTTTGCCAAGA
ATTTACAATCCAGATGAAGAAATTATTCTTGAAATAGCTTATCATGGAGAAATTCGACGT
GATGGAGGTGGTTTTTATTATGGAAGCTATACAAATGAAGAAGGTCAAAATGTTTATTAT
GCAACAACACAATTTGAAGTAACTGATGCACGCCATGCTATGCCTTGCTATGATGAACCT
GGTATTCGTGCACCAATGACTTTGACAATCATTCATGGAAAAAAATACTCAGTTGTTGCA
AATATGAATATTGATAGTCAAGAAAATCAAGGAGGTTACACAGTCACAAAATTCAAACCA
ACACCATCAATTCAGACTTATCTTTTGGCATTCTTAATTTCTGATTTTGATTATGTTAGT
GCCACTAACAATTCAAGAATTTCACAAAAAATTTATGCAAAACCAGAAGCAATTAAAAAC
GGTGAAGGAGATTTTGCAGCTTCAGTTGTAGGTGATGTTCTAGCTAGACTTGAAGAAGTT
CTTAAATTTAATTATCCAAATGATAAAATGGATCATGCTGCATTGAATTATTTCAATTTT
GGTGCAATGGAAAATTTCGGTTTAATTACTTATATTGATAGAGGTTTGCTTTTAAATCCA
TCACTTACTGAAAATCAAAAATATATTAGCCAAAATTCGATTACTGGTTTAATTGCTCAT
GAATTTGCACATCAATGGTTTGGAAATATTATTTCACCAAAATGGTGGACTTACACTTGG
CTCAATGAAGGTTTTGCAACACTTTTTGCTTCTTATATTCCACATTTGATTTATCCTGAA
AGAAATATTTTTGCAAGAGGTTATATCAACAATATAAGAACTGCTTTTGCAAATGATGTC
AATAATTCATGGGCAATGAATCATTATACTGAACTTCCAAATGAATTATGGAGTAAATTT
GGTGCAATTGGATATCAAAAATCAGGATGTGTTTTAAGAATGTTTATGGAAGTTATGACA
CGTGAAGTTTTCTTCAATGGATTGAATTATTATTTGACAGCAAATAATATGCAAGCAGCA
ACACCAGCAGAGCTTCACGTAGGTTTACAAACTGCTTATGATCAAGCCAACTTTACAACA
CCATTAAATATTGATCAATTGATGTCAACTTGGGAAAATCAAGCTGGCTATCCATTGGTG
ACAGTCACTATCTCAGGAAATAACTTACAATTTTCACAAAAGAATACCCATCAGGAATGA
>g9750.t1 Gene=g9750 Length=539
MWWLKAIVSALVIINIGSGNPILNNEELHNIEENKFREVPAIKQKTKLVDAEESYRLPNT
SIPLSYDITIRTDIHNAIFDFSGYVKIHAKILEATEEIILHYRQIEIDYIDLFNSTGIVA
SDLKFEKISKFEFLNITLPRIYNPDEEIILEIAYHGEIRRDGGGFYYGSYTNEEGQNVYY
ATTQFEVTDARHAMPCYDEPGIRAPMTLTIIHGKKYSVVANMNIDSQENQGGYTVTKFKP
TPSIQTYLLAFLISDFDYVSATNNSRISQKIYAKPEAIKNGEGDFAASVVGDVLARLEEV
LKFNYPNDKMDHAALNYFNFGAMENFGLITYIDRGLLLNPSLTENQKYISQNSITGLIAH
EFAHQWFGNIISPKWWTYTWLNEGFATLFASYIPHLIYPERNIFARGYINNIRTAFANDV
NNSWAMNHYTELPNELWSKFGAIGYQKSGCVLRMFMEVMTREVFFNGLNYYLTANNMQAA
TPAELHVGLQTAYDQANFTTPLNIDQLMSTWENQAGYPLVTVTISGNNLQFSQKNTHQE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 20 | g9750.t1 | CDD | cd09601 | M1_APN-Q_like | 64 | 511 | 2.62914E-154 |
| 13 | g9750.t1 | Gene3D | G3DSA:2.60.40.1730 | tricorn interacting facor f3 domain | 44 | 256 | 8.2E-60 |
| 14 | g9750.t1 | Gene3D | G3DSA:1.10.390.60 | - | 257 | 516 | 1.6E-68 |
| 3 | g9750.t1 | PANTHER | PTHR11533:SF283 | AMINOPEPTIDASE | 48 | 535 | 1.6E-139 |
| 4 | g9750.t1 | PANTHER | PTHR11533 | PROTEASE M1 ZINC METALLOPROTEASE | 48 | 535 | 1.6E-139 |
| 8 | g9750.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 191 | 206 | 2.1E-24 |
| 7 | g9750.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 238 | 253 | 2.1E-24 |
| 5 | g9750.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 318 | 328 | 2.1E-24 |
| 9 | g9750.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 357 | 372 | 2.1E-24 |
| 6 | g9750.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 376 | 388 | 2.1E-24 |
| 2 | g9750.t1 | Pfam | PF17900 | Peptidase M1 N-terminal domain | 63 | 248 | 2.5E-41 |
| 1 | g9750.t1 | Pfam | PF01433 | Peptidase family M1 domain | 286 | 511 | 1.7E-50 |
| 16 | g9750.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 17 | g9750.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 5 | - |
| 18 | g9750.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 6 | 14 | - |
| 19 | g9750.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 15 | g9750.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 539 | - |
| 11 | g9750.t1 | SUPERFAMILY | SSF63737 | Leukotriene A4 hydrolase N-terminal domain | 50 | 255 | 2.88E-46 |
| 10 | g9750.t1 | SUPERFAMILY | SSF55486 | Metalloproteases (zincins), catalytic domain | 265 | 522 | 7.77E-59 |
| 12 | g9750.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008237 | metallopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
| GO:0008270 | zinc ion binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed