Gene loci information

Transcript annotation

  • This transcript has been annotated as Glutathione S-transferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g9863 g9863.t4 TTS g9863.t4 5747185 5747185
chr_1 g9863 g9863.t4 isoform g9863.t4 5747313 5747860
chr_1 g9863 g9863.t4 exon g9863.t4.exon1 5747313 5747623
chr_1 g9863 g9863.t4 cds g9863.t4.CDS1 5747313 5747623
chr_1 g9863 g9863.t4 exon g9863.t4.exon2 5747693 5747860
chr_1 g9863 g9863.t4 cds g9863.t4.CDS2 5747693 5747858
chr_1 g9863 g9863.t4 TSS g9863.t4 5748641 5748641

Sequences

>g9863.t4 Gene=g9863 Length=479
CCATGCCAATGATGCAGATGCCGGTTTTGGAAGTTGACGGCAAAAGAGCGCATCAGTCAC
TCGCTATGGCACGCTATCTTGCTAAACAAGTAGGATTGGTTGGATCAAATGATTGGGAAG
ATTTGGAAATCGATACTGTAGTTGATACAATTAATGATTTCCGCTTAAAGATTGCGGTCG
TTTCATATGAAGCAGACGAAGAAGTACAAAAGAAGAAGCGTGTTACGCTTGACAATGAGA
CAATTCCATTTTATCTCGAAAAACTCGACAGCATTGTTGCTGCTAATAATGGTCATTTTG
CATTGGGAAAATTAACTTGGGCTGATTTGTATTTCACTGCAATTCTTGATTATTTGAATT
ATATGGCAAAAACTGATTTAATTGCTAATCATGAGAATTTGAAGAAAGTTGTTGCAACAG
TTTTAGCTCTCGATGGAATCAAACAATGGGTTGAGAAGCGCCCACAAACTGATTTGTAA

>g9863.t4 Gene=g9863 Length=158
MPMMQMPVLEVDGKRAHQSLAMARYLAKQVGLVGSNDWEDLEIDTVVDTINDFRLKIAVV
SYEADEEVQKKKRVTLDNETIPFYLEKLDSIVAANNGHFALGKLTWADLYFTAILDYLNY
MAKTDLIANHENLKKVVATVLALDGIKQWVEKRPQTDL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g9863.t4 CDD cd03192 GST_C_Sigma_like 38 140 0.0000000
7 g9863.t4 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 35 0.0000000
6 g9863.t4 Gene3D G3DSA:1.20.1050.10 - 36 142 0.0000000
2 g9863.t4 PANTHER PTHR11571:SF234 GLUTATHIONE S-TRANSFERASE S1 1 158 0.0000000
3 g9863.t4 PANTHER PTHR11571 GLUTATHIONE S-TRANSFERASE 1 158 0.0000000
1 g9863.t4 Pfam PF14497 Glutathione S-transferase, C-terminal domain 51 153 0.0000000
9 g9863.t4 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 34 14.0330000
8 g9863.t4 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 36 158 19.1720000
11 g9863.t4 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 1 141 0.0000000
4 g9863.t4 SUPERFAMILY SSF52833 Thioredoxin-like 1 31 0.0000141
5 g9863.t4 SUPERFAMILY SSF47616 GST C-terminal domain-like 32 157 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values