General information for g9968.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase, mitochondrial.
Parent gene
- The parent gene g9968 is located on chr_1: 6293445..6300765 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g9968 | g9968.t7 | TSS | g9968.t7 | 6291027 | 6291027 |
| chr_1 | g9968 | g9968.t7 | isoform | g9968.t7 | 6291223 | 6293445 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon1 | 6291223 | 6291313 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon2 | 6291523 | 6291768 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon3 | 6291825 | 6291915 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon4 | 6291980 | 6292053 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon5 | 6292111 | 6292186 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon6 | 6292241 | 6292325 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon7 | 6292454 | 6292616 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon8 | 6292695 | 6292720 |
| chr_1 | g9968 | g9968.t7 | exon | g9968.t7.exon9 | 6292780 | 6293445 |
| chr_1 | g9968 | g9968.t7 | cds | g9968.t7.CDS1 | 6292789 | 6293445 |
| chr_1 | g9968 | g9968.t7 | TTS | g9968.t7 | 6293623 | 6293623 |
Sequences
>g9968.t7 Gene=g9968 Length=1518
ATGTTAAGAACAACAGTTCGTTCATTTATTAAAATTCATCAAAGATTTTATTCAATTCCT
GCAGCTCAAACGAATCCAGAGATACTTTATAATTTTCATAAATAATGAATGGCATAAATC
GGAATCGGGCAAGACTTTTAAAACAATTGATCCAACAACTGAAAATGTTATTGCTGAAAT
TCAAGAATCATCAAAAGTTGATGTTGATAAGGCAGTAGCTGCTGCAAAGAGTGCTTTTAA
ATTGGGTTCACCATGGAGACGTATGGATGCTAGTGAACGAGGTAATTTGCTTTTTAAACT
TGCTGACTTGATGGAGAGAGATCGCGTTTATCTTGCTAGTTTAGAAACTCTTGATAATGG
CAAACCTTATGCAATGAGTTACAATGTTGACCTACCAATGGCAATCAAAAATCTTCGTTA
TTATGCCGGTTGGGCAGATAAGAACCATGGAAAAGTTATTCCAATGGATGGAGAGTTCTT
TGCTTATACTCGACATGAACCAGTTGGTGTATGTGGGCAGATTATACCATGGAATTTTCC
TATTTTGATGGCTGCATGGAAATTGGGACCAGCACTCGCTACCGGAAACACTATCGTTTT
GAAACCGGCTGAACAAACACCACTTACTGCTTTATACATTGCTCAATTGAGTCGTGAAGC
AGGTTTAAATATTTATTAGTCGTTCCGGGTTTCGGTGAAACTGGACAACATTTAGTAAAT
CATAATGATATTGATAAGATTGCTTTTACTGGTAGTACAGAAGTTGGAAAATTAATCAAG
GCTGGTGCAGCAAACACACTGAAGAGAACAACACTCGAACTTGGAGGCAAATCACCAAAT
ATTATTTTATCGGATGCCGATATGAGTCATGCTGTAGAGACTTCACATTTTGGTCTTTTC
TTCAACATGGGTCAATGTTGTTGTGCAGGTTCAAGAACATTTGTAGAAGACAAGATTTAT
GATGAGTTTGTTGAGAGATCAGCAGAACGTGCAAAACGTAGAACTTTTGGAAATCCATTT
GACTTATCAACTGAACAAGGTCCACAAATCGATGCAATTCAACAAAATAAAATTCTTGGT
CTAATTGAAACAGGCAAAAAACAAGGAGCAAAACTTGTCGCTGGAGGAAATCCTGTAAAT
ATGAAAGGATATTTTGTTGAGCCAACTGTTTTTGCTGATGTAAAAGACGATATGACAATC
GCAAGAGAAGAAATTTTCGGACCTGTTCAACAAATTATTCGTTTTAAGAAGCTTGATGAA
GTGATTGAAAGAGCCAACAATACAGATTATGGTCTTGCAGCTGCAGTCTTTTCAAAAGAT
CTTGACAAAGTCAATTATCTTATTCAAGGCATTCGTGCAGGTACAGTCTGGGTGAATACT
TATAATATTTTAGGAGCGCAAGTTCCATTCGGTGGATTTAAAATGAGCGGACATGGTCGA
GAAAATGCGGAATATGGATTGCAGAATTATACAGAAGTCAAGAGCGTTATCATGCGCATA
CCACAGAAAAATTCATAA
>g9968.t7 Gene=g9968 Length=218
MSHAVETSHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKRRTFGNPFDLSTEQG
PQIDAIQQNKILGLIETGKKQGAKLVAGGNPVNMKGYFVEPTVFADVKDDMTIAREEIFG
PVQQIIRFKKLDEVIERANNTDYGLAAAVFSKDLDKVNYLIQGIRAGTVWVNTYNILGAQ
VPFGGFKMSGHGRENAEYGLQNYTEVKSVIMRIPQKNS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g9968.t7 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 2 | 180 | 2.9E-84 |
| 6 | g9968.t7 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 181 | 209 | 2.9E-84 |
| 2 | g9968.t7 | PANTHER | PTHR11699:SF233 | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL | 1 | 218 | 2.9E-107 |
| 3 | g9968.t7 | PANTHER | PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | 1 | 218 | 2.9E-107 |
| 1 | g9968.t7 | Pfam | PF00171 | Aldehyde dehydrogenase family | 2 | 209 | 5.6E-78 |
| 5 | g9968.t7 | ProSitePatterns | PS00070 | Aldehyde dehydrogenases cysteine active site. | 13 | 24 | - |
| 4 | g9968.t7 | SUPERFAMILY | SSF53720 | ALDH-like | 3 | 213 | 2.88E-74 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed