General information for g997.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Bromodomain-containing protein 8.
Parent gene
- The parent gene g997 is located on chr_3: 7379580..7382316 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g997 | g997.t1 | TTS | g997.t1 | 7379420 | 7379420 |
| chr_3 | g997 | g997.t1 | isoform | g997.t1 | 7379580 | 7382316 |
| chr_3 | g997 | g997.t1 | exon | g997.t1.exon1 | 7379580 | 7381126 |
| chr_3 | g997 | g997.t1 | cds | g997.t1.CDS1 | 7379580 | 7381126 |
| chr_3 | g997 | g997.t1 | exon | g997.t1.exon2 | 7381190 | 7381934 |
| chr_3 | g997 | g997.t1 | cds | g997.t1.CDS2 | 7381190 | 7381934 |
| chr_3 | g997 | g997.t1 | exon | g997.t1.exon3 | 7381995 | 7382205 |
| chr_3 | g997 | g997.t1 | cds | g997.t1.CDS3 | 7381995 | 7382205 |
| chr_3 | g997 | g997.t1 | exon | g997.t1.exon4 | 7382267 | 7382316 |
| chr_3 | g997 | g997.t1 | cds | g997.t1.CDS4 | 7382267 | 7382316 |
| chr_3 | g997 | g997.t1 | TSS | g997.t1 | 7382461 | 7382461 |
Sequences
>g997.t1 Gene=g997 Length=2553
ATGTCGACAAAAGAGCAGAAAATAAAGGAATTTTTACAAACAAAAAGAGCACCTCTGGAT
GAATGGAATACACATGAACAACTTTGCTTAGCGTCTGCTGTAGCTTGCAGTGGTGATCAA
AATTGGATGAGTGTGTCCAGAGCACTAAAAGGAATTGTTTTCTCTTACAATTCTCGTCCA
CAAGATTGGTTTTTATCAAAAAGTTGTGCTACGCAATATGGAAAATTATTGGAAAGTGTT
GAAACACCGAAAAGAAAGAAGAGAACTGCATCAGAAAGAGATGGATCTTCAACAGAACAA
CCTTCGACTCCAGTTGAATCTTTAGTAAAGAAACTTACAGCAGAACGAATAATTGAGCTG
AAAAAGGCCATTCTTGAAGAGCAACAAATGTATGCAAAATTGAAGGAAGAAATTCAATTT
TTACAGAGTTCATCAATGGATGAGACAAGAATTCGAGAAATGTGGCATCAAATTGAACAA
GAAAACATACAAAAAGAATGCGAAAAAGTTAAACATGATCAGTGGTTAAAAGAGCGAGAA
GAGAAGAAACTTGAGCACGAAAACAAATGGCGTGGCCCTAAAGTAAATATTCGTCCACAA
AAATCTATTGAAGAAATTGAGCCAGATACGACTACACAACAAGCAGGTACTTCGCCTCTA
CTCACTTCGCTTCTTAAATCACCATCACAAGCCCCAACATCAAATGTTCAGCAATCGATA
GTCTCGAGTAGCAGCAGTAATTCGAATTCCGTTCGCGCCCCTACCATCACAAATCTCCTT
ACCGGTTCATCATCACAAACATCATCTTCATCACAATCATCTTTGGCTTCCAATACTCCT
CTCATAACGCAAAATCCATCTGCACCAAACATTCTCATAAATGCTTCCTCTTCCACCAAT
ATGGTGCCAAATGTTATTAATTCTGCTTCTGTTTCCTCTGTAGTTACACATTCACATTCA
GCCCCAACTCTTATTGATTTACTTGATAAAAAATCATCACTCGCAGTTCCAGAACCGAGT
AGCAGCGGTGCTGGCAAAGAAGGAGATATTGTAAAAGATGAAGAAGCTGAACTATTGGCT
GACTTTAATGAAATCATTGATTGCGAGAAATTCGATATTGATGAAGATCTTGAGGACTTA
AACTCAATTATCATGAATCCAGAAATTCTTGATGAAAAAATTTCCGATGGTGAGCCTATA
AAAGATGCAGATGATTCTTCACAAGCGACATCAACAGATGATTATGATAAATTAAAAATT
AAACAAATTGTTGATTCGATTCAAGATATTGCTGGTGAATCAGAAGTTCCTACTACTACA
ACAACAACAGCAACTGCTATAATTATTCCAGAAGAAACACAAGATAAAATTATACCATCA
GTTGAAGAGACTGAAGTAGTTCAAATTCCATCTGAGGCAGAAAATTCAGCACCGACATCT
GTTGAAATGATTGAAGCTCCTATTGAGTCAAATGATTCGATTATTTTACAGACAAAAAAT
GAATCACCTCTACCAGAGAGTACTAAAATTGTCATGATTTCAGATGAAAGCTCAAATACA
AATGATAATGATCAGAAAAAGGAAGAAATGAGTGATAAAGTTGATACAAATGATGGAGAT
GAATCGCAAAGTATGAAATCTGATGAAATTAAAGATCCAAGTGGAGAAGATTCAAATAAA
GAAACGCAAGCAACATTCCAAGGAATTCCAATTGGTGAAAGTGATGAAAATTCAGTAAGT
AGTGAAAAGGAACAGAAAGAGACAACTGTTGCATATCCATTAGACGACTCAGATGATGCA
ATTTTTGAAGATGCAAGAGAACACCATTCAACAACTGAAAAATTACACGAATCAGATGTT
GTTGTTAAAGAACAATCACCTGAAAAATCTCTATCTGAAGCACCTGAATCGAAAACACCA
AAAACAGTTGTTGTAACCGAAAGTGAAGAAGCTTCACGCAGTGCTATCGATAGTGATGAT
GAGGTGGAAACAAAAACTTCAAGATCAACAAGTCGCAAAAAGGCAACTGATACACTAAAG
GCAGATACACCAAGCAGCTCTACTCGATCACGAGATCATTCAGAGAACGATGACAAAAGT
GATTCAACTCCGAGAACTAGAAGTCGTCATTCGTCAACTGCTGTTAGTGAATCTAAATCG
ACACAACTTTTTTCAAAAGAACAAGATCACAATATGTGGAAATCAAGATGGGAAGATTGT
GCTAGAGAACTGCAGAAATTAAAAGATTTTTCACAAATTGTAGACAACAAAGTCATTCAA
GATGATTATTATAAGAAAATTTGTCTGCATCCAATGAATTTGAAAATAATTGCTAAAAAT
ATTGAAAATCATATTTCAACACTAAAAAGTGACGTTGATCGCGATTTTGTTTTAATGTGT
ACAAATATCATGATGATAAATAACAAAGGACAGAAATTTGATGAAATTGTACAACAATTT
ATGAGAGATGGCAGAGAAATTATAGATTCTCATATGAGAGTTGATGATGCCTATAAAAGC
TATCGAAAACAAATAAAGAAACAAGTTCTTTGA
>g997.t1 Gene=g997 Length=850
MSTKEQKIKEFLQTKRAPLDEWNTHEQLCLASAVACSGDQNWMSVSRALKGIVFSYNSRP
QDWFLSKSCATQYGKLLESVETPKRKKRTASERDGSSTEQPSTPVESLVKKLTAERIIEL
KKAILEEQQMYAKLKEEIQFLQSSSMDETRIREMWHQIEQENIQKECEKVKHDQWLKERE
EKKLEHENKWRGPKVNIRPQKSIEEIEPDTTTQQAGTSPLLTSLLKSPSQAPTSNVQQSI
VSSSSSNSNSVRAPTITNLLTGSSSQTSSSSQSSLASNTPLITQNPSAPNILINASSSTN
MVPNVINSASVSSVVTHSHSAPTLIDLLDKKSSLAVPEPSSSGAGKEGDIVKDEEAELLA
DFNEIIDCEKFDIDEDLEDLNSIIMNPEILDEKISDGEPIKDADDSSQATSTDDYDKLKI
KQIVDSIQDIAGESEVPTTTTTTATAIIIPEETQDKIIPSVEETEVVQIPSEAENSAPTS
VEMIEAPIESNDSIILQTKNESPLPESTKIVMISDESSNTNDNDQKKEEMSDKVDTNDGD
ESQSMKSDEIKDPSGEDSNKETQATFQGIPIGESDENSVSSEKEQKETTVAYPLDDSDDA
IFEDAREHHSTTEKLHESDVVVKEQSPEKSLSEAPESKTPKTVVVTESEEASRSAIDSDD
EVETKTSRSTSRKKATDTLKADTPSSSTRSRDHSENDDKSDSTPRTRSRHSSTAVSESKS
TQLFSKEQDHNMWKSRWEDCARELQKLKDFSQIVDNKVIQDDYYKKICLHPMNLKIIAKN
IENHISTLKSDVDRDFVLMCTNIMMINNKGQKFDEIVQQFMRDGREIIDSHMRVDDAYKS
YRKQIKKQVL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 21 | g997.t1 | CDD | cd04369 | Bromodomain | 750 | 828 | 2.90321E-6 |
| 20 | g997.t1 | Coils | Coil | Coil | 117 | 144 | - |
| 19 | g997.t1 | Gene3D | G3DSA:1.20.920.10 | Histone Acetyltransferase; Chain A | 709 | 832 | 9.8E-10 |
| 8 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 82 | 106 | - |
| 5 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 183 | 205 | - |
| 6 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 183 | 250 | - |
| 10 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 206 | 250 | - |
| 13 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 394 | 413 | - |
| 11 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 489 | 728 | - |
| 12 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 491 | 519 | - |
| 18 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 520 | 558 | - |
| 7 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 559 | 576 | - |
| 9 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 577 | 635 | - |
| 15 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 636 | 651 | - |
| 16 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 652 | 679 | - |
| 14 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 686 | 706 | - |
| 17 | g997.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 707 | 728 | - |
| 2 | g997.t1 | PANTHER | PTHR15398:SF4 | BROMODOMAIN CONTAINING 8 | 7 | 812 | 1.1E-36 |
| 3 | g997.t1 | PANTHER | PTHR15398 | BROMODOMAIN-CONTAINING PROTEIN 8 | 7 | 812 | 1.1E-36 |
| 1 | g997.t1 | Pfam | PF00439 | Bromodomain | 746 | 813 | 1.3E-5 |
| 4 | g997.t1 | SUPERFAMILY | SSF47370 | Bromodomain | 743 | 833 | 1.1E-9 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K11321 (bromodomain-containing protein 8)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
