General information for g10037.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ras-specific guanine nucleotide-releasing factor 1.
Parent gene
- The parent gene g10037 is located on chr_1: 6910892..6912501 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10037 | g10037.t2 | isoform | g10037.t2 | 6896284 | 6911937 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon1 | 6896284 | 6896373 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS1 | 6896284 | 6896373 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon2 | 6897974 | 6898039 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS2 | 6897974 | 6898039 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon3 | 6898160 | 6898342 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS3 | 6898160 | 6898342 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon4 | 6898406 | 6898512 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS4 | 6898406 | 6898512 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon5 | 6898663 | 6898810 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS5 | 6898663 | 6898810 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon6 | 6899279 | 6899617 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS6 | 6899279 | 6899617 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon7 | 6899730 | 6899919 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS7 | 6899730 | 6899919 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon8 | 6901080 | 6901214 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS8 | 6901080 | 6901214 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon9 | 6901296 | 6901467 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS9 | 6901296 | 6901467 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon10 | 6901539 | 6901657 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS10 | 6901539 | 6901657 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon11 | 6901992 | 6902115 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS11 | 6901992 | 6902115 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon12 | 6902229 | 6902566 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS12 | 6902229 | 6902566 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon13 | 6902635 | 6902847 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS13 | 6902635 | 6902847 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon14 | 6903018 | 6903167 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS14 | 6903018 | 6903167 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon15 | 6903405 | 6903512 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS15 | 6903405 | 6903512 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon16 | 6903602 | 6904235 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS16 | 6903602 | 6904235 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon17 | 6904428 | 6904536 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS17 | 6904428 | 6904536 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon18 | 6904613 | 6904763 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS18 | 6904613 | 6904763 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon19 | 6904846 | 6904972 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS19 | 6904846 | 6904972 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon20 | 6907330 | 6907367 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS20 | 6907330 | 6907367 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon21 | 6907448 | 6907556 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS21 | 6907448 | 6907556 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon22 | 6907623 | 6907827 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS22 | 6907623 | 6907827 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon23 | 6907898 | 6907995 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS23 | 6907898 | 6907995 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon24 | 6910892 | 6910930 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS24 | 6910892 | 6910930 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon25 | 6911057 | 6911137 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS25 | 6911057 | 6911137 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon26 | 6911243 | 6911405 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS26 | 6911243 | 6911405 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon27 | 6911471 | 6911668 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS27 | 6911471 | 6911668 |
| chr_1 | g10037 | g10037.t2 | exon | g10037.t2.exon28 | 6911749 | 6911937 |
| chr_1 | g10037 | g10037.t2 | cds | g10037.t2.CDS28 | 6911749 | 6911937 |
| chr_1 | g10037 | g10037.t2 | TSS | g10037.t2 | NA | NA |
| chr_1 | g10037 | g10037.t2 | TTS | g10037.t2 | NA | NA |
Sequences
>g10037.t2 Gene=g10037 Length=4623
ATGCTCAGTCCAAAAATGCAGAGATCCGTTCGAGTCAACGAAAATCAATTGATTATGCTC
TCTGACAAAGCTCAACATGATAACAGTATGCAAGGATATCTTTATAAGCGAACCTCAAGC
GATAGATGGCAGCTACGATTTTTTCTACTGTATCAAAATCTTTTATTTTATTATGAATCT
GAAACATCGACGAGGCCGTCGGGCATTATATTTTTAGAAGGTTGTTACTGTGAGCGACTT
GTCTCAGCTCCCGCATGTATTGCACCTGGGTCGCCTCTACTCTCGAACAATAATTCAAAT
GCAAACATTTCAAAAACTAACAAGGAAGAAAAACTTCAACACTGCTTCACTATCTCATAT
CGTCGTGAAAATCAGAGACATTACGAGTTGAAATGTAACACAGAATCTGAATGCTCTGCA
TGGATAATAGCAATAAGAGAAGCGAGCTTCAACAAGCTACTTCTTCAAAAGGAAGAACTT
GAACAGAAGCATGTTCATTTATTACAAGTGGTTGAAAGTGAGAAAACTGCAAAATGGCAA
TACACTCAGCAGTGTGAGGAACTCGCCTCAGAGATAAGAAAACTTCGAGCTGAGATTTGT
GTATTGCGAAAAGAAACAAAACGCTCATCATTCTCAGCAACTCCCGTTGGTAGAGGAAGT
TTTAGTGCTGGCGCTACAAATGAACATTCTGAAACCATGGGCATAATTGAGACGTCAAAT
CTAGCAAATTTATGCGAGTCTGTACAAGATTCTATTGAGTTACGAAAGATCAAAAAAGTT
CAAAGTTTTTTCCGTGGCTGGTTGTGTCGACGGCGCTGGAAGCAAATTGTCGAAGAATAC
ATCAAATCACCACACGCCGAGAGCATGCGAAAGCGAAATAGTCTCGTGTTCTCGATGGTT
GAAGCAGAAGAGGAGTATTTGGAACAGCTGGAAGTTCTCGTGTCATGCTTTCTTCGTCCT
TTTAAAATGGCAGCATCTTCAAAACGTCCACCATGCTCGCACGAAGATGTCAACTCAATT
TTTCTCAACTCTGAAACTGTTTTATTCCTTCATCAAATCTTTCTGAAGGGGCTAACATCA
AGACTCGAGTCCTGGCCAACACTCGTTCTCGGTAAGACTATAAGCGACTTGTTTGACATG
CTATTGCCAATGTTGAGTATCTATCAAGAATATGTGAGAAATCATCACTATAGTCTTCAA
GTACTTACAGAGTGCAAAAGCAATCCAGCTTTCGCAACTGTTCTTAAGAGACTAGAAGCA
GCAAAACCACAATGTAAGGGACGAAGTCTAGAGCAGTTCCTTACCTATCCGATGCATCAG
ATTCCACGTTATATCATCACGCTCCATGAACTGCTCGCACACACGCCCTTTGATCATGTC
GAGAGGCCAAGCCTACAAAATGCTCGACAACAACTCGAAGATCTTAGTCGACAAATGCAC
GATGAAGTTTCTGAGACAGAAAATTTGCGAAAGAATCTAGCAGTAGAGCGAATGATTGTG
GAGGGCTGTGACATTCTATTAGATGTTAATCAAGTATTTGTTCGTCAAGGAAGTTTAGTT
CAAGTGCCTCCAGGCCGAGGCCGTATTCGTAGTAGATTAGCATCGTTTAAGAGCGAACGT
GAATCAGTACGTCAATGTTTCCTCTTTTCAAACCACATGATAATAGCGACAAGAACATCT
GCTGGAAGATTACATTTGTTACCTGATGTTGGTAAAATTCCATTAGTGGACGCAACACTA
ATTGAAGATCCAAGTGAAGCTGGAAATGACGATGAAGAGTCACTTTGTTCTGCATCAACA
CAAAGCAGCAATTTGAGTGTAACTGACCCAGTCAATGCAAATAACCGTGACTTTAAAATA
ATCGTTGATGGAAAATCAGGACAAAGGCATTCAATTCATCTTGTTGCACCGACAGCTCAA
GATAAAGAAGCATGGATTAGTGATATTTCACAATGTTTAGACAACATTCATATGCATTCA
TTGTTATCACCTGGTATTGGCACAACTGCAGCTTCAATGTTTACAGGTCATCAAGCACTA
CGAGCTGACCCGCATTTATTCAAGGACGATGTTGATATAAGGTTCTCGCGAACACTCAAT
TCTTGCAAATTGCCACAAATTCGCTATGCCACACCAGAAAAGTTATTGCAACGACTCACC
GATTTGCGATTTCTATCCATCGATTTTCTCAACACCTTTTTACTCACATATCGTGTTTTT
ACAGATGGTGAAACTGTGCTTGGTGCGCTAAAAAAGGTGTTTTATGATCCACCTATTGAA
CCATGTGATTGTGAACCACAAACTGATCTTTTAGAGCTTCCTTATCAAAATGACAACCAT
CCAAGACGAACGAGTGGTGCAAGTTCCGTTTCAGGGTATTGTTCAGAAGGTGCAGATAGA
GATCGCTCAATGAGTGGCGATTCAGTTGGATTGCGCTTTAGACCATCACGCAGAAATTTA
TATCAACAACAATCAACACAAGATCAAGAGACAACCTTGACCTGGATACCGGAAACTGTT
GCATCAGAAGTAGAAATTGAGGTCAATCCTGAAGTAACAATTGTACATGGCAGTGAGAGT
GATGAGGCAGTTACAAAACAAACAAGTGTTCCACAAGATGAAAGCTATTTAGGAGTTCCT
TCCTCAATTTCTGCATCAGGCAGTGCAGATACGTTAGTACCAAGCGGTCCTTCGTCACCA
TCAAATATCAGCAATGTAACATTGGTCGGCTCAACGGGAAGTGGTGAAAAATGTGACGAA
ACACCCACAGAGACTTCAACAACTCCATTTAAATATGGGAAAGCGCCCACATCTCCATTG
CCCGAACGCATCATTCCAAAACGTCCACCACGCACGATTGAACAACAGCAATCACTTAGT
ACAGATTCAACAACAATAACAGTCTCGAAAAGTCAACAGCTACCTCAAACGACAATTGTC
AAATCAATTAGCGAAACAAAGCCGAGCATAATAAAAATTGCTCCACCAACAACAAATGTA
TCGACAAATACTGTTACAATAACAACATCAACATTAATCTCAACGGCTGCTTTAACAGCT
TCCTCTACAACAAAAACATCAATAACCACTCCATCAATAGGTGTAACATTCGACAGACGT
CCGAGTGTGGGCTATAATGTAATACCGCACGCAGCACTTTGTCAGCATCGATACAGTTTG
CAACTAAATGGCGAAGGCGGTGGAAATACTGCTAGTGGTCAAAAGAATTTCGAAAAGACC
AGTCCTCGTTTGACACATAGAAAATTTTCAGCACCAAAAACACCAGAACGACAAAGAAAA
TCTTTTGGTACACCGCAACCGCCAAGAAGATTCTCCGAAAGCGATGATGAAATGGCATCA
TTATACACACCTAGAGGATCACTTGGAGGAATTAGTTTGAGTACAATTTCATCAAGAGCT
TCTATGCAACATGATCCACATATTCCACATTGTTCGAGCAAAGTTGGTGTCGTGATTACG
TCATTTAGACAGGCCCAAAGGAGGTCCAGTACATCGACAGCTGCTGCGGCTTTTGCCATC
GCAACCTCCGCCTCATCAAATCCACGAGATGAACCGGACATTGAAACGAAAAGTCGGAAG
GATTCTGTTGTGAGCTCACCGGCAACAATGCGTGTTCTTAATGTTTTAAGGCATTGGGTT
TCAAAACATTTTCAAGATTTTGAACAAGATGAGAAACTTCGATCGCAAACAATTGAATTC
CTCGATGAGATTACATGCAGCCCTAATTTACTACCTGGAGAGCATCGAGCCGCCTCACAA
TTACTGAGATTACTTACTCGTGATGATATCGATTGTGGGAAGAAGAATTTGGAATTGCTT
TTGGCACCACCCACTTCTCCAAGCAAGGAGAGCATAGAAACGCTATCAGCATTAGAAATA
GCAGAACAAATGACGTATTTAGATCATCAAATTTTTCTTGCTATAAGGAGCGAAGAATTT
TTGGGTCAAGCTTGGATGAAGTCTGATAAACGGAATAGAGCGGAGCACATAATTCAGATG
ACGAAGAGATTTAATGATGGCTCTAGGCTCGTGGGCTCAGAAATTGTTTCTAGATGTAAT
ATGGCAGCACGTGTTGCAGCAATTGAGAAATGGACGGCTGTTGCTGATATTTGTCGATGT
TTACATAATTTCAATGGTGTTTTACAAATTTGTGCTGCTTTTACGAGTGCACCGATTTAT
CGAATGAAAAAAACATGGGATAAAGTGCCCAAAAATATTAAGTCAACCATAACAAAATTG
CAAGCAGTCGTTTGCTCAGATGGTCGATTTCGTGTAATGCGTGAGGCATTACATCGTTGT
GATCCACCATGTATACCATATCTAGGCATGTATTTAACTGATTTGTCATTTATTGAAGAA
GGCACACCCGATTTTACGCCCGATGGTTTGTTAAATTTTTCGAAAATGAGAATGATTGCG
CACGTAATTCGAGAGATTCGACACTTTCAACAAACGCCATACAAAATCGATCACATTCCA
AAAGTGACTTCTTACTTACTCGACACTTCTCTACTTCTTGATGATGACGAGATGTATCAT
AAATCATTGCGAATTGAGCCAAGAAGTTCACGATTAAGTGCACCAAATGTGACACTAGTA
TAA
>g10037.t2 Gene=g10037 Length=1540
MLSPKMQRSVRVNENQLIMLSDKAQHDNSMQGYLYKRTSSDRWQLRFFLLYQNLLFYYES
ETSTRPSGIIFLEGCYCERLVSAPACIAPGSPLLSNNNSNANISKTNKEEKLQHCFTISY
RRENQRHYELKCNTESECSAWIIAIREASFNKLLLQKEELEQKHVHLLQVVESEKTAKWQ
YTQQCEELASEIRKLRAEICVLRKETKRSSFSATPVGRGSFSAGATNEHSETMGIIETSN
LANLCESVQDSIELRKIKKVQSFFRGWLCRRRWKQIVEEYIKSPHAESMRKRNSLVFSMV
EAEEEYLEQLEVLVSCFLRPFKMAASSKRPPCSHEDVNSIFLNSETVLFLHQIFLKGLTS
RLESWPTLVLGKTISDLFDMLLPMLSIYQEYVRNHHYSLQVLTECKSNPAFATVLKRLEA
AKPQCKGRSLEQFLTYPMHQIPRYIITLHELLAHTPFDHVERPSLQNARQQLEDLSRQMH
DEVSETENLRKNLAVERMIVEGCDILLDVNQVFVRQGSLVQVPPGRGRIRSRLASFKSER
ESVRQCFLFSNHMIIATRTSAGRLHLLPDVGKIPLVDATLIEDPSEAGNDDEESLCSAST
QSSNLSVTDPVNANNRDFKIIVDGKSGQRHSIHLVAPTAQDKEAWISDISQCLDNIHMHS
LLSPGIGTTAASMFTGHQALRADPHLFKDDVDIRFSRTLNSCKLPQIRYATPEKLLQRLT
DLRFLSIDFLNTFLLTYRVFTDGETVLGALKKVFYDPPIEPCDCEPQTDLLELPYQNDNH
PRRTSGASSVSGYCSEGADRDRSMSGDSVGLRFRPSRRNLYQQQSTQDQETTLTWIPETV
ASEVEIEVNPEVTIVHGSESDEAVTKQTSVPQDESYLGVPSSISASGSADTLVPSGPSSP
SNISNVTLVGSTGSGEKCDETPTETSTTPFKYGKAPTSPLPERIIPKRPPRTIEQQQSLS
TDSTTITVSKSQQLPQTTIVKSISETKPSIIKIAPPTTNVSTNTVTITTSTLISTAALTA
SSTTKTSITTPSIGVTFDRRPSVGYNVIPHAALCQHRYSLQLNGEGGGNTASGQKNFEKT
SPRLTHRKFSAPKTPERQRKSFGTPQPPRRFSESDDEMASLYTPRGSLGGISLSTISSRA
SMQHDPHIPHCSSKVGVVITSFRQAQRRSSTSTAAAAFAIATSASSNPRDEPDIETKSRK
DSVVSSPATMRVLNVLRHWVSKHFQDFEQDEKLRSQTIEFLDEITCSPNLLPGEHRAASQ
LLRLLTRDDIDCGKKNLELLLAPPTSPSKESIETLSALEIAEQMTYLDHQIFLAIRSEEF
LGQAWMKSDKRNRAEHIIQMTKRFNDGSRLVGSEIVSRCNMAARVAAIEKWTAVADICRC
LHNFNGVLQICAAFTSAPIYRMKKTWDKVPKNIKSTITKLQAVVCSDGRFRVMREALHRC
DPPCIPYLGMYLTDLSFIEEGTPDFTPDGLLNFSKMRMIAHVIREIRHFQQTPYKIDHIP
KVTSYLLDTSLLLDDDEMYHKSLRIEPRSSRLSAPNVTLV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 24 | g10037.t2 | CDD | cd00160 | RhoGEF | 292 | 480 | 5.42475E-39 |
| 26 | g10037.t2 | CDD | cd06224 | REM | 1191 | 1267 | 1.12291E-10 |
| 25 | g10037.t2 | CDD | cd00155 | RasGEF | 1292 | 1502 | 1.99946E-65 |
| 23 | g10037.t2 | Coils | Coil | Coil | 178 | 198 | - |
| 22 | g10037.t2 | Coils | Coil | Coil | 465 | 492 | - |
| 17 | g10037.t2 | Gene3D | G3DSA:2.30.29.30 | - | 10 | 149 | 2.0E-21 |
| 20 | g10037.t2 | Gene3D | G3DSA:1.20.900.10 | - | 280 | 491 | 3.2E-43 |
| 16 | g10037.t2 | Gene3D | G3DSA:2.30.29.30 | - | 492 | 676 | 1.7E-24 |
| 19 | g10037.t2 | Gene3D | G3DSA:1.20.870.10 | Son of sevenless (SoS) protein Chain: S domain 1 | 677 | 777 | 1.8E-10 |
| 18 | g10037.t2 | Gene3D | G3DSA:1.20.870.10 | Son of sevenless (SoS) protein Chain: S domain 1 | 1164 | 1269 | 1.3E-10 |
| 21 | g10037.t2 | Gene3D | G3DSA:1.10.840.10 | Son of sevenless (Sos) protein Chain | 1293 | 1530 | 2.8E-87 |
| 38 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 780 | 808 | - |
| 35 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 911 | 933 | - |
| 37 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 911 | 936 | - |
| 33 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1067 | 1116 | - |
| 34 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1080 | 1095 | - |
| 36 | g10037.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1183 | 1202 | - |
| 7 | g10037.t2 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 100 | 208 | 0.0 |
| 10 | g10037.t2 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 100 | 208 | 0.0 |
| 8 | g10037.t2 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 253 | 757 | 0.0 |
| 11 | g10037.t2 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 253 | 757 | 0.0 |
| 6 | g10037.t2 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 1161 | 1528 | 0.0 |
| 9 | g10037.t2 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 1161 | 1528 | 0.0 |
| 4 | g10037.t2 | Pfam | PF00169 | PH domain | 30 | 149 | 7.8E-17 |
| 3 | g10037.t2 | Pfam | PF00621 | RhoGEF domain | 298 | 479 | 3.5E-33 |
| 2 | g10037.t2 | Pfam | PF00618 | RasGEF N-terminal motif | 706 | 764 | 1.0E-13 |
| 1 | g10037.t2 | Pfam | PF00618 | RasGEF N-terminal motif | 1194 | 1240 | 1.1E-6 |
| 5 | g10037.t2 | Pfam | PF00617 | RasGEF domain | 1299 | 1477 | 1.1E-53 |
| 32 | g10037.t2 | ProSitePatterns | PS00720 | Ras Guanine-nucleotide exchange factors domain signature. | 1445 | 1475 | - |
| 43 | g10037.t2 | ProSiteProfiles | PS50003 | PH domain profile. | 27 | 150 | 16.048 |
| 40 | g10037.t2 | ProSiteProfiles | PS50096 | IQ motif profile. | 253 | 282 | 8.498 |
| 39 | g10037.t2 | ProSiteProfiles | PS50010 | Dbl homology (DH) domain profile. | 291 | 482 | 28.74 |
| 42 | g10037.t2 | ProSiteProfiles | PS50003 | PH domain profile. | 512 | 654 | 7.785 |
| 41 | g10037.t2 | ProSiteProfiles | PS50009 | Ras guanine-nucleotide exchange factors catalytic domain profile. | 1296 | 1528 | 66.205 |
| 30 | g10037.t2 | SMART | SM00233 | PH_update | 28 | 152 | 8.1E-21 |
| 28 | g10037.t2 | SMART | SM00325 | RhoGEF_3 | 295 | 481 | 1.8E-48 |
| 29 | g10037.t2 | SMART | SM00233 | PH_update | 513 | 656 | 1.3E-6 |
| 27 | g10037.t2 | SMART | SM00229 | rasgefn_5 | 702 | 841 | 0.0035 |
| 31 | g10037.t2 | SMART | SM00147 | RasGEF_3 | 1292 | 1529 | 1.3E-81 |
| 12 | g10037.t2 | SUPERFAMILY | SSF50729 | PH domain-like | 27 | 150 | 3.08E-21 |
| 15 | g10037.t2 | SUPERFAMILY | SSF48065 | DBL homology domain (DH-domain) | 272 | 500 | 1.22E-45 |
| 13 | g10037.t2 | SUPERFAMILY | SSF50729 | PH domain-like | 491 | 655 | 1.26E-10 |
| 14 | g10037.t2 | SUPERFAMILY | SSF48366 | Ras GEF | 696 | 1532 | 1.7E-115 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0046578 | regulation of Ras protein signal transduction | BP |
| GO:0005515 | protein binding | MF |
| GO:0007264 | small GTPase mediated signal transduction | BP |
| GO:0035023 | regulation of Rho protein signal transduction | BP |
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04349 (Ras-specific guanine nucleotide-releasing factor 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed