General information for g10037.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ras-specific guanine nucleotide-releasing factor 1.
Parent gene
- The parent gene g10037 is located on chr_1: 6910892..6912501 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10037 | g10037.t3 | isoform | g10037.t3 | 6896284 | 6911937 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon1 | 6896284 | 6896373 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS1 | 6896284 | 6896373 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon2 | 6897974 | 6898039 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS2 | 6897974 | 6898039 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon3 | 6898160 | 6898342 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS3 | 6898160 | 6898342 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon4 | 6898406 | 6898512 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS4 | 6898406 | 6898512 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon5 | 6898663 | 6898810 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS5 | 6898663 | 6898810 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon6 | 6899279 | 6899617 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS6 | 6899279 | 6899617 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon7 | 6899730 | 6899907 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS7 | 6899730 | 6899907 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon8 | 6901080 | 6901214 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS8 | 6901080 | 6901214 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon9 | 6901296 | 6901467 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS9 | 6901296 | 6901467 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon10 | 6901539 | 6901657 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS10 | 6901539 | 6901657 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon11 | 6901992 | 6902115 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS11 | 6901992 | 6902115 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon12 | 6902229 | 6902566 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS12 | 6902229 | 6902566 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon13 | 6902635 | 6902847 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS13 | 6902635 | 6902847 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon14 | 6903018 | 6903167 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS14 | 6903018 | 6903167 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon15 | 6903405 | 6903512 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS15 | 6903405 | 6903512 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon16 | 6903602 | 6904235 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS16 | 6903602 | 6904235 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon17 | 6904428 | 6904536 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS17 | 6904428 | 6904536 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon18 | 6904613 | 6904763 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS18 | 6904613 | 6904763 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon19 | 6904846 | 6904972 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS19 | 6904846 | 6904972 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon20 | 6907330 | 6907367 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS20 | 6907330 | 6907367 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon21 | 6907448 | 6907556 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS21 | 6907448 | 6907556 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon22 | 6907623 | 6907827 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS22 | 6907623 | 6907827 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon23 | 6907898 | 6907995 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS23 | 6907898 | 6907995 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon24 | 6910892 | 6910930 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS24 | 6910892 | 6910930 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon25 | 6911057 | 6911137 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS25 | 6911057 | 6911137 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon26 | 6911243 | 6911405 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS26 | 6911243 | 6911405 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon27 | 6911471 | 6911668 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS27 | 6911471 | 6911668 |
| chr_1 | g10037 | g10037.t3 | exon | g10037.t3.exon28 | 6911749 | 6911937 |
| chr_1 | g10037 | g10037.t3 | cds | g10037.t3.CDS28 | 6911749 | 6911937 |
| chr_1 | g10037 | g10037.t3 | TSS | g10037.t3 | NA | NA |
| chr_1 | g10037 | g10037.t3 | TTS | g10037.t3 | NA | NA |
Sequences
>g10037.t3 Gene=g10037 Length=4611
ATGCTCAGTCCAAAAATGCAGAGATCCGTTCGAGTCAACGAAAATCAATTGATTATGCTC
TCTGACAAAGCTCAACATGATAACAGTATGCAAGGATATCTTTATAAGCGAACCTCAAGC
GATAGATGGCAGCTACGATTTTTTCTACTGTATCAAAATCTTTTATTTTATTATGAATCT
GAAACATCGACGAGGCCGTCGGGCATTATATTTTTAGAAGGTTGTTACTGTGAGCGACTT
GTCTCAGCTCCCGCATGTATTGCACCTGGGTCGCCTCTACTCTCGAACAATAATTCAAAT
GCAAACATTTCAAAAACTAACAAGGAAGAAAAACTTCAACACTGCTTCACTATCTCATAT
CGTCGTGAAAATCAGAGACATTACGAGTTGAAATGTAACACAGAATCTGAATGCTCTGCA
TGGATAATAGCAATAAGAGAAGCGAGCTTCAACAAGCTACTTCTTCAAAAGGAAGAACTT
GAACAGAAGCATGTTCATTTATTACAAGTGGTTGAAAGTGAGAAAACTGCAAAATGGCAA
TACACTCAGCAGTGTGAGGAACTCGCCTCAGAGATAAGAAAACTTCGAGCTGAGATTTGT
GTATTGCGAAAAGAAACAAAACGCTCATCATTCTCAGCAACTCCCGTTGGTAGAGGAAGT
TTTAGTGCTGGCGCTACAAATGAACATTCTGAAACCATGGGCATAATTGAGACGTCAAAT
CTAGCAAATTTATGCGAGTCTGTACAAGATTCTATTGAGTTACGAAAGATCAAAAAAGTT
CAAAGTTTTTTCCGTGGCTGGTTGTGTCGACGGCGCTGGAAGCAAATTGTCGAAGAATAC
ATCAAATCACCACACGCCGAGAGCATGCGAAAGCGAAATAGTCTCGTGTTCTCGATGGTT
GAAGCAGAAGAGGAGTATTTGGAACAGCTGGAAGTTCTCGTGTCATGCTTTCTTCGTCCT
TTTAAAATGGCAGCATCTTCAAAACGTCCACCATGCTCGCACGAAGATGTCAACTCAATT
TTTCTCAACTCTGAAACTGTTTTATTCCTTCATCAAATCTTTCTGAAGGGGCTAACATCA
AGACTCGAGTCCTGGCCAACACTCGTTCTCGGCGACTTGTTTGACATGCTATTGCCAATG
TTGAGTATCTATCAAGAATATGTGAGAAATCATCACTATAGTCTTCAAGTACTTACAGAG
TGCAAAAGCAATCCAGCTTTCGCAACTGTTCTTAAGAGACTAGAAGCAGCAAAACCACAA
TGTAAGGGACGAAGTCTAGAGCAGTTCCTTACCTATCCGATGCATCAGATTCCACGTTAT
ATCATCACGCTCCATGAACTGCTCGCACACACGCCCTTTGATCATGTCGAGAGGCCAAGC
CTACAAAATGCTCGACAACAACTCGAAGATCTTAGTCGACAAATGCACGATGAAGTTTCT
GAGACAGAAAATTTGCGAAAGAATCTAGCAGTAGAGCGAATGATTGTGGAGGGCTGTGAC
ATTCTATTAGATGTTAATCAAGTATTTGTTCGTCAAGGAAGTTTAGTTCAAGTGCCTCCA
GGCCGAGGCCGTATTCGTAGTAGATTAGCATCGTTTAAGAGCGAACGTGAATCAGTACGT
CAATGTTTCCTCTTTTCAAACCACATGATAATAGCGACAAGAACATCTGCTGGAAGATTA
CATTTGTTACCTGATGTTGGTAAAATTCCATTAGTGGACGCAACACTAATTGAAGATCCA
AGTGAAGCTGGAAATGACGATGAAGAGTCACTTTGTTCTGCATCAACACAAAGCAGCAAT
TTGAGTGTAACTGACCCAGTCAATGCAAATAACCGTGACTTTAAAATAATCGTTGATGGA
AAATCAGGACAAAGGCATTCAATTCATCTTGTTGCACCGACAGCTCAAGATAAAGAAGCA
TGGATTAGTGATATTTCACAATGTTTAGACAACATTCATATGCATTCATTGTTATCACCT
GGTATTGGCACAACTGCAGCTTCAATGTTTACAGGTCATCAAGCACTACGAGCTGACCCG
CATTTATTCAAGGACGATGTTGATATAAGGTTCTCGCGAACACTCAATTCTTGCAAATTG
CCACAAATTCGCTATGCCACACCAGAAAAGTTATTGCAACGACTCACCGATTTGCGATTT
CTATCCATCGATTTTCTCAACACCTTTTTACTCACATATCGTGTTTTTACAGATGGTGAA
ACTGTGCTTGGTGCGCTAAAAAAGGTGTTTTATGATCCACCTATTGAACCATGTGATTGT
GAACCACAAACTGATCTTTTAGAGCTTCCTTATCAAAATGACAACCATCCAAGACGAACG
AGTGGTGCAAGTTCCGTTTCAGGGTATTGTTCAGAAGGTGCAGATAGAGATCGCTCAATG
AGTGGCGATTCAGTTGGATTGCGCTTTAGACCATCACGCAGAAATTTATATCAACAACAA
TCAACACAAGATCAAGAGACAACCTTGACCTGGATACCGGAAACTGTTGCATCAGAAGTA
GAAATTGAGGTCAATCCTGAAGTAACAATTGTACATGGCAGTGAGAGTGATGAGGCAGTT
ACAAAACAAACAAGTGTTCCACAAGATGAAAGCTATTTAGGAGTTCCTTCCTCAATTTCT
GCATCAGGCAGTGCAGATACGTTAGTACCAAGCGGTCCTTCGTCACCATCAAATATCAGC
AATGTAACATTGGTCGGCTCAACGGGAAGTGGTGAAAAATGTGACGAAACACCCACAGAG
ACTTCAACAACTCCATTTAAATATGGGAAAGCGCCCACATCTCCATTGCCCGAACGCATC
ATTCCAAAACGTCCACCACGCACGATTGAACAACAGCAATCACTTAGTACAGATTCAACA
ACAATAACAGTCTCGAAAAGTCAACAGCTACCTCAAACGACAATTGTCAAATCAATTAGC
GAAACAAAGCCGAGCATAATAAAAATTGCTCCACCAACAACAAATGTATCGACAAATACT
GTTACAATAACAACATCAACATTAATCTCAACGGCTGCTTTAACAGCTTCCTCTACAACA
AAAACATCAATAACCACTCCATCAATAGGTGTAACATTCGACAGACGTCCGAGTGTGGGC
TATAATGTAATACCGCACGCAGCACTTTGTCAGCATCGATACAGTTTGCAACTAAATGGC
GAAGGCGGTGGAAATACTGCTAGTGGTCAAAAGAATTTCGAAAAGACCAGTCCTCGTTTG
ACACATAGAAAATTTTCAGCACCAAAAACACCAGAACGACAAAGAAAATCTTTTGGTACA
CCGCAACCGCCAAGAAGATTCTCCGAAAGCGATGATGAAATGGCATCATTATACACACCT
AGAGGATCACTTGGAGGAATTAGTTTGAGTACAATTTCATCAAGAGCTTCTATGCAACAT
GATCCACATATTCCACATTGTTCGAGCAAAGTTGGTGTCGTGATTACGTCATTTAGACAG
GCCCAAAGGAGGTCCAGTACATCGACAGCTGCTGCGGCTTTTGCCATCGCAACCTCCGCC
TCATCAAATCCACGAGATGAACCGGACATTGAAACGAAAAGTCGGAAGGATTCTGTTGTG
AGCTCACCGGCAACAATGCGTGTTCTTAATGTTTTAAGGCATTGGGTTTCAAAACATTTT
CAAGATTTTGAACAAGATGAGAAACTTCGATCGCAAACAATTGAATTCCTCGATGAGATT
ACATGCAGCCCTAATTTACTACCTGGAGAGCATCGAGCCGCCTCACAATTACTGAGATTA
CTTACTCGTGATGATATCGATTGTGGGAAGAAGAATTTGGAATTGCTTTTGGCACCACCC
ACTTCTCCAAGCAAGGAGAGCATAGAAACGCTATCAGCATTAGAAATAGCAGAACAAATG
ACGTATTTAGATCATCAAATTTTTCTTGCTATAAGGAGCGAAGAATTTTTGGGTCAAGCT
TGGATGAAGTCTGATAAACGGAATAGAGCGGAGCACATAATTCAGATGACGAAGAGATTT
AATGATGGCTCTAGGCTCGTGGGCTCAGAAATTGTTTCTAGATGTAATATGGCAGCACGT
GTTGCAGCAATTGAGAAATGGACGGCTGTTGCTGATATTTGTCGATGTTTACATAATTTC
AATGGTGTTTTACAAATTTGTGCTGCTTTTACGAGTGCACCGATTTATCGAATGAAAAAA
ACATGGGATAAAGTGCCCAAAAATATTAAGTCAACCATAACAAAATTGCAAGCAGTCGTT
TGCTCAGATGGTCGATTTCGTGTAATGCGTGAGGCATTACATCGTTGTGATCCACCATGT
ATACCATATCTAGGCATGTATTTAACTGATTTGTCATTTATTGAAGAAGGCACACCCGAT
TTTACGCCCGATGGTTTGTTAAATTTTTCGAAAATGAGAATGATTGCGCACGTAATTCGA
GAGATTCGACACTTTCAACAAACGCCATACAAAATCGATCACATTCCAAAAGTGACTTCT
TACTTACTCGACACTTCTCTACTTCTTGATGATGACGAGATGTATCATAAATCATTGCGA
ATTGAGCCAAGAAGTTCACGATTAAGTGCACCAAATGTGACACTAGTATAA
>g10037.t3 Gene=g10037 Length=1536
MLSPKMQRSVRVNENQLIMLSDKAQHDNSMQGYLYKRTSSDRWQLRFFLLYQNLLFYYES
ETSTRPSGIIFLEGCYCERLVSAPACIAPGSPLLSNNNSNANISKTNKEEKLQHCFTISY
RRENQRHYELKCNTESECSAWIIAIREASFNKLLLQKEELEQKHVHLLQVVESEKTAKWQ
YTQQCEELASEIRKLRAEICVLRKETKRSSFSATPVGRGSFSAGATNEHSETMGIIETSN
LANLCESVQDSIELRKIKKVQSFFRGWLCRRRWKQIVEEYIKSPHAESMRKRNSLVFSMV
EAEEEYLEQLEVLVSCFLRPFKMAASSKRPPCSHEDVNSIFLNSETVLFLHQIFLKGLTS
RLESWPTLVLGDLFDMLLPMLSIYQEYVRNHHYSLQVLTECKSNPAFATVLKRLEAAKPQ
CKGRSLEQFLTYPMHQIPRYIITLHELLAHTPFDHVERPSLQNARQQLEDLSRQMHDEVS
ETENLRKNLAVERMIVEGCDILLDVNQVFVRQGSLVQVPPGRGRIRSRLASFKSERESVR
QCFLFSNHMIIATRTSAGRLHLLPDVGKIPLVDATLIEDPSEAGNDDEESLCSASTQSSN
LSVTDPVNANNRDFKIIVDGKSGQRHSIHLVAPTAQDKEAWISDISQCLDNIHMHSLLSP
GIGTTAASMFTGHQALRADPHLFKDDVDIRFSRTLNSCKLPQIRYATPEKLLQRLTDLRF
LSIDFLNTFLLTYRVFTDGETVLGALKKVFYDPPIEPCDCEPQTDLLELPYQNDNHPRRT
SGASSVSGYCSEGADRDRSMSGDSVGLRFRPSRRNLYQQQSTQDQETTLTWIPETVASEV
EIEVNPEVTIVHGSESDEAVTKQTSVPQDESYLGVPSSISASGSADTLVPSGPSSPSNIS
NVTLVGSTGSGEKCDETPTETSTTPFKYGKAPTSPLPERIIPKRPPRTIEQQQSLSTDST
TITVSKSQQLPQTTIVKSISETKPSIIKIAPPTTNVSTNTVTITTSTLISTAALTASSTT
KTSITTPSIGVTFDRRPSVGYNVIPHAALCQHRYSLQLNGEGGGNTASGQKNFEKTSPRL
THRKFSAPKTPERQRKSFGTPQPPRRFSESDDEMASLYTPRGSLGGISLSTISSRASMQH
DPHIPHCSSKVGVVITSFRQAQRRSSTSTAAAAFAIATSASSNPRDEPDIETKSRKDSVV
SSPATMRVLNVLRHWVSKHFQDFEQDEKLRSQTIEFLDEITCSPNLLPGEHRAASQLLRL
LTRDDIDCGKKNLELLLAPPTSPSKESIETLSALEIAEQMTYLDHQIFLAIRSEEFLGQA
WMKSDKRNRAEHIIQMTKRFNDGSRLVGSEIVSRCNMAARVAAIEKWTAVADICRCLHNF
NGVLQICAAFTSAPIYRMKKTWDKVPKNIKSTITKLQAVVCSDGRFRVMREALHRCDPPC
IPYLGMYLTDLSFIEEGTPDFTPDGLLNFSKMRMIAHVIREIRHFQQTPYKIDHIPKVTS
YLLDTSLLLDDDEMYHKSLRIEPRSSRLSAPNVTLV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 24 | g10037.t3 | CDD | cd00160 | RhoGEF | 292 | 476 | 1.09751E-39 |
| 26 | g10037.t3 | CDD | cd06224 | REM | 1187 | 1263 | 1.11986E-10 |
| 25 | g10037.t3 | CDD | cd00155 | RasGEF | 1288 | 1498 | 1.86326E-65 |
| 23 | g10037.t3 | Coils | Coil | Coil | 178 | 198 | - |
| 22 | g10037.t3 | Coils | Coil | Coil | 461 | 488 | - |
| 17 | g10037.t3 | Gene3D | G3DSA:2.30.29.30 | - | 10 | 149 | 2.0E-21 |
| 20 | g10037.t3 | Gene3D | G3DSA:1.20.900.10 | - | 280 | 487 | 9.3E-43 |
| 16 | g10037.t3 | Gene3D | G3DSA:2.30.29.30 | - | 488 | 672 | 1.7E-24 |
| 18 | g10037.t3 | Gene3D | G3DSA:1.20.870.10 | Son of sevenless (SoS) protein Chain: S domain 1 | 673 | 773 | 1.8E-10 |
| 19 | g10037.t3 | Gene3D | G3DSA:1.20.870.10 | Son of sevenless (SoS) protein Chain: S domain 1 | 1160 | 1265 | 1.3E-10 |
| 21 | g10037.t3 | Gene3D | G3DSA:1.10.840.10 | Son of sevenless (Sos) protein Chain | 1289 | 1526 | 2.8E-87 |
| 35 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 776 | 804 | - |
| 34 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 907 | 932 | - |
| 36 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 907 | 929 | - |
| 38 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1063 | 1112 | - |
| 37 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1076 | 1091 | - |
| 33 | g10037.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1179 | 1198 | - |
| 6 | g10037.t3 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 100 | 208 | 0.0 |
| 9 | g10037.t3 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 100 | 208 | 0.0 |
| 8 | g10037.t3 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 253 | 753 | 0.0 |
| 11 | g10037.t3 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 253 | 753 | 0.0 |
| 7 | g10037.t3 | PANTHER | PTHR23113:SF187 | RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 | 1157 | 1524 | 0.0 |
| 10 | g10037.t3 | PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 1157 | 1524 | 0.0 |
| 4 | g10037.t3 | Pfam | PF00169 | PH domain | 30 | 149 | 7.8E-17 |
| 3 | g10037.t3 | Pfam | PF00621 | RhoGEF domain | 298 | 475 | 5.7E-33 |
| 1 | g10037.t3 | Pfam | PF00618 | RasGEF N-terminal motif | 702 | 760 | 1.0E-13 |
| 2 | g10037.t3 | Pfam | PF00618 | RasGEF N-terminal motif | 1190 | 1236 | 1.1E-6 |
| 5 | g10037.t3 | Pfam | PF00617 | RasGEF domain | 1295 | 1473 | 1.1E-53 |
| 32 | g10037.t3 | ProSitePatterns | PS00720 | Ras Guanine-nucleotide exchange factors domain signature. | 1441 | 1471 | - |
| 43 | g10037.t3 | ProSiteProfiles | PS50003 | PH domain profile. | 27 | 150 | 16.048 |
| 40 | g10037.t3 | ProSiteProfiles | PS50096 | IQ motif profile. | 253 | 282 | 8.498 |
| 39 | g10037.t3 | ProSiteProfiles | PS50010 | Dbl homology (DH) domain profile. | 291 | 478 | 28.983 |
| 42 | g10037.t3 | ProSiteProfiles | PS50003 | PH domain profile. | 508 | 650 | 7.785 |
| 41 | g10037.t3 | ProSiteProfiles | PS50009 | Ras guanine-nucleotide exchange factors catalytic domain profile. | 1292 | 1524 | 66.205 |
| 30 | g10037.t3 | SMART | SM00233 | PH_update | 28 | 152 | 8.1E-21 |
| 28 | g10037.t3 | SMART | SM00325 | RhoGEF_3 | 295 | 477 | 4.3E-50 |
| 29 | g10037.t3 | SMART | SM00233 | PH_update | 509 | 652 | 1.3E-6 |
| 27 | g10037.t3 | SMART | SM00229 | rasgefn_5 | 698 | 837 | 0.0035 |
| 31 | g10037.t3 | SMART | SM00147 | RasGEF_3 | 1288 | 1525 | 1.3E-81 |
| 12 | g10037.t3 | SUPERFAMILY | SSF50729 | PH domain-like | 27 | 150 | 2.83E-21 |
| 15 | g10037.t3 | SUPERFAMILY | SSF48065 | DBL homology domain (DH-domain) | 272 | 496 | 4.58E-46 |
| 13 | g10037.t3 | SUPERFAMILY | SSF50729 | PH domain-like | 487 | 651 | 1.26E-10 |
| 14 | g10037.t3 | SUPERFAMILY | SSF48366 | Ras GEF | 692 | 1528 | 1.7E-115 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0046578 | regulation of Ras protein signal transduction | BP |
| GO:0005515 | protein binding | MF |
| GO:0007264 | small GTPase mediated signal transduction | BP |
| GO:0035023 | regulation of Rho protein signal transduction | BP |
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04349 (Ras-specific guanine nucleotide-releasing factor 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed