General information for g10696.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sodium-coupled monocarboxylate transporter 2.
Parent gene
- The parent gene g10696 is located on chr_1: 11405373..11406491 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10696 | g10696.t1 | TSS | g10696.t1 | 11404019 | 11404019 |
| chr_1 | g10696 | g10696.t1 | isoform | g10696.t1 | 11404061 | 11406491 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon1 | 11404061 | 11404349 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS1 | 11404061 | 11404349 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon2 | 11404500 | 11404633 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS2 | 11404500 | 11404633 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon3 | 11404842 | 11404925 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS3 | 11404842 | 11404925 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon4 | 11404993 | 11405074 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS4 | 11404993 | 11405074 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon5 | 11405137 | 11405168 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS5 | 11405137 | 11405168 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon6 | 11405235 | 11405377 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS6 | 11405235 | 11405377 |
| chr_1 | g10696 | g10696.t1 | exon | g10696.t1.exon7 | 11405435 | 11406491 |
| chr_1 | g10696 | g10696.t1 | cds | g10696.t1.CDS7 | 11405435 | 11406491 |
| chr_1 | g10696 | g10696.t1 | TTS | g10696.t1 | 11406509 | 11406509 |
Sequences
>g10696.t1 Gene=g10696 Length=1821
ATGGACGAAAATCAGAAAAATCAACAAGGCAATGATGCCGTTGAGGATTTAAGAAATTCC
CTAAAGCACTTTGGGGTGGTGGATTATTTGGTATTTGGTATTTTACTTTTGTCGTGTACT
ATCGTTGGGCTTTATTTTGGCTATACAGATTATCAAAAAAAGAAACGAGTGAAAAATCAA
CGAAGAGGCTCGGAGGCAATGGACTATCTTGTAGGAGGACGAAACATGAAAGTCTTTCCC
GTGGCAATGTCTCTTGTAGCCTCTTGTATTTCTGGAATTGCATTGTTAGGCACAAGTACT
GAAATATACCTTTATGGAGCACAATACGCGTATATTTTAATTGGATACACAATAGCAGCT
TTAATTGTTAATTATACAATCATTCCAATCTTCCACGAACTTCAAATTACTTCTGCTTAT
GAGTACCTCCAAATGAGATTTGATGTTAAAGTATGTATTTTTGGTTCAGCAATGTATTCA
TTATCAACTTTATTATGGATGCCAATTGCTATTTATGTACCAGCTTTAGCATTCAGTCAA
ACAACTGGTATTGATGTACACATGATTACACCTATCGTGATGGGCATCTGCATATTTTAT
ACATGCTTAGGTGGCATAAAGGCTGTTGTATGGACTGATGTTATTCAGATTATGCTCATG
TATGGAACATTAGTTGTGATTATTGTTAGAGGCACTTCACTCGTTGGAGGATTTTCTGTA
GTCATAGAGAAAAATATTGAGAGTGGAAGACTGGCACCACCTGATTTTAATTTTGATCCT
ACTTTGAGAACTTCATTTTGGATAATGGTCATTGGTGGTTCATTTTTTCGTTTATATGCT
GGAATAAATCAATCAATGATACAGCGATATATGGCATTGAAGAACGTCCATGTAGCACGA
AAATGTCAATATGTCTATTTAGGTGGAATAATTATTTTGAATCTCATGTGTTATTACAAT
GGTCTACTACTTTATGCTTATTTTTATGATTGTGATCCATTGACAACAAAATTGGCAAAG
GCAAAAGATCAATTAATGCCACTCTTGGTGATGGAAATATTGCGAGATATTCCTGGAATG
CCTGGATTATTTATAGCTGGTGTGTTTTCTGCTGCACTTTCATCACTTTCAACAGCTTTA
AACTCATTTTCTGCGGTTGTTCTCGAGGACTTTTGCAAACCATTTGCAAAGGATGGTGTG
TCAGAACGAACAAGTGCAATAATAATGCGTATGACAGTGTTAGTGGTTGGAGTGATGAGC
GTAGCTCTTGTATATGTTGTGCAGCATATGGGATCCGTGCTTCAACTAGCATACACTATA
CCATCAGTTGCATTCGGGCCGATGTTGGGCATTTATATAATTGGACTTTGTATTCCGCAC
ATTGGAAAACGTGCGACATTCTATGGAGCTTTGACCGGATGTAGTGTAATGATTGCTTTC
ATTTCGAAAGTACAAATTGAAGTTGCTTTGGGCAAAATTAGTCACCCAATAAAACCAGTC
TCAATTGATGGTTGTACATACGATTTTGTAGCTACTAATATGACAACAAACATCAATGAG
CCTTCAGTTACGGAAAGAAATATCTTTCACATTTCATTTATATATTACACTCTACTGGGG
TCGGTTATCGTTATCGTAACATCAATACTATACAGTTTTATTGTGGGCTTCAATGATCTT
AGTGATGTCGATATTAATTTGCTTGCTCCTTTCCTGAGAAAATACTTTAAGAATGCAGAA
AGAGATGATGAAGACAAAAAGTACCAAATAATTCTTGACAGAGACTCTATTATAGATAAG
AAAAAAAATTGTGACGAATAA
>g10696.t1 Gene=g10696 Length=606
MDENQKNQQGNDAVEDLRNSLKHFGVVDYLVFGILLLSCTIVGLYFGYTDYQKKKRVKNQ
RRGSEAMDYLVGGRNMKVFPVAMSLVASCISGIALLGTSTEIYLYGAQYAYILIGYTIAA
LIVNYTIIPIFHELQITSAYEYLQMRFDVKVCIFGSAMYSLSTLLWMPIAIYVPALAFSQ
TTGIDVHMITPIVMGICIFYTCLGGIKAVVWTDVIQIMLMYGTLVVIIVRGTSLVGGFSV
VIEKNIESGRLAPPDFNFDPTLRTSFWIMVIGGSFFRLYAGINQSMIQRYMALKNVHVAR
KCQYVYLGGIIILNLMCYYNGLLLYAYFYDCDPLTTKLAKAKDQLMPLLVMEILRDIPGM
PGLFIAGVFSAALSSLSTALNSFSAVVLEDFCKPFAKDGVSERTSAIIMRMTVLVVGVMS
VALVYVVQHMGSVLQLAYTIPSVAFGPMLGIYIIGLCIPHIGKRATFYGALTGCSVMIAF
ISKVQIEVALGKISHPIKPVSIDGCTYDFVATNMTTNINEPSVTERNIFHISFIYYTLLG
SVIVIVTSILYSFIVGFNDLSDVDINLLAPFLRKYFKNAERDDEDKKYQIILDRDSIIDK
KKNCDE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 32 | g10696.t1 | CDD | cd11492 | SLC5sbd_NIS-SMVT | 27 | 554 | 0.0 |
| 4 | g10696.t1 | Gene3D | G3DSA:1.20.1730.10 | - | 58 | 563 | 1.6E-107 |
| 2 | g10696.t1 | PANTHER | PTHR42985 | SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER | 17 | 580 | 2.2E-225 |
| 3 | g10696.t1 | PANTHER | PTHR42985:SF5 | LP24461P | 17 | 580 | 2.2E-225 |
| 1 | g10696.t1 | Pfam | PF00474 | Sodium:solute symporter family | 69 | 473 | 4.6E-43 |
| 18 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 28 | - |
| 28 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 29 | 48 | - |
| 5 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 49 | 77 | - |
| 23 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 78 | 97 | - |
| 16 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 98 | 108 | - |
| 29 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 109 | 131 | - |
| 8 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 132 | 150 | - |
| 24 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 151 | 174 | - |
| 15 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 175 | 185 | - |
| 25 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 186 | 206 | - |
| 7 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 207 | 217 | - |
| 20 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 218 | 242 | - |
| 12 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 243 | 261 | - |
| 30 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 262 | 282 | - |
| 9 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 283 | 302 | - |
| 21 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 303 | 328 | - |
| 17 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 329 | 362 | - |
| 27 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 363 | 387 | - |
| 11 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 388 | 406 | - |
| 22 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 407 | 427 | - |
| 13 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 428 | 432 | - |
| 19 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 458 | - |
| 6 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 459 | 464 | - |
| 26 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 465 | 486 | - |
| 14 | g10696.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 487 | 532 | - |
| 31 | g10696.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 533 | 557 | - |
| 10 | g10696.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 558 | 606 | - |
| 46 | g10696.t1 | ProSiteProfiles | PS50283 | Sodium:solute symporter family profile. | 25 | 487 | 49.342 |
| 47 | g10696.t1 | TIGRFAM | TIGR00813 | sss: transporter, solute:sodium symporter (SSS) family | 69 | 473 | 1.5E-84 |
| 38 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 26 | 48 | - |
| 41 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 77 | 99 | - |
| 43 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 109 | 131 | - |
| 35 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 151 | 173 | - |
| 33 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 188 | 210 | - |
| 37 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 219 | 241 | - |
| 44 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 261 | 283 | - |
| 42 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 304 | 326 | - |
| 36 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 363 | 385 | - |
| 40 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 406 | 428 | - |
| 34 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 438 | 460 | - |
| 45 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 467 | 489 | - |
| 39 | g10696.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 533 | 555 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed