General information for g16975.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Peroxidase.
Parent gene
- The parent gene g16975 is located on chr_4: 11935024..11937590 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16975 | g16975.t1 | isoform | g16975.t1 | 11935024 | 11937590 |
| chr_4 | g16975 | g16975.t1 | exon | g16975.t1.exon1 | 11935024 | 11936145 |
| chr_4 | g16975 | g16975.t1 | cds | g16975.t1.CDS1 | 11935024 | 11936145 |
| chr_4 | g16975 | g16975.t1 | exon | g16975.t1.exon2 | 11936199 | 11936368 |
| chr_4 | g16975 | g16975.t1 | cds | g16975.t1.CDS2 | 11936199 | 11936368 |
| chr_4 | g16975 | g16975.t1 | exon | g16975.t1.exon3 | 11936699 | 11937026 |
| chr_4 | g16975 | g16975.t1 | cds | g16975.t1.CDS3 | 11936699 | 11937026 |
| chr_4 | g16975 | g16975.t1 | exon | g16975.t1.exon4 | 11937081 | 11937385 |
| chr_4 | g16975 | g16975.t1 | cds | g16975.t1.CDS4 | 11937081 | 11937385 |
| chr_4 | g16975 | g16975.t1 | exon | g16975.t1.exon5 | 11937443 | 11937590 |
| chr_4 | g16975 | g16975.t1 | cds | g16975.t1.CDS5 | 11937443 | 11937590 |
| chr_4 | g16975 | g16975.t1 | TSS | g16975.t1 | NA | NA |
| chr_4 | g16975 | g16975.t1 | TTS | g16975.t1 | NA | NA |
Sequences
>g16975.t1 Gene=g16975 Length=2073
ATGACGCTACGTCACAAAATTTCCCTTTCAATACTCACAATAATTGTTGATGTAATTTTG
ACATCAACAGCAGTCCATGTGCCAACATCATCAACATCATATGTGACATATCATTCATCA
TCATCACCAAATGCATACAATCCATTTGTCAATAAACAAATCACAAAACCAAACAGCAGT
TTCTACAGTCCATTTTTCAAAGCACCAGCACCAGTTCCATCACAAATGTGTCCAGCAACA
GCACTTCCACCATGTTCAAGATCACGTTACAGAACTCTCGATGGCTCATGCAATAACTTA
CAAAATCCATTGTGGGGAACTGCCAATAATCGTTATGGTCGATTGCTTACACCACGCTAT
GGCGATGGAATTCAATCACCAACAACTGCAGTCACTGGTCAAGAATTACCAAATGCTCGT
CTTGTGTCATTGATTGTTTTTGGTGAAAACGATGTTCCTGATCCACAATTTACAATTGCA
AATATGCAATGGGGACAAATTATGACACATGATATGAGTTTAACTGCAGGTGGAACACAA
TCAAGAAAACACGCAACACGTTGCTGTACAGATGATGGAAAACTTATTAGAAACAATATG
CCACAAACTTGCTATCCAATTCTTGTACCTAAAAATGATCCAGCACATTCACAAACTGGC
ACTGAATGCATGAACTTTGTAAGAACTCAAACTGATCGTGATAATAATTGTGCTGGTATT
GCAAATAATCGACCAGCTGAACAAATCACAGTTGTCACATCATACATGGATTTATCAATG
GTTTATGGCAATTCAGAGCAACAAAATCGTCCAATTCGTGCATTTACTGGTGGTAGAATG
TTGGTGGAAAATCGTGCTGGTAATGAATGGCCTCCACAAGATCCAAATGCAACTGCAAGT
TGTGATGTTCAAACACCACAAGAAACTTGCTATTTAGCTGGTGATATGAGAGTTAATCAA
AATCCAGGATTGACAATTATGCAAATTTTATTATTGAGAGAGCACAACAGAATTGCTGAC
AATTTGCAAACTATTAATCCACAATGGGATGATGAAACTGTTTTCCAAGAAGCTAGAAGA
ATTAACATTGCTCAATATCAACATATCAGTTATTATGAATGGCTTCCAATTTTCCTCGGA
CGTGAAAACATGTTGAAAAATCGTTTAATATACCAAACAACAGCTGGAAGTTTTGTCAAT
GATTACAATCCAAATATTGATCCATCAGTTTTAAATTCACATGCAACTGCTGCTTTCCGT
TATTTCCATTCACAAATTGAAGGTCGATTGGATCTTATCGCAGAATCACGATCACGTGTT
GGTTCCCTTCGTCTCAGTGATTGGTTCAATCGTCCAGTGATTGTTGAATCAGGTGACAAT
TTTGATTTCCTCAGTCGTGGCATGACAACACAACCAGAAGAACTCACTGATATTAATTTT
GATGTTGAAATTAAACACTTTTTGTTCCGTCGTGGAATGCCATTTGGTGGTGATTTGCGT
GCCATTGATATTCAAAGAAATCGTGACCATGGCTTGGCTTCTTACAATGATTTTAGAGAA
TTCTGTGGTATTCGAAGAGCAAACAGTTGGGAAGATTTTTCAGATTTAATTTCACAAAGA
GATATTGATAATTTAAGATCACTTTATGTCAGTCACGAAGATGTGGATTTGACAGTTGGT
GGATCACTTGAACAACATGTAAATGGAGCACTTGCTGGTCCAACATTCTTGTGCATTCTT
ACTGAACAATTTTATAGAACTCGTGTTGGTGATCGTTTCTTCTATGAACGTGGAGATGCC
GACATTGCATTCACTCGTGAACAATTGACAGAAATTAGAAAAGCAAGCATGGCAAGACTT
TTCTGTGATAATGGAAATAACATTGAACAAATGCAACCTGCTGCCTTTTTAAGAATTTCT
GCTGAAAATCAACTTCGACAATGCAATCAACTTCCACAAGTTGATTTATCAATGTGGCGT
GATCCATCAGCTCTTCCATCATACAGTAGTAACTTTGTAGCTGCTCAAAATGCTTTTCCT
GGATATTATCCACAATTTAATGTAAAAAAATAA
>g16975.t1 Gene=g16975 Length=690
MTLRHKISLSILTIIVDVILTSTAVHVPTSSTSYVTYHSSSSPNAYNPFVNKQITKPNSS
FYSPFFKAPAPVPSQMCPATALPPCSRSRYRTLDGSCNNLQNPLWGTANNRYGRLLTPRY
GDGIQSPTTAVTGQELPNARLVSLIVFGENDVPDPQFTIANMQWGQIMTHDMSLTAGGTQ
SRKHATRCCTDDGKLIRNNMPQTCYPILVPKNDPAHSQTGTECMNFVRTQTDRDNNCAGI
ANNRPAEQITVVTSYMDLSMVYGNSEQQNRPIRAFTGGRMLVENRAGNEWPPQDPNATAS
CDVQTPQETCYLAGDMRVNQNPGLTIMQILLLREHNRIADNLQTINPQWDDETVFQEARR
INIAQYQHISYYEWLPIFLGRENMLKNRLIYQTTAGSFVNDYNPNIDPSVLNSHATAAFR
YFHSQIEGRLDLIAESRSRVGSLRLSDWFNRPVIVESGDNFDFLSRGMTTQPEELTDINF
DVEIKHFLFRRGMPFGGDLRAIDIQRNRDHGLASYNDFREFCGIRRANSWEDFSDLISQR
DIDNLRSLYVSHEDVDLTVGGSLEQHVNGALAGPTFLCILTEQFYRTRVGDRFFYERGDA
DIAFTREQLTEIRKASMARLFCDNGNNIEQMQPAAFLRISAENQLRQCNQLPQVDLSMWR
DPSALPSYSSNFVAAQNAFPGYYPQFNVKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g16975.t1 | CDD | cd09823 | peroxinectin_like | 246 | 624 | 0.0 |
| 15 | g16975.t1 | Gene3D | G3DSA:1.10.640.10 | Myeloperoxidase | 74 | 663 | 2.3E-198 |
| 2 | g16975.t1 | PANTHER | PTHR11475 | OXIDASE/PEROXIDASE | 84 | 660 | 0.0 |
| 3 | g16975.t1 | PANTHER | PTHR11475:SF86 | PEROXIDASE | 84 | 660 | 0.0 |
| 10 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 114 | 125 | 1.2E-31 |
| 5 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 160 | 175 | 1.2E-31 |
| 8 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 311 | 329 | 1.2E-31 |
| 7 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 329 | 349 | 1.2E-31 |
| 6 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 354 | 380 | 1.2E-31 |
| 11 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 416 | 426 | 1.2E-31 |
| 9 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 538 | 558 | 1.2E-31 |
| 4 | g16975.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 612 | 626 | 1.2E-31 |
| 1 | g16975.t1 | Pfam | PF03098 | Animal haem peroxidase | 90 | 636 | 9.5E-184 |
| 16 | g16975.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 6 | - |
| 18 | g16975.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 27 | - |
| 17 | g16975.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 28 | 690 | - |
| 21 | g16975.t1 | ProSiteProfiles | PS50292 | Animal heme peroxidase superfamily profile. | 82 | 663 | 144.484 |
| 12 | g16975.t1 | SUPERFAMILY | SSF48113 | Heme-dependent peroxidases | 85 | 661 | 1.15E-178 |
| 14 | g16975.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 24 | - |
| 13 | g16975.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 27 | - |
| 20 | g16975.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006979 | response to oxidative stress | BP |
| GO:0020037 | heme binding | MF |
| GO:0004601 | peroxidase activity | MF |
| GO:0042600 | egg chorion | CC |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K19511 (peroxidase)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed