Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Serine protease inhibitor 42Dd.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2453 g2453.t148 TTS g2453.t148 18037897 18037897
chr_3 g2453 g2453.t148 isoform g2453.t148 18038066 18040145
chr_3 g2453 g2453.t148 exon g2453.t148.exon1 18038066 18038089
chr_3 g2453 g2453.t148 cds g2453.t148.CDS1 18038067 18038089
chr_3 g2453 g2453.t148 exon g2453.t148.exon2 18038878 18039019
chr_3 g2453 g2453.t148 cds g2453.t148.CDS2 18038878 18039019
chr_3 g2453 g2453.t148 exon g2453.t148.exon3 18039101 18039684
chr_3 g2453 g2453.t148 cds g2453.t148.CDS3 18039101 18039667
chr_3 g2453 g2453.t148 exon g2453.t148.exon4 18039768 18039846
chr_3 g2453 g2453.t148 exon g2453.t148.exon5 18039897 18039975
chr_3 g2453 g2453.t148 exon g2453.t148.exon6 18040042 18040145
chr_3 g2453 g2453.t148 TSS g2453.t148 18040147 18040147

Sequences

>g2453.t148 Gene=g2453 Length=1012
TTTGTGCTCTGACTATCGTGCTAAACGCATCAATGGCGTCACCCTCTGAAATCGAACAAA
AGTTTTCAAAATCAGCCAGCAACTTTGCTGCTAAATTGTACCAAAACTCAATTCAAGGAA
AAACTGGCAATGTAATTATTTCACCTGTCTCAGTTCAAACAGCCGTCACTTTGGCTATGT
TTGGGTTTCACTGATCAAATAATTGCTGATAACTATCAACGATTTGGCGAGAGCGTCGCA
AAGACTAATGGATTGAAAATCGCTAATAAGATTTATGTGATGAAAGGCTATTCAGTCAAG
CCAACATTCCAGCAAGTCGCAACAAAGAGTTTCAATTCAGAAGCTGAAGATGTAAATTTC
GCACAAAGTAAAGACTCAGCTGGCAAAATCAATACATGGGTTGAAAATCAAACAAATAAT
AAAATTAAAAATCTTATCTCACCTGATTCATTGGATGCTGACACACGTATGGTTCTTGTA
AATGCCATTTACTTCAAAGGATTCTGGACCTATCAATTTGATCCAAAAGCAACATTCAAA
GCACCATTCTTTCTCAATGATAATGATAAAGTTGATGTTGATTTCATGAAAATTAAGAAA
CATTTCAAATATGGACGATTTGATGATCTTGATGCAACTGCATTGGAATTGCCTTACAAA
GATTCTGATATTACAATGTTGATAATTTTACCAAATAAACGCACTGGATTGGCTGAATTG
GAGAGCAAATTGGACACAATTGACTTCAATGAGCTCACAACAAAGATGTATTCGGAAGAA
GTTAATGTTGAATTGCCAAAGTTTAAAATTGAATTTGACATTGAATTGACCGAGCCATTA
AAGAAGATGGGAATGGAGAAAATGTTCTCAGATGCTGCTCAATTTGATGAATTGCTTACA
TCGACTGAACCTCTCAAGGTTTCACAAGTTGTTCATAAAGCCTTCATTGAAGTCAATGAA
GAAGGTGCTGAAGCAGCTGCTGCTACAGCTATCACTATAACTCTATGCAGTT

>g2453.t148 Gene=g2453 Length=244
MKGYSVKPTFQQVATKSFNSEAEDVNFAQSKDSAGKINTWVENQTNNKIKNLISPDSLDA
DTRMVLVNAIYFKGFWTYQFDPKATFKAPFFLNDNDKVDVDFMKIKKHFKYGRFDDLDAT
ALELPYKDSDITMLIILPNKRTGLAELESKLDTIDFNELTTKMYSEEVNVELPKFKIEFD
IELTEPLKKMGMEKMFSDAAQFDELLTSTEPLKVSQVVHKAFIEVNEEGAEAAAATAITI
TLCS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g2453.t148 CDD cd19601 serpin42Da-like 1 226 0
7 g2453.t148 Gene3D G3DSA:3.30.497.10 Antithrombin 2 235 0
6 g2453.t148 Gene3D G3DSA:2.30.39.10 - 72 232 0
2 g2453.t148 PANTHER PTHR11461 SERINE PROTEASE INHIBITOR, SERPIN 4 239 0
3 g2453.t148 PANTHER PTHR11461:SF180 LEUKOCYTE ELASTASE INHIBITOR 4 239 0
1 g2453.t148 Pfam PF00079 Serpin (serine protease inhibitor) 2 240 0
5 g2453.t148 SMART SM00093 serpin2 1 243 0
4 g2453.t148 SUPERFAMILY SSF56574 Serpins 2 243 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005615 extracellular space CC
GO:0004867 serine-type endopeptidase inhibitor activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values