Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Alaserpin.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2453 g2453.t168 TTS g2453.t168 18037897 18037897
chr_3 g2453 g2453.t168 isoform g2453.t168 18038880 18039972
chr_3 g2453 g2453.t168 exon g2453.t168.exon1 18038880 18039019
chr_3 g2453 g2453.t168 cds g2453.t168.CDS1 18038882 18039019
chr_3 g2453 g2453.t168 exon g2453.t168.exon2 18039101 18039684
chr_3 g2453 g2453.t168 cds g2453.t168.CDS2 18039101 18039684
chr_3 g2453 g2453.t168 exon g2453.t168.exon3 18039768 18039972
chr_3 g2453 g2453.t168 cds g2453.t168.CDS3 18039768 18039903
chr_3 g2453 g2453.t168 TSS g2453.t168 18040147 18040147

Sequences

>g2453.t168 Gene=g2453 Length=929
TCAATTCAAGGAAAAACTGGCAATGTAATTATTTCACCTGTCTCAGTTCAAACAGCCGTC
ACTTTGGCTATGTTTGGTGCTGCTGGTGAGACCAAGCAAGAAATGTTAAAAGGTCTCGAA
TATCAGGGTTTCACTGATCAAATAATTGCTGATAACTATCAACGATTTGGCGAGAGCGTC
GCAAAGACTAATGGATTGAAAATCGCTAATAAGATTTATGTGATGAAAGGCTATTCAGTC
AAGCCAACATTCCAGCAAGTCGCAACAAAGAGTTTCAATTCAGAAGCTGAAGATGTAAAT
TTCGCACAAAGTAAAGACTCAGCTGGCAAAATCAATACATGGGTTGAAAATCAAACAAAT
AATAAAATTAAAAATCTTATCTCACCTGATTCATTGGATGCTGACACACGTATGGTTCTT
GTAAATGCCATTTACTTCAAAGGATTCTGGACCTATCAATTTGATCCAAAAGCAACATTC
AAAGCACCATTCTTTCTCAATGATAATGATAAAGTTGATGTTGATTTCATGAAAATTAAG
AAACATTTCAAATATGGACGATTTGATGATCTTGATGCAACTGCATTGGAATTGCCTTAC
AAAGATTCTGATATTACAATGTTGATAATTTTACCAAATAAACGCACTGGATTGGCTGAA
TTGGAGAGCAAATTGGACACAATTGACTTCAATGAGCTCACAACAAAGATGTATTCGGAA
GAAGTTAATGTTGAATTGCCAAAGTTTAAAATTGAATTTGACATTGAATTGACCGAGCCA
TTAAAGAAGATGGGAATGGAGAAAATGTTCTCAGATGCTGCTCAATTTGATGAATTGCTT
ACATCGACTGAACCTCTCAAGGTTTCACAAGTTGTTCATAAAGCCTTCATTGAAGTCAAT
GAAGAAGGTGCTGAAGCAGCTGCTGCTAC

>g2453.t168 Gene=g2453 Length=286
MFGAAGETKQEMLKGLEYQGFTDQIIADNYQRFGESVAKTNGLKIANKIYVMKGYSVKPT
FQQVATKSFNSEAEDVNFAQSKDSAGKINTWVENQTNNKIKNLISPDSLDADTRMVLVNA
IYFKGFWTYQFDPKATFKAPFFLNDNDKVDVDFMKIKKHFKYGRFDDLDATALELPYKDS
DITMLIILPNKRTGLAELESKLDTIDFNELTTKMYSEEVNVELPKFKIEFDIELTEPLKK
MGMEKMFSDAAQFDELLTSTEPLKVSQVVHKAFIEVNEEGAEAAAA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g2453.t168 CDD cd19601 serpin42Da-like 2 277 0
7 g2453.t168 Gene3D G3DSA:3.30.497.10 Antithrombin 2 286 0
6 g2453.t168 Gene3D G3DSA:2.30.39.10 - 123 283 0
2 g2453.t168 PANTHER PTHR11461 SERINE PROTEASE INHIBITOR, SERPIN 38 286 0
3 g2453.t168 PANTHER PTHR11461:SF180 LEUKOCYTE ELASTASE INHIBITOR 38 286 0
1 g2453.t168 Pfam PF00079 Serpin (serine protease inhibitor) 3 286 0
5 g2453.t168 SMART SM00093 serpin2 2 286 0
4 g2453.t168 SUPERFAMILY SSF56574 Serpins 2 286 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005615 extracellular space CC
GO:0004867 serine-type endopeptidase inhibitor activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed