General information for g2453.t181
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine protease inhibitor 3/4 .
Parent gene
- The parent gene g2453 is located on chr_3: 18040351..18047135 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2453 | g2453.t181 | TTS | g2453.t181 | 18038507 | 18038507 |
| chr_3 | g2453 | g2453.t181 | isoform | g2453.t181 | 18039356 | 18040145 |
| chr_3 | g2453 | g2453.t181 | exon | g2453.t181.exon1 | 18039356 | 18039684 |
| chr_3 | g2453 | g2453.t181 | cds | g2453.t181.CDS1 | 18039356 | 18039684 |
| chr_3 | g2453 | g2453.t181 | exon | g2453.t181.exon2 | 18039768 | 18039962 |
| chr_3 | g2453 | g2453.t181 | cds | g2453.t181.CDS2 | 18039768 | 18039903 |
| chr_3 | g2453 | g2453.t181 | exon | g2453.t181.exon3 | 18040042 | 18040145 |
| chr_3 | g2453 | g2453.t181 | TSS | g2453.t181 | 18040147 | 18040147 |
Sequences
>g2453.t181 Gene=g2453 Length=628
TTTGTGCTCTGACTATCGTGCTAAACGCATCAATGGCGTCACCCTCTGAAATCGAACAAA
AGTTTTCAAAATCAGCCAGCAACTTTGCTGCTAAATTGTACCAAGAAAAACTGGCAATGT
AATTATTTCACCTGTCTCAGTTCAAACAGCCGTCACTTTGGCTATGTTTGGTGCTGCTGG
TGAGACCAAGCAAGAAATGTTAAAAGGTCTCGAATATCAGGGTTTCACTGATCAAATAAT
TGCTGATAACTATCAACGATTTGGCGAGAGCGTCGCAAAGACTAATGGATTGAAAATCGC
TAATAAGATTTATGTGATGAAAGGCTATTCAGTCAAGCCAACATTCCAGCAAGTCGCAAC
AAAGAGTTTCAATTCAGAAGCTGAAGATGTAAATTTCGCACAAAGTAAAGACTCAGCTGG
CAAAATCAATACATGGGTTGAAAATCAAACAAATAATAAAATTAAAAATCTTATCTCACC
TGATTCATTGGATGCTGACACACGTATGGTTCTTGTAAATGCCATTTACTTCAAAGGATT
CTGGACCTATCAATTTGATCCAAAAGCAACATTCAAAGCACCATTCTTTCTCAATGATAA
TGATAAAGTTGATGTTGATTTCATGAAA
>g2453.t181 Gene=g2453 Length=155
MFGAAGETKQEMLKGLEYQGFTDQIIADNYQRFGESVAKTNGLKIANKIYVMKGYSVKPT
FQQVATKSFNSEAEDVNFAQSKDSAGKINTWVENQTNNKIKNLISPDSLDADTRMVLVNA
IYFKGFWTYQFDPKATFKAPFFLNDNDKVDVDFMK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g2453.t181 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 2 | 126 | 0.0000 |
| 5 | g2453.t181 | Gene3D | G3DSA:2.30.39.10 | - | 127 | 155 | 0.0000 |
| 2 | g2453.t181 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 4 | 155 | 0.0000 |
| 1 | g2453.t181 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 3 | 155 | 0.0000 |
| 4 | g2453.t181 | SMART | SM00093 | serpin2 | 2 | 155 | 0.0052 |
| 3 | g2453.t181 | SUPERFAMILY | SSF56574 | Serpins | 2 | 154 | 0.0000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
