General information for g2453.t182
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Alaserpin.
Parent gene
- The parent gene g2453 is located on chr_3: 18040351..18047135 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2453 | g2453.t182 | TTS | g2453.t182 | 18038507 | 18038507 |
| chr_3 | g2453 | g2453.t182 | isoform | g2453.t182 | 18039515 | 18040636 |
| chr_3 | g2453 | g2453.t182 | exon | g2453.t182.exon1 | 18039515 | 18039684 |
| chr_3 | g2453 | g2453.t182 | cds | g2453.t182.CDS1 | 18039515 | 18039684 |
| chr_3 | g2453 | g2453.t182 | exon | g2453.t182.exon2 | 18039768 | 18039975 |
| chr_3 | g2453 | g2453.t182 | cds | g2453.t182.CDS2 | 18039768 | 18039975 |
| chr_3 | g2453 | g2453.t182 | exon | g2453.t182.exon3 | 18040042 | 18040157 |
| chr_3 | g2453 | g2453.t182 | cds | g2453.t182.CDS3 | 18040042 | 18040157 |
| chr_3 | g2453 | g2453.t182 | exon | g2453.t182.exon4 | 18040582 | 18040636 |
| chr_3 | g2453 | g2453.t182 | cds | g2453.t182.CDS4 | 18040582 | 18040630 |
| chr_3 | g2453 | g2453.t182 | TSS | g2453.t182 | 18040724 | 18040724 |
Sequences
>g2453.t182 Gene=g2453 Length=549
ATTTTCATGCATAAAGTTCTTTCAATTCTACAATTCAGTAATCAATTTGAAACAGTAATT
CTCTCAGTTTGTGCTCTGACTATCGTGCTAAACGCATCAATGGCGTCACCCTCTGAAATC
GAACAAAAGTTTTCAAAATCAGCCAGCAACTTTGCTGCTAAATTGTACCAAAACTCAATT
CAAGGAAAAACTGGCAATGTAATTATTTCACCTGTCTCAGTTCAAACAGCCGTCACTTTG
GCTATGTTTGGTGCTGCTGGTGAGACCAAGCAAGAAATGTTAAAAGGTCTCGAATATCAG
GGTTTCACTGATCAAATAATTGCTGATAACTATCAACGATTTGGCGAGAGCGTCGCAAAG
ACTAATGGATTGAAAATCGCTAATAAGATTTATGTGATGAAAGGCTATTCAGTCAAGCCA
ACATTCCAGCAAGTCGCAACAAAGAGTTTCAATTCAGAAGCTGAAGATGTAAATTTCGCA
CAAAGTAAAGACTCAGCTGGCAAAATCAATACATGGGTTGAAAATCAAACAAATAATAAA
ATTAAAAAT
>g2453.t182 Gene=g2453 Length=181
MHKVLSILQFSNQFETVILSVCALTIVLNASMASPSEIEQKFSKSASNFAAKLYQNSIQG
KTGNVIISPVSVQTAVTLAMFGAAGETKQEMLKGLEYQGFTDQIIADNYQRFGESVAKTN
GLKIANKIYVMKGYSVKPTFQQVATKSFNSEAEDVNFAQSKDSAGKINTWVENQTNNKIK
N
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g2453.t182 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 32 | 181 | 2.0E-40 |
| 2 | g2453.t182 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 45 | 181 | 3.5E-22 |
| 1 | g2453.t182 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 45 | 181 | 1.2E-32 |
| 6 | g2453.t182 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 33 | - |
| 7 | g2453.t182 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 16 | - |
| 8 | g2453.t182 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 17 | 28 | - |
| 9 | g2453.t182 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 29 | 33 | - |
| 5 | g2453.t182 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 34 | 181 | - |
| 3 | g2453.t182 | SUPERFAMILY | SSF56574 | Serpins | 30 | 181 | 3.14E-34 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
