General information for g7689.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Adenosine deaminase 2.
Parent gene
- The parent gene g7689 is located on chr_2: 25255156..25256640 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7689 | g7689.t1 | isoform | g7689.t1 | 25255156 | 25256640 |
| chr_2 | g7689 | g7689.t1 | exon | g7689.t1.exon1 | 25255156 | 25255525 |
| chr_2 | g7689 | g7689.t1 | cds | g7689.t1.CDS1 | 25255156 | 25255525 |
| chr_2 | g7689 | g7689.t1 | exon | g7689.t1.exon2 | 25255584 | 25255616 |
| chr_2 | g7689 | g7689.t1 | cds | g7689.t1.CDS2 | 25255584 | 25255616 |
| chr_2 | g7689 | g7689.t1 | exon | g7689.t1.exon3 | 25255674 | 25256068 |
| chr_2 | g7689 | g7689.t1 | cds | g7689.t1.CDS3 | 25255674 | 25256068 |
| chr_2 | g7689 | g7689.t1 | exon | g7689.t1.exon4 | 25256125 | 25256362 |
| chr_2 | g7689 | g7689.t1 | cds | g7689.t1.CDS4 | 25256125 | 25256362 |
| chr_2 | g7689 | g7689.t1 | exon | g7689.t1.exon5 | 25256429 | 25256640 |
| chr_2 | g7689 | g7689.t1 | cds | g7689.t1.CDS5 | 25256429 | 25256640 |
| chr_2 | g7689 | g7689.t1 | TSS | g7689.t1 | NA | NA |
| chr_2 | g7689 | g7689.t1 | TTS | g7689.t1 | NA | NA |
Sequences
>g7689.t1 Gene=g7689 Length=1248
ATGTCACATTTTGAGCGACAAATTTTTAGTTTATTACTGCTTTTTGCAACGTTCACAAGC
CTTGCAGTCGCGCGAGTTACAGCAGCAATGGGAAGCATAAATGTAGAGTCAGAACGTCCA
TCATTTGAAAAGTATACAAAATTACGTCAAGAATATGTAAATGAACATCAAGCAAGAGCT
TTAGGCTCAGATGTGTTACTTTCTGAAGATGAAAAACATTTTAATAGCGTATTGATGGAC
TTAAAGGCTGATGAATTGGCACGTGGTTTTGACAATCCTTTCAATTTCACTCCCGCACGA
CATTTTTTTACTGCCATGAAATCTATTGAGACTTCACCACTTTTTAAACTCATTCAGAAA
ATGCCAAAAGGAGCCATTCTGCATGCTCATGACGACGCAATCTGTTCAACTGACTATGTC
GTATCGTTAACAAAATGGGAGAATCTTTGGCAATGGGGTAATCTTGAGGGTGATGATTTG
CCAAAATTTCTGTTTAGTCGGCAAAAGCCAGAGAAAATAGACAATGTTGAATGGAGACTT
GTAAGCGACATAAGGAAGGAAATGGGTGACGATTTGTATGAAAGCAAAGTCAGACGCTTT
TTTACTCTGATTGTTGACGATCCGACCAGGCAGTATGCTGATATTAATCAAGCATGGAAC
AAATTTATGGACATGTTTGGTGTTGTAGGGCCAATTGTTACTTATACTGAAGCATGGCGT
GATTATTACAGACAAACACTTCAAGAGCTCTATGATGATAATGTGCAATATTTAGAATTT
AGAGGTTTACTGCCAGAGCTTTATGATCTTGATGGAAAAAAATATGGACCAATTGAATGT
GCTCAAATTTATGTTGATGTATTAAAAGATTTTAAACAATCGCATCCAGATTTTGTTGGA
TCAAAATTTATTTTTGCTCCACTTCGTGGTGTTGATGATGAAATATTCGACAGCTACTTA
CCAATTTTACAAAAGCTTATGAATAGATTCCCTGAATTCATTGCCGGATTTGATTTAGTT
GGACAAGAAGATAAAGGACGACCACTTATAGAATATGCAGAGAGATTCCTCAAGTATCCA
AGTGACATTAAATTTTTCTTTCATGCAGGCGAGACTAATTGGATGGGAACAACTTCAGAT
GAAAATTTGGTAAAAAAAAATTCTTTTTGCATTTTCTACAAAATTAGAGCAATTCTTAAT
ACATTTAGTTCAATCCTATTGAGTTGCATTTTAATTGAATATTGCTAA
>g7689.t1 Gene=g7689 Length=415
MSHFERQIFSLLLLFATFTSLAVARVTAAMGSINVESERPSFEKYTKLRQEYVNEHQARA
LGSDVLLSEDEKHFNSVLMDLKADELARGFDNPFNFTPARHFFTAMKSIETSPLFKLIQK
MPKGAILHAHDDAICSTDYVVSLTKWENLWQWGNLEGDDLPKFLFSRQKPEKIDNVEWRL
VSDIRKEMGDDLYESKVRRFFTLIVDDPTRQYADINQAWNKFMDMFGVVGPIVTYTEAWR
DYYRQTLQELYDDNVQYLEFRGLLPELYDLDGKKYGPIECAQIYVDVLKDFKQSHPDFVG
SKFIFAPLRGVDDEIFDSYLPILQKLMNRFPEFIAGFDLVGQEDKGRPLIEYAERFLKYP
SDIKFFFHAGETNWMGTTSDENLVKKNSFCIFYKIRAILNTFSSILLSCILIEYC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7689.t1 | Gene3D | G3DSA:3.20.20.140 | - | 43 | 387 | 9.2E-96 |
| 2 | g7689.t1 | PANTHER | PTHR11409 | ADENOSINE DEAMINASE | 77 | 384 | 6.2E-79 |
| 3 | g7689.t1 | PANTHER | PTHR11409:SF39 | ADENOSINE DEAMINASE 2 | 77 | 384 | 6.2E-79 |
| 1 | g7689.t1 | Pfam | PF08451 | Adenosine/AMP deaminase N-terminal | 33 | 118 | 7.8E-21 |
| 9 | g7689.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 24 | - |
| 10 | g7689.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 7 | - |
| 11 | g7689.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 8 | 19 | - |
| 12 | g7689.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 20 | 24 | - |
| 8 | g7689.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 25 | 415 | - |
| 4 | g7689.t1 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases | 91 | 383 | 2.89E-39 |
| 6 | g7689.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 24 | - |
| 5 | g7689.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 31 | - |
| 14 | g7689.t1 | TIGRFAM | TIGR01431 | adm_rel: adenosine deaminase-related growth factor | 45 | 384 | 9.9E-101 |
| 13 | g7689.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
| GO:0004000 | adenosine deaminase activity | MF |
| GO:0006154 | adenosine catabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
